PRUCCOLI, LETIZIA
PRUCCOLI, LETIZIA
DIPARTIMENTO DI SCIENZE PER LA QUALITA' DELLA VITA
Assegnisti
Chalcone-based carbamates for Alzheimer's disease treatment
2017 Rampa, Angela; Montanari, Serena; Pruccoli, Letizia; Bartolini, Manuela; Falchi, Federico; Feoli, Alessandra; Cavalli, Andrea; Belluti, Federica; Gobbi, Silvia; Tarozzi, Andrea; Bisi, Alessandra
Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases
2020 Cindy Juliet Cristancho Ortiz; Caio Miranda Damasio; Letizia Pruccoli; Nathália Fonseca Nadur; Luciana Luiza de Azevedo; Isabella Alvim Guedes; Laurent Emmanuel Dardenne; Arthur Eugen Kümmerle; Andrea Tarozzi; Claudio Viegas Jr
Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate.
2016 Tarozzi, A; Marchetti, C; Nicolini, B; D'Amico, M; Ticchi, N; Pruccoli, L; Tumiatti, V; Simoni, E; Lodola, A; Mor, M; Milelli, A; Minarini, A.
Comparison of Adaptive Neuroprotective Mechanisms of Sulforaphane and its Interconversion Product Erucin in in Vitro and in Vivo Models of Parkinson's Disease
2018 Morroni Fabiana, Sita Giulia, Djemil Alice, D'Amico Massimo, Pruccoli Letizia, Cantelli-Forti Giorgio, Hrelia Patrizia, Tarozzi Andrea.
Curcumin and Heme Oxygenase: Neuroprotection and Beyond
2019 Emanuela Mhillaj, Andrea Tarozzi, Letizia Pruccoli, Vincenzo Cuomo, Luigia Trabace, Cesare Mancuso
Design and synthesis of H 2 S-donor hybrids: A new treatment for Alzheimer's disease?
2019 Simona Sestito, Letizia Pruccoli, Massimiliano Runfola, Valentina Citi, Alma Martelli, Giuseppe Saccomanni, Vincenzo Calderone, Andrea Tarozzi, Simona Rapposell
Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease
2020 Matheus de Freitas Silva; Ellen Tardelli Lima; Letizia Pruccoli; Newton G Castro; Marcos Jorge R Guimarães; Fernanda M R da Silva; Nathalia Fonseca Nadur; Luciana Luiz de Azevedo; Arthur Eugen Kümmerle; Isabella Alvim Guedes; Laurent Emmanuel Dardenne; Vanessa Silva Gontijo; Andrea Tarozzi; Claudio Viegas
Design, synthesis and evaluation of novel feruloyl-donepezil hybrids as potential multitarget drugs for the treatment of Alzheimer's disease
2017 Dias, Kris Simone T.; de Paula, Cynthia T.; dos Santos, Thiago; Souza, Isis N.O.; Boni, Marina S.; Guimarães, Marcos J.R.; da Silva, Fernanda M.R.; Castro, Newton G.; Neves, Gilda A.; Veloso, Clarice C.; Coelho, Márcio M.; de Melo, Ivo Souza F.; Giusti, Fabiana C.V.; Giusti-Paiva, Alexandre; da Silva, Marcelo L.; Dardenne, Laurent E.; Guedes, Isabella A.; Pruccoli, Letizia; Morroni, Fabiana; Tarozzi, Andrea; Viegas, Claudio*
Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates
2018 Dias Viegas, Flávia Pereira; de Freitas Silva, Matheus; Divino da Rocha, Miguel; Castelli, Maísa Rosa; Riquiel, Mariana Máximo; Machado, Rafael Pereira; Vaz, Sarah Macedo; Simões de Lima, Laís Medeiros; Mancini, Karla Cristine; Marques de Oliveira, Patrícia Cruz; Morais, Élida Parreira; Gontijo, Vanessa Silva; da Silva, Fernanda Motta R.; D'Alincourt da Fonseca Peçanha, Dora; Castro, Newton Gonçalves; Neves, Gilda A.; Giusti-Paiva, Alexandre; Vilela, Fabiana Cardoso; Orlandi, Lidiane; Camps, Ihosvany; Veloso, Márcia Paranho; Leomil Coelho, Luis Felipe; Ionta, Marisa; Ferreira-Silva, Guilherme Álvaro; Pereira, Rodrigo Machado; Dardenne, Laurent E.; Guedes, Isabella Alvim; de Oliveira Carneiro Junior, Wellerson; Quaglio Bellozi, Paula Maria; Pinheiro de Oliveira, Antônio Carlos; Ferreira, Fábio Furlan; Pruccoli, Letizia; Tarozzi, Andrea; Viegas, Claudio*
Design, synthesis, and biological evaluation of new thalidomide–donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation
2022 Cindy Juliet Cristancho Ortiz, Matheus de Freitas Silva, Letizia Pruccoli, Nathália Fonseca Nadur, Luciana Luíza de Azevedo, Arthur Eugen Kümmerle, Isabella Alvim Guedes, Laurent Emmanuel Dardenne, Luiz Felipe Leomil Coelho, Marcos J. Guimarães, Fernanda M. R. da Silva, Newton Castro, Vanessa Silva Gontijo, Viviana C. T. Rojas, Merelym Ketterym de Oliveira, Fabiana Cardoso Vilela, Alexandre Giusti-Paiva, Gisele Barbosa, Lídia Moreira Lima, Gabriela Beserra Pinheiro, Letícia Germino Veras, Márcia Renata Mortari, Andrea Tarozzi, Claudio Viegas Jr
Development of new extracts of crocus sativus l. By-product from two different italian regions as new potential active ingredient in cosmetic formulations
2021 Gigliobianco M.R.; Cortese M.; Peregrina D.V.; Villa C.; Lupidi G.; Pruccoli L.; Angeloni C.; Tarozzi A.; Censi R.; Di Martino P.
Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment
2019 Montanari S.; Mahmoud A.M.; Pruccoli L.; Rabbito A.; Naldi M.; Petralla S.; Moraleda I.; Bartolini M.; Monti B.; Iriepa I.; Belluti F.; Gobbi S.; Di Marzo V.; Bisi A.; Tarozzi A.; Ligresti A.; Rampa A.
Dysregulation of long non-coding RNAs in neuroinflammation: characterization of LINC00520 and its possible role in Parkinson's disease
2021 Martina Fazzina, Letizia Pruccoli, Andrea Tarozzi, Francesca Massenzio, Barbara Monti, Davide Maestri, Matteo Bergonzoni, Flavia Frabetti, Raffaella Casadei
Esculetin as a Bifunctional Antioxidant Prevents and Counteracts the Oxidative Stress and Neuronal Death Induced by Amyloid Protein in SH-SY5Y Cells
2020 Pruccoli, L; Morroni, F; Sita, G; Hrelia, P; Tarozzi, A
Esculetin provides neuroprotection against mutant huntingtin-induced toxicity in huntington’s disease models
2021 Pruccoli L.; Breda C.; Teti G.; Falconi M.; Giorgini F.; Tarozzi A.
Exploiting the chalcone scaffold to develop multifunctional agents for Alzheimer’s disease
2018 Rampa, Angela*; Bartolini, Manuela; Pruccoli, Letizia; Naldi, Marina; Iriepa, Isabel; Moraleda, Ignacio; Belluti, Federica; Gobbi, Silvia; Tarozzi, Andrea; Bisi, Alessandra
Heat stress as a potential risk factor for vitamin D deficiency
2023 Balducci M.; Pruccoli L.; Tarozzi A.
Influence of Guanine-Based Purines on the Oxidoreductive Reactions Involved in Normal or Altered Brain Functions
2023 Zuccarini M.; Pruccoli L.; Balducci M.; Giuliani P.; Caciagli F.; Ciccarelli R.; Di Iorio P.
Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives
2016 Montanari, Serena; Bartolini, Manuela; Neviani, Paolo; Belluti, Federica; Gobbi, Silvia; Pruccoli, Letizia; Tarozzi, Andrea; Falchi, Federico; Andrisano, Vincenza; Miszta, Przemysław; Cavalli, Andrea; Filipek, Sławomir; Bisi, Alessandra; Rampa, Angela
Naturally inspired molecules as multifunctional agents for Alzheimer's disease treatment
2016 Rampa, Angela; Tarozzi, Andrea; Mancini, Francesca; Pruccoli, Letizia; Di Martino, Rita Maria Concetta; Gobbi, Silvia; Bisi, Alessandra; De Simone, Angela; Palomba, Francesco; Zaccheroni, Nelsi; Belluti, Federica
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Chalcone-based carbamates for Alzheimer's disease treatment | Rampa, Angela; Montanari, Serena; Pruccoli, Letizia; Bartolini, Manuela; Falchi, Federico; Feoli,... Alessandra; Cavalli, Andrea; Belluti, Federica; Gobbi, Silvia; Tarozzi, Andrea; Bisi, Alessandra | 2017-01-01 | FUTURE MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases | Cindy Juliet Cristancho Ortiz; Caio Miranda Damasio; Letizia Pruccoli; Nathália Fonseca Nadur; Lu...ciana Luiza de Azevedo; Isabella Alvim Guedes; Laurent Emmanuel Dardenne; Arthur Eugen Kümmerle; Andrea Tarozzi; Claudio Viegas Jr | 2020-01-01 | NEUROCHEMICAL RESEARCH | - | 1.01 Articolo in rivista | - |
| Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate. | Tarozzi, A; Marchetti, C; Nicolini, B; D'Amico, M; Ticchi, N; Pruccoli, L; Tumiatti, V; Simoni, E...; Lodola, A; Mor, M; Milelli, A; Minarini, A. | 2016-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Comparison of Adaptive Neuroprotective Mechanisms of Sulforaphane and its Interconversion Product Erucin in in Vitro and in Vivo Models of Parkinson's Disease | Morroni Fabiana, Sita Giulia, Djemil Alice, D'Amico Massimo, Pruccoli Letizia, Cantelli-Fort...i Giorgio, Hrelia Patrizia, Tarozzi Andrea. | 2018-01-01 | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | - | 1.01 Articolo in rivista | acs.jafc.7b04641.pdf |
| Curcumin and Heme Oxygenase: Neuroprotection and Beyond | Emanuela Mhillaj, Andrea Tarozzi, Letizia Pruccoli, Vincenzo Cuomo, Luigia Trabace, Cesare Mancuso | 2019-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-Tarozzi 2019.pdf |
| Design and synthesis of H 2 S-donor hybrids: A new treatment for Alzheimer's disease? | Simona Sestito, Letizia Pruccoli, Massimiliano Runfola, Valentina Citi, Alma Martelli, Giuseppe S...accomanni, Vincenzo Calderone, Andrea Tarozzi, Simona Rapposell | 2019-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease | Matheus de Freitas Silva; Ellen Tardelli Lima; Letizia Pruccoli; Newton G Castro; Marcos Jorge R ...Guimarães; Fernanda M R da Silva; Nathalia Fonseca Nadur; Luciana Luiz de Azevedo; Arthur Eugen Kümmerle; Isabella Alvim Guedes; Laurent Emmanuel Dardenne; Vanessa Silva Gontijo; Andrea Tarozzi; Claudio Viegas | 2020-01-01 | MOLECULES | - | 1.01 Articolo in rivista | molecules-25-03165.pdf |
| Design, synthesis and evaluation of novel feruloyl-donepezil hybrids as potential multitarget drugs for the treatment of Alzheimer's disease | Dias, Kris Simone T.; de Paula, Cynthia T.; dos Santos, Thiago; Souza, Isis N.O.; Boni, Marina S....; Guimarães, Marcos J.R.; da Silva, Fernanda M.R.; Castro, Newton G.; Neves, Gilda A.; Veloso, Clarice C.; Coelho, Márcio M.; de Melo, Ivo Souza F.; Giusti, Fabiana C.V.; Giusti-Paiva, Alexandre; da Silva, Marcelo L.; Dardenne, Laurent E.; Guedes, Isabella A.; Pruccoli, Letizia; Morroni, Fabiana; Tarozzi, Andrea; Viegas, Claudio* | 2017-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | acceptedEJMECH-D-16-01536R2.pdf |
| Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates | Dias Viegas, Flávia Pereira; de Freitas Silva, Matheus; Divino da Rocha, Miguel; Castelli, Maísa ...Rosa; Riquiel, Mariana Máximo; Machado, Rafael Pereira; Vaz, Sarah Macedo; Simões de Lima, Laís Medeiros; Mancini, Karla Cristine; Marques de Oliveira, Patrícia Cruz; Morais, Élida Parreira; Gontijo, Vanessa Silva; da Silva, Fernanda Motta R.; D'Alincourt da Fonseca Peçanha, Dora; Castro, Newton Gonçalves; Neves, Gilda A.; Giusti-Paiva, Alexandre; Vilela, Fabiana Cardoso; Orlandi, Lidiane; Camps, Ihosvany; Veloso, Márcia Paranho; Leomil Coelho, Luis Felipe; Ionta, Marisa; Ferreira-Silva, Guilherme Álvaro; Pereira, Rodrigo Machado; Dardenne, Laurent E.; Guedes, Isabella Alvim; de Oliveira Carneiro Junior, Wellerson; Quaglio Bellozi, Paula Maria; Pinheiro de Oliveira, Antônio Carlos; Ferreira, Fábio Furlan; Pruccoli, Letizia; Tarozzi, Andrea; Viegas, Claudio* | 2018-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | j.ejmech.2018.01.066.pdf |
| Design, synthesis, and biological evaluation of new thalidomide–donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation | Cindy Juliet Cristancho Ortiz, Matheus de Freitas Silva, Letizia Pruccoli, Nathália Fonseca Nadur..., Luciana Luíza de Azevedo, Arthur Eugen Kümmerle, Isabella Alvim Guedes, Laurent Emmanuel Dardenne, Luiz Felipe Leomil Coelho, Marcos J. Guimarães, Fernanda M. R. da Silva, Newton Castro, Vanessa Silva Gontijo, Viviana C. T. Rojas, Merelym Ketterym de Oliveira, Fabiana Cardoso Vilela, Alexandre Giusti-Paiva, Gisele Barbosa, Lídia Moreira Lima, Gabriela Beserra Pinheiro, Letícia Germino Veras, Márcia Renata Mortari, Andrea Tarozzi, Claudio Viegas Jr | 2022-01-01 | RSC MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Manuscript RSC TAROZZI Andrea.pdf |
| Development of new extracts of crocus sativus l. By-product from two different italian regions as new potential active ingredient in cosmetic formulations | Gigliobianco M.R.; Cortese M.; Peregrina D.V.; Villa C.; Lupidi G.; Pruccoli L.; Angeloni C.; Tar...ozzi A.; Censi R.; Di Martino P. | 2021-01-01 | COSMETICS | - | 1.01 Articolo in rivista | Cosmetics 8-2-2021.pdf |
| Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment | Montanari S.; Mahmoud A.M.; Pruccoli L.; Rabbito A.; Naldi M.; Petralla S.; Moraleda I.; Bartolin...i M.; Monti B.; Iriepa I.; Belluti F.; Gobbi S.; Di Marzo V.; Bisi A.; Tarozzi A.; Ligresti A.; Rampa A. | 2019-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | benzo AM .pdf |
| Dysregulation of long non-coding RNAs in neuroinflammation: characterization of LINC00520 and its possible role in Parkinson's disease | Martina Fazzina, Letizia Pruccoli, Andrea Tarozzi, Francesca Massenzio, Barbara Monti, Davide Mae...stri, Matteo Bergonzoni, Flavia Frabetti, Raffaella Casadei | 2021-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Esculetin as a Bifunctional Antioxidant Prevents and Counteracts the Oxidative Stress and Neuronal Death Induced by Amyloid Protein in SH-SY5Y Cells | Pruccoli, L; Morroni, F; Sita, G; Hrelia, P; Tarozzi, A | 2020-01-01 | ANTIOXIDANTS | - | 1.01 Articolo in rivista | antioxidants-09-00551.pdf |
| Esculetin provides neuroprotection against mutant huntingtin-induced toxicity in huntington’s disease models | Pruccoli L.; Breda C.; Teti G.; Falconi M.; Giorgini F.; Tarozzi A. | 2021-01-01 | PHARMACEUTICALS | - | 1.01 Articolo in rivista | Pharmaceuticals 14 2021.pdf; pharmaceuticals-14-01044-s001.zip |
| Exploiting the chalcone scaffold to develop multifunctional agents for Alzheimer’s disease | Rampa, Angela*; Bartolini, Manuela; Pruccoli, Letizia; Naldi, Marina; Iriepa, Isabel; Moraleda, I...gnacio; Belluti, Federica; Gobbi, Silvia; Tarozzi, Andrea; Bisi, Alessandra | 2018-01-01 | MOLECULES | - | 1.01 Articolo in rivista | molecules-23-01902-v3.pdf |
| Heat stress as a potential risk factor for vitamin D deficiency | Balducci M.; Pruccoli L.; Tarozzi A. | 2023-01-01 | MEDICAL HYPOTHESES | - | 1.01 Articolo in rivista | Revised manuscript.pdf |
| Influence of Guanine-Based Purines on the Oxidoreductive Reactions Involved in Normal or Altered Brain Functions | Zuccarini M.; Pruccoli L.; Balducci M.; Giuliani P.; Caciagli F.; Ciccarelli R.; Di Iorio P. | 2023-01-01 | JOURNAL OF CLINICAL MEDICINE | - | 1.01 Articolo in rivista | jcm-12-01172-v2.pdf |
| Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives | Montanari, Serena; Bartolini, Manuela; Neviani, Paolo; Belluti, Federica; Gobbi, Silvia; Pruccoli..., Letizia; Tarozzi, Andrea; Falchi, Federico; Andrisano, Vincenza; Miszta, Przemysław; Cavalli, Andrea; Filipek, Sławomir; Bisi, Alessandra; Rampa, Angela | 2016-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | ChemMedChem VQR.pdf |
| Naturally inspired molecules as multifunctional agents for Alzheimer's disease treatment | Rampa, Angela; Tarozzi, Andrea; Mancini, Francesca; Pruccoli, Letizia; Di Martino, Rita Maria Con...cetta; Gobbi, Silvia; Bisi, Alessandra; De Simone, Angela; Palomba, Francesco; Zaccheroni, Nelsi; Belluti, Federica | 2016-01-01 | MOLECULES | - | 1.01 Articolo in rivista | molecules-21-00643.pdf |