PRUCCOLI, LETIZIA
 Distribuzione geografica
Continente #
AS - Asia 2.619
NA - Nord America 2.383
EU - Europa 2.020
SA - Sud America 177
AF - Africa 157
OC - Oceania 11
Continente sconosciuto - Info sul continente non disponibili 2
Totale 7.369
Nazione #
US - Stati Uniti d'America 2.319
IT - Italia 893
CN - Cina 680
VN - Vietnam 632
SG - Singapore 617
DE - Germania 202
GB - Regno Unito 194
SE - Svezia 160
HK - Hong Kong 149
BD - Bangladesh 140
BR - Brasile 128
IN - India 109
FR - Francia 93
KR - Corea 93
NL - Olanda 92
RU - Federazione Russa 66
FI - Finlandia 60
IE - Irlanda 59
CA - Canada 35
JP - Giappone 35
TG - Togo 35
CI - Costa d'Avorio 34
BG - Bulgaria 33
ZA - Sudafrica 33
ID - Indonesia 28
SC - Seychelles 28
TW - Taiwan 26
ES - Italia 22
AR - Argentina 21
PH - Filippine 20
AT - Austria 17
BE - Belgio 16
IQ - Iraq 15
MX - Messico 14
PL - Polonia 13
UA - Ucraina 13
EE - Estonia 12
HR - Croazia 12
JO - Giordania 12
PT - Portogallo 11
TR - Turchia 11
CH - Svizzera 10
GR - Grecia 10
AU - Australia 9
CZ - Repubblica Ceca 9
TH - Thailandia 9
EC - Ecuador 8
EG - Egitto 8
CL - Cile 7
NG - Nigeria 7
PK - Pakistan 7
MY - Malesia 6
IR - Iran 5
LT - Lituania 5
BO - Bolivia 4
DK - Danimarca 4
MA - Marocco 4
UZ - Uzbekistan 4
AE - Emirati Arabi Uniti 3
CO - Colombia 3
CR - Costa Rica 3
DO - Repubblica Dominicana 3
KZ - Kazakistan 3
RO - Romania 3
SA - Arabia Saudita 3
VE - Venezuela 3
AZ - Azerbaigian 2
DZ - Algeria 2
GT - Guatemala 2
HU - Ungheria 2
JM - Giamaica 2
LB - Libano 2
LK - Sri Lanka 2
MD - Moldavia 2
NZ - Nuova Zelanda 2
PY - Paraguay 2
TN - Tunisia 2
A1 - Anonimo 1
AM - Armenia 1
BS - Bahamas 1
BY - Bielorussia 1
DM - Dominica 1
ET - Etiopia 1
GH - Ghana 1
HN - Honduras 1
KE - Kenya 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LI - Liechtenstein 1
LU - Lussemburgo 1
LV - Lettonia 1
MT - Malta 1
NI - Nicaragua 1
NP - Nepal 1
OM - Oman 1
PA - Panama 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
UY - Uruguay 1
Totale 7.367
Città #
Singapore 423
Ashburn 296
Bologna 288
Hefei 204
Southend 154
Chandler 143
San Jose 140
Fairfield 136
Hong Kong 135
Ho Chi Minh City 133
Hanoi 127
Santa Clara 118
Dong Ket 99
Council Bluffs 85
Seoul 77
Beijing 73
Woodbridge 73
Houston 72
New York 66
Ann Arbor 63
Seattle 62
Los Angeles 60
Cambridge 56
Wilmington 56
Redmond 54
Boardman 53
Dublin 53
Milan 51
Princeton 50
Helsinki 47
Lauterbourg 38
Lomé 35
Abidjan 34
Dallas 34
Sofia 33
Buffalo 31
San Giorgio di Piano 30
Tokyo 29
Da Nang 26
Rimini 26
Rome 22
Berlin 21
Jakarta 21
Johannesburg 20
San Diego 20
Cesena 19
Nanjing 19
Frankfurt am Main 18
Portogruaro 18
Bremen 17
São Paulo 17
Bengaluru 16
Brussels 16
Hyderabad 16
Forlì 14
Haiphong 14
Amsterdam 13
Bari 13
Chicago 13
Nuremberg 13
Phoenix 13
Redondo Beach 13
Westminster 13
Amman 12
Cervia 12
Florence 12
Guangzhou 12
Munich 12
Biên Hòa 11
Boydton 11
Redwood City 11
Des Moines 10
Falkenstein 10
Hải Dương 10
Lappeenranta 10
Modena 10
Stockholm 10
Naples 9
Salt Lake City 9
Shenyang 9
Toronto 9
Turin 9
Jinan 8
Kaohsiung 8
Montreal 8
Orem 8
Padova 8
Saint Petersburg 8
Shanghai 8
Thái Nguyên 8
Venezia 8
Atlanta 7
Hangzhou 7
London 7
Tongling 7
Verona 7
Vienna 7
Baghdad 6
Castelfranco Emilia 6
Changsha 6
Totale 4.472
Nome #
Comparison of Adaptive Neuroprotective Mechanisms of Sulforaphane and its Interconversion Product Erucin in in Vitro and in Vivo Models of Parkinson's Disease 371
Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment 340
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease 339
Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives 297
Dysregulation of long non-coding RNAs in neuroinflammation: characterization of LINC00520 and its possible role in Parkinson's disease 291
Heat stress as a potential risk factor for vitamin D deficiency 250
PROTAC-INDUCED GLYCOGEN SYNTHASE KINASE 3B DEGRADATION 238
Antioxidant and Neuroprotective Effects of Fucoxanthin and Its Metabolite Fucoxanthinol: A Comparative In Vitro Study 230
Exploiting the chalcone scaffold to develop multifunctional agents for Alzheimer’s disease 215
PQM130, a novel feruloyl-donepezil hybrid compound, effectively ameliorates the cognitive impairments and pathology in a mouse model of Alzheimer's disease 213
Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold 208
The Keap1/Nrf2-ARE pathway as a pharmacological target for chalcones 202
Naturally inspired molecules as multifunctional agents for Alzheimer's disease treatment 199
Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease 192
Design, synthesis and evaluation of novel feruloyl-donepezil hybrids as potential multitarget drugs for the treatment of Alzheimer's disease 190
Esculetin as a Bifunctional Antioxidant Prevents and Counteracts the Oxidative Stress and Neuronal Death Induced by Amyloid Protein in SH-SY5Y Cells 188
Antioxidant and Anti-Melanogenesis Effects of Teucrium chamaedrys L. Cell Suspension Extract and Its Main Phenylethanoid Glycoside in B16-F10 Cells 183
Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates 180
Synthesis and pharmacological evaluation of novel N-aryl-cinnamoyl-hydrazone hybrids designed as neuroprotective agents for the treatment of Parkinson’s disease 179
Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer’s disease 175
Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases 174
Design, synthesis, and biological evaluation of new thalidomide–donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation 165
Protective effects of chrysin against the neurotoxicity induced by aluminium: In vitro and in vivo studies 157
Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate. 155
Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease 149
A novel arylpiperazine derivative (LQFM181) protects against neurotoxicity induced by 3- nitropropionic acid in in vitro and in vivo models 146
null 141
Pyridinylimidazoles as GSK3β Inhibitors: The Impact of Tautomerism on Compound Activity via Water Networks 141
Optimization of the Extraction from Spent Coffee Grounds Using the Desirability Approach 130
Chalcone-based carbamates for Alzheimer's disease treatment 129
Esculetin provides neuroprotection against mutant huntingtin-induced toxicity in huntington’s disease models 129
Curcumin and Heme Oxygenase: Neuroprotection and Beyond 125
null 118
Development of new extracts of crocus sativus l. By-product from two different italian regions as new potential active ingredient in cosmetic formulations 118
New antioxidant ingredients from brewery by-products for cosmetic formulations 115
Glycosylation of chrysin with β-d-glucose tetraacetate (LQFM280) enhances its in vitro and in vivo neuroprotective effects against the toxicity induced by 3-nitropropionic acid 113
Quinazoline based α1-adrenoreceptor antagonists with potent antiproliferative activity in human prostate cancer cell lines 108
Rational optimization of D3R/GSK-3β dual target-directed ligands as potential treatment for bipolar disorder: Design, synthesis, X-ray crystallography, molecular dynamics simulations, in vitro ADME, and in vivo pharmacokinetic studies 102
Influence of Guanine-Based Purines on the Oxidoreductive Reactions Involved in Normal or Altered Brain Functions 100
Antioxidant and neuroprotective effects of ubiquinol diacetate: Insights from SH-SY5Y cell line and Caenorhabditis elegans models of Parkinson's disease 85
Exploring the anti-inflammatory activity of sulforaphane metabolites 84
null 79
Effetti Antiossidanti e Antinfiammatori del Nutraceutico Sulforafano e dei suoi Metaboliti: uno Studio Comparativo in Modelli in vitro 73
Targeting Alzheimer’s disease neurotoxicity by functionalization of the chalcone scaffold 67
null 52
Design and synthesis of H 2 S-donor hybrids: A new treatment for Alzheimer's disease? 29
Totale 7.664
Categoria #
all - tutte 21.472
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 21.472


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022691 34 8 32 45 52 45 23 83 69 95 119 86
2022/2023645 64 76 27 75 68 51 41 51 104 12 51 25
2023/2024559 25 54 54 70 31 95 38 70 15 32 35 40
2024/20251.264 76 120 99 75 194 65 112 71 37 102 113 200
2025/20263.316 225 323 258 216 262 150 341 177 607 293 205 259
2026/202724 24 0 0 0 0 0 0 0 0 0 0 0
Totale 7.664