PRUCCOLI, LETIZIA
PRUCCOLI, LETIZIA
DIPARTIMENTO DI SCIENZE PER LA QUALITA' DELLA VITA
Assegnisti
Synthesis and pharmacological evaluation of novel N-aryl-cinnamoyl-hydrazone hybrids designed as neuroprotective agents for the treatment of Parkinson’s disease
2024 Matheus de Freitas Silva, Cindy Juliet Cristancho Ortiz, Letícia Ferreira Coelho, Letizia Pruccoli, Barbara Pagliarani, Leonardo Pisani, Marco Catto, Giulio Poli, Tiziano Tuccinardi, Fabiana Cardoso Vilela, Alexandre Giusti-Paiva, Marina Amaral Alves, Hygor M. Ribeiro de Souza, Andrea Tarozzi, Vanessa Silva Gontijo, Claudio Viegas Jr.
Heat stress as a potential risk factor for vitamin D deficiency
2023 Balducci M.; Pruccoli L.; Tarozzi A.
Influence of Guanine-Based Purines on the Oxidoreductive Reactions Involved in Normal or Altered Brain Functions
2023 Zuccarini M.; Pruccoli L.; Balducci M.; Giuliani P.; Caciagli F.; Ciccarelli R.; Di Iorio P.
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease
2023 Guardigni M.; Pruccoli L.; Santini A.; Simone A.D.; Bersani M.; Spyrakis F.; Frabetti F.; Uliassi E.; Andrisano V.; Pagliarani B.; Fernández-Gómez P.; Palomo V.; Bolognesi M.L.; Tarozzi A.; Milelli A.
Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold
2023 De Lorenzi, Ersilia; Seghetti, Francesca; Tarozzi, Andrea; Pruccoli, Letizia; Contardi, Cecilia; Serra, Massimo; Bisi, Alessandra; Gobbi, Silvia; Vistoli, Giulio; Gervasoni, Silvia; Argentini, Carla; Ghirardo, Giulia; Guarato, Giulia; Orso, Genny; Belluti, Federica; Di Martino, Rita Maria Concetta; Zusso, Morena
Design, synthesis, and biological evaluation of new thalidomide–donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation
2022 Cindy Juliet Cristancho Ortiz, Matheus de Freitas Silva, Letizia Pruccoli, Nathália Fonseca Nadur, Luciana Luíza de Azevedo, Arthur Eugen Kümmerle, Isabella Alvim Guedes, Laurent Emmanuel Dardenne, Luiz Felipe Leomil Coelho, Marcos J. Guimarães, Fernanda M. R. da Silva, Newton Castro, Vanessa Silva Gontijo, Viviana C. T. Rojas, Merelym Ketterym de Oliveira, Fabiana Cardoso Vilela, Alexandre Giusti-Paiva, Gisele Barbosa, Lídia Moreira Lima, Gabriela Beserra Pinheiro, Letícia Germino Veras, Márcia Renata Mortari, Andrea Tarozzi, Claudio Viegas Jr
PROTAC-INDUCED GLYCOGEN SYNTHASE KINASE 3B DEGRADATION
2022 Santini, A.; Pruccoli, L.; Guardigni, M.; De Simone, A.; Spyrakis, F.; Frabetti, F.; Andrisano, V.; Bolognesi, M. L.; Tarozzi, A.; Milelli, A.
Protective effects of chrysin against the neurotoxicity induced by aluminium: In vitro and in vivo studies
2022 Campos H.M.; da Costa M.; da Silva Moreira L.K.; da Silva Neri H.F.; Branco da Silva C.R.; Pruccoli L.; dos Santos F.C.A.; Costa E.A.; Tarozzi A.; Ghedini P.C.
Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer’s disease
2022 Sarah Macedo Vaz, Matheus de Freitas Silva, Graziella dos Reis Rosa Franco, Marcos Jorge R. Guimaraes, Fernanda Motta R. da Silva, Newton Gonçalves Castro, Isabella Alvim Guedes, Laurent E. Dardenne, Marina Amaral Alves, Rafael Garrett da Costa, Gabriela Beserra Pinheiro, Letícia Germino Veras, Marcia Renata Mortari, Letizia Pruccoli, Andrea Tarozzi, Claudio ´ Viegas Jr.
Development of new extracts of crocus sativus l. By-product from two different italian regions as new potential active ingredient in cosmetic formulations
2021 Gigliobianco M.R.; Cortese M.; Peregrina D.V.; Villa C.; Lupidi G.; Pruccoli L.; Angeloni C.; Tarozzi A.; Censi R.; Di Martino P.
Dysregulation of long non-coding RNAs in neuroinflammation: characterization of LINC00520 and its possible role in Parkinson's disease
2021 Martina Fazzina, Letizia Pruccoli, Andrea Tarozzi, Francesca Massenzio, Barbara Monti, Davide Maestri, Matteo Bergonzoni, Flavia Frabetti, Raffaella Casadei
Esculetin provides neuroprotection against mutant huntingtin-induced toxicity in huntington’s disease models
2021 Pruccoli L.; Breda C.; Teti G.; Falconi M.; Giorgini F.; Tarozzi A.
New antioxidant ingredients from brewery by-products for cosmetic formulations
2021 Censi R.; Peregrina D.V.; Gigliobianco M.R.; Lupidi G.; Angeloni C.; Pruccoli L.; Tarozzi A.; Di Martino P.
Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases
2020 Cindy Juliet Cristancho Ortiz; Caio Miranda Damasio; Letizia Pruccoli; Nathália Fonseca Nadur; Luciana Luiza de Azevedo; Isabella Alvim Guedes; Laurent Emmanuel Dardenne; Arthur Eugen Kümmerle; Andrea Tarozzi; Claudio Viegas Jr
Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease
2020 Matheus de Freitas Silva; Ellen Tardelli Lima; Letizia Pruccoli; Newton G Castro; Marcos Jorge R Guimarães; Fernanda M R da Silva; Nathalia Fonseca Nadur; Luciana Luiz de Azevedo; Arthur Eugen Kümmerle; Isabella Alvim Guedes; Laurent Emmanuel Dardenne; Vanessa Silva Gontijo; Andrea Tarozzi; Claudio Viegas
Esculetin as a Bifunctional Antioxidant Prevents and Counteracts the Oxidative Stress and Neuronal Death Induced by Amyloid Protein in SH-SY5Y Cells
2020 Pruccoli, L; Morroni, F; Sita, G; Hrelia, P; Tarozzi, A
Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease
2020 Rita Maria Concetta Di Martino; Letizia Pruccoli; Alessandra Bisi; Silvia Gobbi; Angela Rampa; Ana Martinez; Concepción Pérez; Loreto Martinez-Gonzalez; Maria Paglione; Elia Di Schiavi; Francesca Seghetti; Andrea Tarozzi; Federica Belluti
Optimization of the Extraction from Spent Coffee Grounds Using the Desirability Approach
2020 Maria Rosa Gigliobianco; Barbara Campisi; Dolores Vargas Peregrina; Roberta Censi; Gulzhan Khamitova; Simone Angeloni; Giovanni Caprioli; Marco Zannotti; Stefano Ferraro; Rita Giovannetti; Cristina Angeloni; Giulio Lupidi; Letizia Pruccoli; Andrea Tarozzi; Dario Voinovich; Piera Di Martino
Curcumin and Heme Oxygenase: Neuroprotection and Beyond
2019 Emanuela Mhillaj, Andrea Tarozzi, Letizia Pruccoli, Vincenzo Cuomo, Luigia Trabace, Cesare Mancuso
Design and synthesis of H 2 S-donor hybrids: A new treatment for Alzheimer's disease?
2019 Simona Sestito, Letizia Pruccoli, Massimiliano Runfola, Valentina Citi, Alma Martelli, Giuseppe Saccomanni, Vincenzo Calderone, Andrea Tarozzi, Simona Rapposell
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Synthesis and pharmacological evaluation of novel N-aryl-cinnamoyl-hydrazone hybrids designed as neuroprotective agents for the treatment of Parkinson’s disease | Matheus de Freitas Silva, Cindy Juliet Cristancho Ortiz, Letícia Ferreira Coelho, Letizia Pruccol...i, Barbara Pagliarani, Leonardo Pisani, Marco Catto, Giulio Poli, Tiziano Tuccinardi, Fabiana Cardoso Vilela, Alexandre Giusti-Paiva, Marina Amaral Alves, Hygor M. Ribeiro de Souza, Andrea Tarozzi, Vanessa Silva Gontijo, Claudio Viegas Jr. | 2024-01-01 | BIOORGANIC CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Heat stress as a potential risk factor for vitamin D deficiency | Balducci M.; Pruccoli L.; Tarozzi A. | 2023-01-01 | MEDICAL HYPOTHESES | - | 1.01 Articolo in rivista | Revised manuscript.pdf |
| Influence of Guanine-Based Purines on the Oxidoreductive Reactions Involved in Normal or Altered Brain Functions | Zuccarini M.; Pruccoli L.; Balducci M.; Giuliani P.; Caciagli F.; Ciccarelli R.; Di Iorio P. | 2023-01-01 | JOURNAL OF CLINICAL MEDICINE | - | 1.01 Articolo in rivista | jcm-12-01172-v2.pdf |
| PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease | Guardigni M.; Pruccoli L.; Santini A.; Simone A.D.; Bersani M.; Spyrakis F.; Frabetti F.; Uliassi... E.; Andrisano V.; Pagliarani B.; Fernández-Gómez P.; Palomo V.; Bolognesi M.L.; Tarozzi A.; Milelli A. | 2023-01-01 | ACS CHEMICAL NEUROSCIENCE | - | 1.01 Articolo in rivista | acschemneuro.3c00096.pdf; cn3c00096_si_001.pdf |
| Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold | De Lorenzi, Ersilia; Seghetti, Francesca; Tarozzi, Andrea; Pruccoli, Letizia; Contardi, Cecilia; ...Serra, Massimo; Bisi, Alessandra; Gobbi, Silvia; Vistoli, Giulio; Gervasoni, Silvia; Argentini, Carla; Ghirardo, Giulia; Guarato, Giulia; Orso, Genny; Belluti, Federica; Di Martino, Rita Maria Concetta; Zusso, Morena | 2023-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold.pdf; 1-s2.0-S0223523423002635-mmc1.pdf |
| Design, synthesis, and biological evaluation of new thalidomide–donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation | Cindy Juliet Cristancho Ortiz, Matheus de Freitas Silva, Letizia Pruccoli, Nathália Fonseca Nadur..., Luciana Luíza de Azevedo, Arthur Eugen Kümmerle, Isabella Alvim Guedes, Laurent Emmanuel Dardenne, Luiz Felipe Leomil Coelho, Marcos J. Guimarães, Fernanda M. R. da Silva, Newton Castro, Vanessa Silva Gontijo, Viviana C. T. Rojas, Merelym Ketterym de Oliveira, Fabiana Cardoso Vilela, Alexandre Giusti-Paiva, Gisele Barbosa, Lídia Moreira Lima, Gabriela Beserra Pinheiro, Letícia Germino Veras, Márcia Renata Mortari, Andrea Tarozzi, Claudio Viegas Jr | 2022-01-01 | RSC MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Manuscript RSC TAROZZI Andrea.pdf |
| PROTAC-INDUCED GLYCOGEN SYNTHASE KINASE 3B DEGRADATION | Santini, A.; Pruccoli, L.; Guardigni, M.; De Simone, A.; Spyrakis, F.; Frabetti, F.; Andrisano, V....; Bolognesi, M. L.; Tarozzi, A.; Milelli, A. | 2022-01-01 | - | - | 4.03 Poster | - |
| Protective effects of chrysin against the neurotoxicity induced by aluminium: In vitro and in vivo studies | Campos H.M.; da Costa M.; da Silva Moreira L.K.; da Silva Neri H.F.; Branco da Silva C.R.; Prucco...li L.; dos Santos F.C.A.; Costa E.A.; Tarozzi A.; Ghedini P.C. | 2022-01-01 | TOXICOLOGY | - | 1.01 Articolo in rivista | Manuscript+Campos+et+al.+2022 only clean copy.pdf |
| Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer’s disease | Sarah Macedo Vaz, Matheus de Freitas Silva, Graziella dos Reis Rosa Franco, Marcos Jorge R. Guima...raes, Fernanda Motta R. da Silva, Newton Gonçalves Castro, Isabella Alvim Guedes, Laurent E. Dardenne, Marina Amaral Alves, Rafael Garrett da Costa, Gabriela Beserra Pinheiro, Letícia Germino Veras, Marcia Renata Mortari, Letizia Pruccoli, Andrea Tarozzi, Claudio ´ Viegas Jr. | 2022-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Accepted manuscript_TAROZZI Andrea.pdf |
| Development of new extracts of crocus sativus l. By-product from two different italian regions as new potential active ingredient in cosmetic formulations | Gigliobianco M.R.; Cortese M.; Peregrina D.V.; Villa C.; Lupidi G.; Pruccoli L.; Angeloni C.; Tar...ozzi A.; Censi R.; Di Martino P. | 2021-01-01 | COSMETICS | - | 1.01 Articolo in rivista | Cosmetics 8-2-2021.pdf |
| Dysregulation of long non-coding RNAs in neuroinflammation: characterization of LINC00520 and its possible role in Parkinson's disease | Martina Fazzina, Letizia Pruccoli, Andrea Tarozzi, Francesca Massenzio, Barbara Monti, Davide Mae...stri, Matteo Bergonzoni, Flavia Frabetti, Raffaella Casadei | 2021-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Esculetin provides neuroprotection against mutant huntingtin-induced toxicity in huntington’s disease models | Pruccoli L.; Breda C.; Teti G.; Falconi M.; Giorgini F.; Tarozzi A. | 2021-01-01 | PHARMACEUTICALS | - | 1.01 Articolo in rivista | Pharmaceuticals 14 2021.pdf; pharmaceuticals-14-01044-s001.zip |
| New antioxidant ingredients from brewery by-products for cosmetic formulations | Censi R.; Peregrina D.V.; Gigliobianco M.R.; Lupidi G.; Angeloni C.; Pruccoli L.; Tarozzi A.; Di ...Martino P. | 2021-01-01 | COSMETICS | - | 1.01 Articolo in rivista | Cosmetics 8 2021.pdf |
| Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases | Cindy Juliet Cristancho Ortiz; Caio Miranda Damasio; Letizia Pruccoli; Nathália Fonseca Nadur; Lu...ciana Luiza de Azevedo; Isabella Alvim Guedes; Laurent Emmanuel Dardenne; Arthur Eugen Kümmerle; Andrea Tarozzi; Claudio Viegas Jr | 2020-01-01 | NEUROCHEMICAL RESEARCH | - | 1.01 Articolo in rivista | - |
| Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease | Matheus de Freitas Silva; Ellen Tardelli Lima; Letizia Pruccoli; Newton G Castro; Marcos Jorge R ...Guimarães; Fernanda M R da Silva; Nathalia Fonseca Nadur; Luciana Luiz de Azevedo; Arthur Eugen Kümmerle; Isabella Alvim Guedes; Laurent Emmanuel Dardenne; Vanessa Silva Gontijo; Andrea Tarozzi; Claudio Viegas | 2020-01-01 | MOLECULES | - | 1.01 Articolo in rivista | molecules-25-03165.pdf |
| Esculetin as a Bifunctional Antioxidant Prevents and Counteracts the Oxidative Stress and Neuronal Death Induced by Amyloid Protein in SH-SY5Y Cells | Pruccoli, L; Morroni, F; Sita, G; Hrelia, P; Tarozzi, A | 2020-01-01 | ANTIOXIDANTS | - | 1.01 Articolo in rivista | antioxidants-09-00551.pdf; Figure S1.docx; Figure S2.docx |
| Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease | Rita Maria Concetta Di Martino; Letizia Pruccoli; Alessandra Bisi; Silvia Gobbi; Angela Rampa; An...a Martinez; Concepción Pérez; Loreto Martinez-Gonzalez; Maria Paglione; Elia Di Schiavi; Francesca Seghetti; Andrea Tarozzi; Federica Belluti | 2020-01-01 | ACS CHEMICAL NEUROSCIENCE | - | 1.01 Articolo in rivista | Nrf2 Inducer for the Treatment of Parkinson’s Disease.pdf; cn0c00363_si_001.pdf |
| Optimization of the Extraction from Spent Coffee Grounds Using the Desirability Approach | Maria Rosa Gigliobianco; Barbara Campisi; Dolores Vargas Peregrina; Roberta Censi; Gulzhan Khamit...ova; Simone Angeloni; Giovanni Caprioli; Marco Zannotti; Stefano Ferraro; Rita Giovannetti; Cristina Angeloni; Giulio Lupidi; Letizia Pruccoli; Andrea Tarozzi; Dario Voinovich; Piera Di Martino | 2020-01-01 | ANTIOXIDANTS | - | 1.01 Articolo in rivista | antioxidants-09-00370.pdf |
| Curcumin and Heme Oxygenase: Neuroprotection and Beyond | Emanuela Mhillaj, Andrea Tarozzi, Letizia Pruccoli, Vincenzo Cuomo, Luigia Trabace, Cesare Mancuso | 2019-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-Tarozzi 2019.pdf |
| Design and synthesis of H 2 S-donor hybrids: A new treatment for Alzheimer's disease? | Simona Sestito, Letizia Pruccoli, Massimiliano Runfola, Valentina Citi, Alma Martelli, Giuseppe S...accomanni, Vincenzo Calderone, Andrea Tarozzi, Simona Rapposell | 2019-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |