TAROZZI, ANDREA
TAROZZI, ANDREA
DIPARTIMENTO DI SCIENZE PER LA QUALITA' DELLA VITA
Docenti di ruolo di Ia fascia
Chrysin bonded to β-d-glucose tetraacetate enhances its protective effects against the neurotoxicity induced by aluminum in Swiss mice
2024 Victor Ifeanyi Okoh, Hericles Mesquita Campos, Pâmela Yasmin de Oliveira Ferreira, Robbert Mota Pereira, Yohanny Souza Silva, Evilanna Lima Arruda, Barbara Pagliarani, Gerlon de Almeida Ribeiro Oliveira, Luciano Morais Lião, Gabriel Franco Dos Santos, Boniek Gontijo Vaz, José Ricardo Sabino, Fernanda Cristina Alcantara Dos Santos, Elson Alves Costa, Andrea Tarozzi, Ricardo Menegatti, Paulo César Ghedini
First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer’s Disease
2024 Santini A.; Tassinari E.; Poeta E.; Loi M.; Ciani E.; Trazzi S.; Piccarducci R.; Daniele S.; Martini C.; Pagliarani B.; Tarozzi A.; Bersani M.; Spyrakis F.; Danková D.; Olsen C.A.; Soldati R.; Tumiatti V.; Montanari S.; De Simone A.; Milelli A.
Synthesis and pharmacological evaluation of novel N-aryl-cinnamoyl-hydrazone hybrids designed as neuroprotective agents for the treatment of Parkinson’s disease
2024 Matheus de Freitas Silva, Cindy Juliet Cristancho Ortiz, Letícia Ferreira Coelho, Letizia Pruccoli, Barbara Pagliarani, Leonardo Pisani, Marco Catto, Giulio Poli, Tiziano Tuccinardi, Fabiana Cardoso Vilela, Alexandre Giusti-Paiva, Marina Amaral Alves, Hygor M. Ribeiro de Souza, Andrea Tarozzi, Vanessa Silva Gontijo, Claudio Viegas Jr.
Heat stress as a potential risk factor for vitamin D deficiency
2023 Balducci M.; Pruccoli L.; Tarozzi A.
Neuroprotection by Drugs, Nutraceuticals and Physical Activity
2023 Tarozzi A.; Angeloni C.
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease
2023 Guardigni M.; Pruccoli L.; Santini A.; Simone A.D.; Bersani M.; Spyrakis F.; Frabetti F.; Uliassi E.; Andrisano V.; Pagliarani B.; Fernández-Gómez P.; Palomo V.; Bolognesi M.L.; Tarozzi A.; Milelli A.
Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold
2023 De Lorenzi, Ersilia; Seghetti, Francesca; Tarozzi, Andrea; Pruccoli, Letizia; Contardi, Cecilia; Serra, Massimo; Bisi, Alessandra; Gobbi, Silvia; Vistoli, Giulio; Gervasoni, Silvia; Argentini, Carla; Ghirardo, Giulia; Guarato, Giulia; Orso, Genny; Belluti, Federica; Di Martino, Rita Maria Concetta; Zusso, Morena
Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors
2022 Andreev S.; Pantsar T.; Tesch R.; Kahlke N.; El-Gokha A.; Ansideri F.; Gratz L.; Romasco J.; Sita G.; Geibel C.; Lammerhofer M.; Tarozzi A.; Knapp S.; Laufer S.A.; Koch P.
Design, synthesis, and biological evaluation of new thalidomide–donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation
2022 Cindy Juliet Cristancho Ortiz, Matheus de Freitas Silva, Letizia Pruccoli, Nathália Fonseca Nadur, Luciana Luíza de Azevedo, Arthur Eugen Kümmerle, Isabella Alvim Guedes, Laurent Emmanuel Dardenne, Luiz Felipe Leomil Coelho, Marcos J. Guimarães, Fernanda M. R. da Silva, Newton Castro, Vanessa Silva Gontijo, Viviana C. T. Rojas, Merelym Ketterym de Oliveira, Fabiana Cardoso Vilela, Alexandre Giusti-Paiva, Gisele Barbosa, Lídia Moreira Lima, Gabriela Beserra Pinheiro, Letícia Germino Veras, Márcia Renata Mortari, Andrea Tarozzi, Claudio Viegas Jr
PROTAC-INDUCED GLYCOGEN SYNTHASE KINASE 3B DEGRADATION
2022 Santini, A.; Pruccoli, L.; Guardigni, M.; De Simone, A.; Spyrakis, F.; Frabetti, F.; Andrisano, V.; Bolognesi, M. L.; Tarozzi, A.; Milelli, A.
Protective effects of chrysin against the neurotoxicity induced by aluminium: In vitro and in vivo studies
2022 Campos H.M.; da Costa M.; da Silva Moreira L.K.; da Silva Neri H.F.; Branco da Silva C.R.; Pruccoli L.; dos Santos F.C.A.; Costa E.A.; Tarozzi A.; Ghedini P.C.
Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer’s disease
2022 Sarah Macedo Vaz, Matheus de Freitas Silva, Graziella dos Reis Rosa Franco, Marcos Jorge R. Guimaraes, Fernanda Motta R. da Silva, Newton Gonçalves Castro, Isabella Alvim Guedes, Laurent E. Dardenne, Marina Amaral Alves, Rafael Garrett da Costa, Gabriela Beserra Pinheiro, Letícia Germino Veras, Marcia Renata Mortari, Letizia Pruccoli, Andrea Tarozzi, Claudio ´ Viegas Jr.
Development of new extracts of crocus sativus l. By-product from two different italian regions as new potential active ingredient in cosmetic formulations
2021 Gigliobianco M.R.; Cortese M.; Peregrina D.V.; Villa C.; Lupidi G.; Pruccoli L.; Angeloni C.; Tarozzi A.; Censi R.; Di Martino P.
Dysregulation of long non-coding RNAs in neuroinflammation: characterization of LINC00520 and its possible role in Parkinson's disease
2021 Martina Fazzina, Letizia Pruccoli, Andrea Tarozzi, Francesca Massenzio, Barbara Monti, Davide Maestri, Matteo Bergonzoni, Flavia Frabetti, Raffaella Casadei
Esculetin provides neuroprotection against mutant huntingtin-induced toxicity in huntington’s disease models
2021 Pruccoli L.; Breda C.; Teti G.; Falconi M.; Giorgini F.; Tarozzi A.
New antioxidant ingredients from brewery by-products for cosmetic formulations
2021 Censi R.; Peregrina D.V.; Gigliobianco M.R.; Lupidi G.; Angeloni C.; Pruccoli L.; Tarozzi A.; Di Martino P.
Urinary Markers and Chronic Effect of Physical Exercise
2021 Vittori L.N.; Romasco J.; Tarozzi A.; Maietta Latessa P.
Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases
2020 Cindy Juliet Cristancho Ortiz; Caio Miranda Damasio; Letizia Pruccoli; Nathália Fonseca Nadur; Luciana Luiza de Azevedo; Isabella Alvim Guedes; Laurent Emmanuel Dardenne; Arthur Eugen Kümmerle; Andrea Tarozzi; Claudio Viegas Jr
Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease
2020 Matheus de Freitas Silva; Ellen Tardelli Lima; Letizia Pruccoli; Newton G Castro; Marcos Jorge R Guimarães; Fernanda M R da Silva; Nathalia Fonseca Nadur; Luciana Luiz de Azevedo; Arthur Eugen Kümmerle; Isabella Alvim Guedes; Laurent Emmanuel Dardenne; Vanessa Silva Gontijo; Andrea Tarozzi; Claudio Viegas
Discovery and evaluation of enantiopure 9H-pyrimido[4,5‐b]indoles as nanomolar GSK‐3β inhibitors with improved metabolic stability
2020 Andreev S.; Pantsar T.; El-gokha A.; Ansideri F.; Kudolo M.; Anton D.B.; Sita G.; Romasco J.; Geibel C.; Lammerhofer M.; Goettert M.I.; Tarozzi A.; Laufer S.A.; Koch P.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Chrysin bonded to β-d-glucose tetraacetate enhances its protective effects against the neurotoxicity induced by aluminum in Swiss mice | Victor Ifeanyi Okoh, Hericles Mesquita Campos, Pâmela Yasmin de Oliveira Ferreira, Robbert Mota P...ereira, Yohanny Souza Silva, Evilanna Lima Arruda, Barbara Pagliarani, Gerlon de Almeida Ribeiro Oliveira, Luciano Morais Lião, Gabriel Franco Dos Santos, Boniek Gontijo Vaz, José Ricardo Sabino, Fernanda Cristina Alcantara Dos Santos, Elson Alves Costa, Andrea Tarozzi, Ricardo Menegatti, Paulo César Ghedini | 2024-01-01 | JOURNAL OF PHARMACY AND PHARMACOLOGY | - | 1.01 Articolo in rivista | Postprint.pdf |
| First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer’s Disease | Santini A.; Tassinari E.; Poeta E.; Loi M.; Ciani E.; Trazzi S.; Piccarducci R.; Daniele S.; Mart...ini C.; Pagliarani B.; Tarozzi A.; Bersani M.; Spyrakis F.; Danková D.; Olsen C.A.; Soldati R.; Tumiatti V.; Montanari S.; De Simone A.; Milelli A. | 2024-01-01 | ACS CHEMICAL NEUROSCIENCE | - | 1.01 Articolo in rivista | - |
| Synthesis and pharmacological evaluation of novel N-aryl-cinnamoyl-hydrazone hybrids designed as neuroprotective agents for the treatment of Parkinson’s disease | Matheus de Freitas Silva, Cindy Juliet Cristancho Ortiz, Letícia Ferreira Coelho, Letizia Pruccol...i, Barbara Pagliarani, Leonardo Pisani, Marco Catto, Giulio Poli, Tiziano Tuccinardi, Fabiana Cardoso Vilela, Alexandre Giusti-Paiva, Marina Amaral Alves, Hygor M. Ribeiro de Souza, Andrea Tarozzi, Vanessa Silva Gontijo, Claudio Viegas Jr. | 2024-01-01 | BIOORGANIC CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Heat stress as a potential risk factor for vitamin D deficiency | Balducci M.; Pruccoli L.; Tarozzi A. | 2023-01-01 | MEDICAL HYPOTHESES | - | 1.01 Articolo in rivista | Revised manuscript.pdf |
| Neuroprotection by Drugs, Nutraceuticals and Physical Activity | Tarozzi A.; Angeloni C. | 2023-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-24-03176.pdf |
| PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease | Guardigni M.; Pruccoli L.; Santini A.; Simone A.D.; Bersani M.; Spyrakis F.; Frabetti F.; Uliassi... E.; Andrisano V.; Pagliarani B.; Fernández-Gómez P.; Palomo V.; Bolognesi M.L.; Tarozzi A.; Milelli A. | 2023-01-01 | ACS CHEMICAL NEUROSCIENCE | - | 1.01 Articolo in rivista | acschemneuro.3c00096.pdf; cn3c00096_si_001.pdf |
| Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold | De Lorenzi, Ersilia; Seghetti, Francesca; Tarozzi, Andrea; Pruccoli, Letizia; Contardi, Cecilia; ...Serra, Massimo; Bisi, Alessandra; Gobbi, Silvia; Vistoli, Giulio; Gervasoni, Silvia; Argentini, Carla; Ghirardo, Giulia; Guarato, Giulia; Orso, Genny; Belluti, Federica; Di Martino, Rita Maria Concetta; Zusso, Morena | 2023-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold.pdf |
| Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors | Andreev S.; Pantsar T.; Tesch R.; Kahlke N.; El-Gokha A.; Ansideri F.; Gratz L.; Romasco J.; Sita... G.; Geibel C.; Lammerhofer M.; Tarozzi A.; Knapp S.; Laufer S.A.; Koch P. | 2022-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | J Med Chem 2022.pdf; jm0c02146_si_001.pdf |
| Design, synthesis, and biological evaluation of new thalidomide–donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation | Cindy Juliet Cristancho Ortiz, Matheus de Freitas Silva, Letizia Pruccoli, Nathália Fonseca Nadur..., Luciana Luíza de Azevedo, Arthur Eugen Kümmerle, Isabella Alvim Guedes, Laurent Emmanuel Dardenne, Luiz Felipe Leomil Coelho, Marcos J. Guimarães, Fernanda M. R. da Silva, Newton Castro, Vanessa Silva Gontijo, Viviana C. T. Rojas, Merelym Ketterym de Oliveira, Fabiana Cardoso Vilela, Alexandre Giusti-Paiva, Gisele Barbosa, Lídia Moreira Lima, Gabriela Beserra Pinheiro, Letícia Germino Veras, Márcia Renata Mortari, Andrea Tarozzi, Claudio Viegas Jr | 2022-01-01 | RSC MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Manuscript RSC TAROZZI Andrea.pdf |
| PROTAC-INDUCED GLYCOGEN SYNTHASE KINASE 3B DEGRADATION | Santini, A.; Pruccoli, L.; Guardigni, M.; De Simone, A.; Spyrakis, F.; Frabetti, F.; Andrisano, V....; Bolognesi, M. L.; Tarozzi, A.; Milelli, A. | 2022-01-01 | - | - | 4.03 Poster | - |
| Protective effects of chrysin against the neurotoxicity induced by aluminium: In vitro and in vivo studies | Campos H.M.; da Costa M.; da Silva Moreira L.K.; da Silva Neri H.F.; Branco da Silva C.R.; Prucco...li L.; dos Santos F.C.A.; Costa E.A.; Tarozzi A.; Ghedini P.C. | 2022-01-01 | TOXICOLOGY | - | 1.01 Articolo in rivista | Manuscript+Campos+et+al.+2022 only clean copy.pdf |
| Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer’s disease | Sarah Macedo Vaz, Matheus de Freitas Silva, Graziella dos Reis Rosa Franco, Marcos Jorge R. Guima...raes, Fernanda Motta R. da Silva, Newton Gonçalves Castro, Isabella Alvim Guedes, Laurent E. Dardenne, Marina Amaral Alves, Rafael Garrett da Costa, Gabriela Beserra Pinheiro, Letícia Germino Veras, Marcia Renata Mortari, Letizia Pruccoli, Andrea Tarozzi, Claudio ´ Viegas Jr. | 2022-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Accepted manuscript_TAROZZI Andrea.pdf |
| Development of new extracts of crocus sativus l. By-product from two different italian regions as new potential active ingredient in cosmetic formulations | Gigliobianco M.R.; Cortese M.; Peregrina D.V.; Villa C.; Lupidi G.; Pruccoli L.; Angeloni C.; Tar...ozzi A.; Censi R.; Di Martino P. | 2021-01-01 | COSMETICS | - | 1.01 Articolo in rivista | Cosmetics 8-2-2021.pdf |
| Dysregulation of long non-coding RNAs in neuroinflammation: characterization of LINC00520 and its possible role in Parkinson's disease | Martina Fazzina, Letizia Pruccoli, Andrea Tarozzi, Francesca Massenzio, Barbara Monti, Davide Mae...stri, Matteo Bergonzoni, Flavia Frabetti, Raffaella Casadei | 2021-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Esculetin provides neuroprotection against mutant huntingtin-induced toxicity in huntington’s disease models | Pruccoli L.; Breda C.; Teti G.; Falconi M.; Giorgini F.; Tarozzi A. | 2021-01-01 | PHARMACEUTICALS | - | 1.01 Articolo in rivista | Pharmaceuticals 14 2021.pdf; pharmaceuticals-14-01044-s001.zip |
| New antioxidant ingredients from brewery by-products for cosmetic formulations | Censi R.; Peregrina D.V.; Gigliobianco M.R.; Lupidi G.; Angeloni C.; Pruccoli L.; Tarozzi A.; Di ...Martino P. | 2021-01-01 | COSMETICS | - | 1.01 Articolo in rivista | Cosmetics 8 2021.pdf |
| Urinary Markers and Chronic Effect of Physical Exercise | Vittori L.N.; Romasco J.; Tarozzi A.; Maietta Latessa P. | 2021-01-01 | - | Humana Press Inc. | 2.01 Capitolo / saggio in libro | - |
| Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases | Cindy Juliet Cristancho Ortiz; Caio Miranda Damasio; Letizia Pruccoli; Nathália Fonseca Nadur; Lu...ciana Luiza de Azevedo; Isabella Alvim Guedes; Laurent Emmanuel Dardenne; Arthur Eugen Kümmerle; Andrea Tarozzi; Claudio Viegas Jr | 2020-01-01 | NEUROCHEMICAL RESEARCH | - | 1.01 Articolo in rivista | - |
| Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease | Matheus de Freitas Silva; Ellen Tardelli Lima; Letizia Pruccoli; Newton G Castro; Marcos Jorge R ...Guimarães; Fernanda M R da Silva; Nathalia Fonseca Nadur; Luciana Luiz de Azevedo; Arthur Eugen Kümmerle; Isabella Alvim Guedes; Laurent Emmanuel Dardenne; Vanessa Silva Gontijo; Andrea Tarozzi; Claudio Viegas | 2020-01-01 | MOLECULES | - | 1.01 Articolo in rivista | molecules-25-03165.pdf |
| Discovery and evaluation of enantiopure 9H-pyrimido[4,5‐b]indoles as nanomolar GSK‐3β inhibitors with improved metabolic stability | Andreev S.; Pantsar T.; El-gokha A.; Ansideri F.; Kudolo M.; Anton D.B.; Sita G.; Romasco J.; Gei...bel C.; Lammerhofer M.; Goettert M.I.; Tarozzi A.; Laufer S.A.; Koch P. | 2020-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | 21 Int J Mol Sci 2020.pdf |