TAROZZI, ANDREA
TAROZZI, ANDREA
QUVI - DIPARTIMENTO DI SCIENZE PER LA QUALITA' DELLA VITA
Docenti di ruolo di Ia fascia
Glycosylation of chrysin with β-d-glucose tetraacetate (LQFM280) enhances its in vitro and in vivo neuroprotective effects against the toxicity induced by 3-nitropropionic acid
2025 Pereira, R. M.; Campos, H. M.; de Oliveira Ferreira, P. Y.; Uchenna, N.; Silva, Y. S.; Okoh, V. I.; Pruccoli, L.; Arruda, E. L.; Liao, L. M.; Mota, P. A. A.; Leite, J. A.; de Castro Georg, R.; Damatta, D.; dos Santos, F. C. A.; Costa, E. A.; Tarozzi, A.; Menegatti, R.; Ghedini, P. C.
A novel arylpiperazine derivative (LQFM181) protects against neurotoxicity induced by 3- nitropropionic acid in in vitro and in vivo models
2024 Mesquita Campos, Hericles; Mota Pereira, Robbert; Yasmin de Oliveira Ferreira, Pamela; Uchenna, Nkaa; Rio Branco da Silva, Cínthia; Pruccoli, Letizia; Sanz, German; Ferreira Rodrigues, Marcella; Gontijo Vaz, Boniek; Gonçalves Rivello, Barbara; Luís Batista da Rocha, Andre; Silva de Carvalho, Flavio; de Almeida Ribeiro Oliveira, Gerlon; Morais Liao, Luciano; de Castro Georg, Raphaela; Alves Leite, Jacqueline; Cristina Alcantara dos Santos, Fernanda; Alves Costa, Elson; Menegatti, Ricardo; Tarozzi, Andrea; Cesar Ghedini, Paulo
Antioxidant and Anti-Melanogenesis Effects of Teucrium chamaedrys L. Cell Suspension Extract and Its Main Phenylethanoid Glycoside in B16-F10 Cells
2024 Pruccoli, Letizia; Nicolini, Benedetta; Lianza, Mariacaterina; Teti, Gabriella; Falconi, Mirella; Tarozzi, Andrea; Antognoni, Fabiana
Antioxidant and Neuroprotective Effects of Fucoxanthin and Its Metabolite Fucoxanthinol: A Comparative In Vitro Study
2024 Pruccoli, Letizia; Balducci, Martina; Pagliarani, Barbara; Tarozzi, Andrea
Chrysin bonded to β-d-glucose tetraacetate enhances its protective effects against the neurotoxicity induced by aluminum in Swiss mice
2024 Ifeanyi Okoh, Victor; Mesquita Campos, Hericles; Yasmin de Oliveira Ferreira, Pâmela; Mota Pereira, Robbert; Souza Silva, Yohanny; Lima Arruda, Evilanna; Pagliarani, Barbara; de Almeida Ribeiro Oliveira, Gerlon; Morais Lião, Luciano; Franco Dos Santos, Gabriel; Gontijo Vaz, Boniek; Ricardo Sabino, José; Cristina Alcantara Dos Santos, Fernanda; Alves Costa, Elson; Tarozzi, Andrea; Menegatti, Ricardo; César Ghedini, Paulo
Erucin, a Natural Isothiocyanate, Prevents Polyglutamine-Induced Toxicity in Caenorhabditis elegans via aak-2/AMPK and daf-16/FOXO Signaling
2024 Balducci, M.; Perez, J. T.; del Rio, C. T.; Perez, M. C.; Carranza, A. D. V.; Gomez Escribano, A. P.; Vazquez-Manrique, R. P.; Tarozzi, A.
First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer’s Disease
2024 Santini A.; Tassinari E.; Poeta E.; Loi M.; Ciani E.; Trazzi S.; Piccarducci R.; Daniele S.; Martini C.; Pagliarani B.; Tarozzi A.; Bersani M.; Spyrakis F.; Danková D.; Olsen C.A.; Soldati R.; Tumiatti V.; Montanari S.; De Simone A.; Milelli A.
Synthesis and pharmacological evaluation of novel N-aryl-cinnamoyl-hydrazone hybrids designed as neuroprotective agents for the treatment of Parkinson’s disease
2024 de Freitas Silva, Matheus; Juliet Cristancho Ortiz, Cindy; Ferreira Coelho, Letícia; Pruccoli, Letizia; Pagliarani, Barbara; Pisani, Leonardo; Catto, Marco; Poli, Giulio; Tuccinardi, Tiziano; Cardoso Vilela, Fabiana; Giusti-Paiva, Alexandre; Amaral Alves, Marina; Ribeiro de Souza, Hygor M.; Tarozzi, Andrea; Silva Gontijo, Vanessa; Jr., Claudio Viegas
Heat stress as a potential risk factor for vitamin D deficiency
2023 Balducci M.; Pruccoli L.; Tarozzi A.
Neuroprotection by Drugs, Nutraceuticals and Physical Activity
2023 Tarozzi A.; Angeloni C.
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease
2023 Guardigni M.; Pruccoli L.; Santini A.; Simone A.D.; Bersani M.; Spyrakis F.; Frabetti F.; Uliassi E.; Andrisano V.; Pagliarani B.; Fernández-Gómez P.; Palomo V.; Bolognesi M.L.; Tarozzi A.; Milelli A.
Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold
2023 De Lorenzi, Ersilia; Seghetti, Francesca; Tarozzi, Andrea; Pruccoli, Letizia; Contardi, Cecilia; Serra, Massimo; Bisi, Alessandra; Gobbi, Silvia; Vistoli, Giulio; Gervasoni, Silvia; Argentini, Carla; Ghirardo, Giulia; Guarato, Giulia; Orso, Genny; Belluti, Federica; Di Martino, Rita Maria Concetta; Zusso, Morena
Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors
2022 Andreev S.; Pantsar T.; Tesch R.; Kahlke N.; El-Gokha A.; Ansideri F.; Gratz L.; Romasco J.; Sita G.; Geibel C.; Lammerhofer M.; Tarozzi A.; Knapp S.; Laufer S.A.; Koch P.
Design, synthesis, and biological evaluation of new thalidomide–donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation
2022 Cindy Juliet Cristancho Ortiz, Matheus de Freitas Silva, Letizia Pruccoli, Nathália Fonseca Nadur, Luciana Luíza de Azevedo, Arthur Eugen Kümmerle, Isabella Alvim Guedes, Laurent Emmanuel Dardenne, Luiz Felipe Leomil Coelho, Marcos J. Guimarães, Fernanda M. R. da Silva, Newton Castro, Vanessa Silva Gontijo, Viviana C. T. Rojas, Merelym Ketterym de Oliveira, Fabiana Cardoso Vilela, Alexandre Giusti-Paiva, Gisele Barbosa, Lídia Moreira Lima, Gabriela Beserra Pinheiro, Letícia Germino Veras, Márcia Renata Mortari, Andrea Tarozzi, Claudio Viegas Jr
PROTAC-INDUCED GLYCOGEN SYNTHASE KINASE 3B DEGRADATION
2022 Santini, A.; Pruccoli, L.; Guardigni, M.; De Simone, A.; Spyrakis, F.; Frabetti, F.; Andrisano, V.; Bolognesi, M. L.; Tarozzi, A.; Milelli, A.
Protective effects of chrysin against the neurotoxicity induced by aluminium: In vitro and in vivo studies
2022 Campos H.M.; da Costa M.; da Silva Moreira L.K.; da Silva Neri H.F.; Branco da Silva C.R.; Pruccoli L.; dos Santos F.C.A.; Costa E.A.; Tarozzi A.; Ghedini P.C.
Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer’s disease
2022 Sarah Macedo Vaz, Matheus de Freitas Silva, Graziella dos Reis Rosa Franco, Marcos Jorge R. Guimaraes, Fernanda Motta R. da Silva, Newton Gonçalves Castro, Isabella Alvim Guedes, Laurent E. Dardenne, Marina Amaral Alves, Rafael Garrett da Costa, Gabriela Beserra Pinheiro, Letícia Germino Veras, Marcia Renata Mortari, Letizia Pruccoli, Andrea Tarozzi, Claudio ´ Viegas Jr.
Development of new extracts of crocus sativus l. By-product from two different italian regions as new potential active ingredient in cosmetic formulations
2021 Gigliobianco, M. R.; Cortese, M.; Peregrina, D. V.; Villa, C.; Lupidi, G.; Pruccoli, L.; Angeloni, C.; Tarozzi, A.; Censi, R.; Di Martino, P.
Dysregulation of long non-coding RNAs in neuroinflammation: characterization of LINC00520 and its possible role in Parkinson's disease
2021 Fazzina, Martina; Pruccoli, Letizia; Tarozzi, Andrea; Massenzio, Francesca; Monti, Barbara; Maestri, Davide; Bergonzoni, Matteo; Frabetti, Flavia; Casadei, Raffaella
Esculetin provides neuroprotection against mutant huntingtin-induced toxicity in huntington’s disease models
2021 Pruccoli L.; Breda C.; Teti G.; Falconi M.; Giorgini F.; Tarozzi A.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Glycosylation of chrysin with β-d-glucose tetraacetate (LQFM280) enhances its in vitro and in vivo neuroprotective effects against the toxicity induced by 3-nitropropionic acid | Pereira, R. M.; Campos, H. M.; de Oliveira Ferreira, P. Y.; Uchenna, N.; Silva, Y. S.; Okoh, V. I....; Pruccoli, L.; Arruda, E. L.; Liao, L. M.; Mota, P. A. A.; Leite, J. A.; de Castro Georg, R.; Damatta, D.; dos Santos, F. C. A.; Costa, E. A.; Tarozzi, A.; Menegatti, R.; Ghedini, P. C. | 2025-01-01 | NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY | - | 1.01 Articolo in rivista | - |
| A novel arylpiperazine derivative (LQFM181) protects against neurotoxicity induced by 3- nitropropionic acid in in vitro and in vivo models | Mesquita Campos, Hericles; Mota Pereira, Robbert; Yasmin de Oliveira Ferreira, Pamela; Uchenna, N...kaa; Rio Branco da Silva, Cínthia; Pruccoli, Letizia; Sanz, German; Ferreira Rodrigues, Marcella; Gontijo Vaz, Boniek; Gonçalves Rivello, Barbara; Luís Batista da Rocha, Andre; Silva de Carvalho, Flavio; de Almeida Ribeiro Oliveira, Gerlon; Morais Liao, Luciano; de Castro Georg, Raphaela; Alves Leite, Jacqueline; Cristina Alcantara dos Santos, Fernanda; Alves Costa, Elson; Menegatti, Ricardo; Tarozzi, Andrea; Cesar Ghedini, Paulo | 2024-01-01 | CHEMICO-BIOLOGICAL INTERACTIONS | - | 1.01 Articolo in rivista | Final Article not marked POSTPRINT.pdf |
| Antioxidant and Anti-Melanogenesis Effects of Teucrium chamaedrys L. Cell Suspension Extract and Its Main Phenylethanoid Glycoside in B16-F10 Cells | Pruccoli, Letizia; Nicolini, Benedetta; Lianza, Mariacaterina; Teti, Gabriella; Falconi, Mirella;... Tarozzi, Andrea; Antognoni, Fabiana | 2024-01-01 | PLANTS | - | 1.01 Articolo in rivista | plants-13-00808 (1).pdf; plants-2894275-supplementary.pdf |
| Antioxidant and Neuroprotective Effects of Fucoxanthin and Its Metabolite Fucoxanthinol: A Comparative In Vitro Study | Pruccoli, Letizia; Balducci, Martina; Pagliarani, Barbara; Tarozzi, Andrea | 2024-01-01 | CURRENT ISSUES IN MOLECULAR BIOLOGY | - | 1.01 Articolo in rivista | cimb-46-00357 (2).pdf; cimb-46-00357-s001.zip |
| Chrysin bonded to β-d-glucose tetraacetate enhances its protective effects against the neurotoxicity induced by aluminum in Swiss mice | Ifeanyi Okoh, Victor; Mesquita Campos, Hericles; Yasmin de Oliveira Ferreira, Pâmela; Mota Pereir...a, Robbert; Souza Silva, Yohanny; Lima Arruda, Evilanna; Pagliarani, Barbara; de Almeida Ribeiro Oliveira, Gerlon; Morais Lião, Luciano; Franco Dos Santos, Gabriel; Gontijo Vaz, Boniek; Ricardo Sabino, José; Cristina Alcantara Dos Santos, Fernanda; Alves Costa, Elson; Tarozzi, Andrea; Menegatti, Ricardo; César Ghedini, Paulo | 2024-01-01 | JOURNAL OF PHARMACY AND PHARMACOLOGY | - | 1.01 Articolo in rivista | Postprint.pdf |
| Erucin, a Natural Isothiocyanate, Prevents Polyglutamine-Induced Toxicity in Caenorhabditis elegans via aak-2/AMPK and daf-16/FOXO Signaling | Balducci, M.; Perez, J. T.; del Rio, C. T.; Perez, M. C.; Carranza, A. D. V.; Gomez Escribano, A.... P.; Vazquez-Manrique, R. P.; Tarozzi, A. | 2024-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-25-12220.pdf; ijms-25-12220-s001.zip |
| First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer’s Disease | Santini A.; Tassinari E.; Poeta E.; Loi M.; Ciani E.; Trazzi S.; Piccarducci R.; Daniele S.; Mart...ini C.; Pagliarani B.; Tarozzi A.; Bersani M.; Spyrakis F.; Danková D.; Olsen C.A.; Soldati R.; Tumiatti V.; Montanari S.; De Simone A.; Milelli A. | 2024-01-01 | ACS CHEMICAL NEUROSCIENCE | - | 1.01 Articolo in rivista | acs-cn.pdf |
| Synthesis and pharmacological evaluation of novel N-aryl-cinnamoyl-hydrazone hybrids designed as neuroprotective agents for the treatment of Parkinson’s disease | de Freitas Silva, Matheus; Juliet Cristancho Ortiz, Cindy; Ferreira Coelho, Letícia; Pruccoli, Le...tizia; Pagliarani, Barbara; Pisani, Leonardo; Catto, Marco; Poli, Giulio; Tuccinardi, Tiziano; Cardoso Vilela, Fabiana; Giusti-Paiva, Alexandre; Amaral Alves, Marina; Ribeiro de Souza, Hygor M.; Tarozzi, Andrea; Silva Gontijo, Vanessa; Jr., Claudio Viegas | 2024-01-01 | BIOORGANIC CHEMISTRY | - | 1.01 Articolo in rivista | Manuscript ridotto.pdf |
| Heat stress as a potential risk factor for vitamin D deficiency | Balducci M.; Pruccoli L.; Tarozzi A. | 2023-01-01 | MEDICAL HYPOTHESES | - | 1.01 Articolo in rivista | Revised manuscript.pdf |
| Neuroprotection by Drugs, Nutraceuticals and Physical Activity | Tarozzi A.; Angeloni C. | 2023-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-24-03176.pdf |
| PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease | Guardigni M.; Pruccoli L.; Santini A.; Simone A.D.; Bersani M.; Spyrakis F.; Frabetti F.; Uliassi... E.; Andrisano V.; Pagliarani B.; Fernández-Gómez P.; Palomo V.; Bolognesi M.L.; Tarozzi A.; Milelli A. | 2023-01-01 | ACS CHEMICAL NEUROSCIENCE | - | 1.01 Articolo in rivista | acschemneuro.3c00096.pdf |
| Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold | De Lorenzi, Ersilia; Seghetti, Francesca; Tarozzi, Andrea; Pruccoli, Letizia; Contardi, Cecilia; ...Serra, Massimo; Bisi, Alessandra; Gobbi, Silvia; Vistoli, Giulio; Gervasoni, Silvia; Argentini, Carla; Ghirardo, Giulia; Guarato, Giulia; Orso, Genny; Belluti, Federica; Di Martino, Rita Maria Concetta; Zusso, Morena | 2023-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold.pdf; 1-s2.0-S0223523423002635-mmc1.pdf |
| Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors | Andreev S.; Pantsar T.; Tesch R.; Kahlke N.; El-Gokha A.; Ansideri F.; Gratz L.; Romasco J.; Sita... G.; Geibel C.; Lammerhofer M.; Tarozzi A.; Knapp S.; Laufer S.A.; Koch P. | 2022-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | J Med Chem 2022.pdf |
| Design, synthesis, and biological evaluation of new thalidomide–donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation | Cindy Juliet Cristancho Ortiz, Matheus de Freitas Silva, Letizia Pruccoli, Nathália Fonseca Nadur..., Luciana Luíza de Azevedo, Arthur Eugen Kümmerle, Isabella Alvim Guedes, Laurent Emmanuel Dardenne, Luiz Felipe Leomil Coelho, Marcos J. Guimarães, Fernanda M. R. da Silva, Newton Castro, Vanessa Silva Gontijo, Viviana C. T. Rojas, Merelym Ketterym de Oliveira, Fabiana Cardoso Vilela, Alexandre Giusti-Paiva, Gisele Barbosa, Lídia Moreira Lima, Gabriela Beserra Pinheiro, Letícia Germino Veras, Márcia Renata Mortari, Andrea Tarozzi, Claudio Viegas Jr | 2022-01-01 | RSC MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Manuscript RSC TAROZZI Andrea.pdf |
| PROTAC-INDUCED GLYCOGEN SYNTHASE KINASE 3B DEGRADATION | Santini, A.; Pruccoli, L.; Guardigni, M.; De Simone, A.; Spyrakis, F.; Frabetti, F.; Andrisano, V....; Bolognesi, M. L.; Tarozzi, A.; Milelli, A. | 2022-01-01 | - | - | 4.03 Poster | - |
| Protective effects of chrysin against the neurotoxicity induced by aluminium: In vitro and in vivo studies | Campos H.M.; da Costa M.; da Silva Moreira L.K.; da Silva Neri H.F.; Branco da Silva C.R.; Prucco...li L.; dos Santos F.C.A.; Costa E.A.; Tarozzi A.; Ghedini P.C. | 2022-01-01 | TOXICOLOGY | - | 1.01 Articolo in rivista | Manuscript+Campos+et+al.+2022 only clean copy.pdf |
| Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer’s disease | Sarah Macedo Vaz, Matheus de Freitas Silva, Graziella dos Reis Rosa Franco, Marcos Jorge R. Guima...raes, Fernanda Motta R. da Silva, Newton Gonçalves Castro, Isabella Alvim Guedes, Laurent E. Dardenne, Marina Amaral Alves, Rafael Garrett da Costa, Gabriela Beserra Pinheiro, Letícia Germino Veras, Marcia Renata Mortari, Letizia Pruccoli, Andrea Tarozzi, Claudio ´ Viegas Jr. | 2022-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Accepted manuscript_TAROZZI Andrea.pdf |
| Development of new extracts of crocus sativus l. By-product from two different italian regions as new potential active ingredient in cosmetic formulations | Gigliobianco, M. R.; Cortese, M.; Peregrina, D. V.; Villa, C.; Lupidi, G.; Pruccoli, L.; Angeloni..., C.; Tarozzi, A.; Censi, R.; Di Martino, P. | 2021-01-01 | COSMETICS | - | 1.01 Articolo in rivista | Cosmetics 8-2-2021.pdf; cosmetics-08-00051-s001.zip |
| Dysregulation of long non-coding RNAs in neuroinflammation: characterization of LINC00520 and its possible role in Parkinson's disease | Fazzina, Martina; Pruccoli, Letizia; Tarozzi, Andrea; Massenzio, Francesca; Monti, Barbara; Maest...ri, Davide; Bergonzoni, Matteo; Frabetti, Flavia; Casadei, Raffaella | 2021-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Esculetin provides neuroprotection against mutant huntingtin-induced toxicity in huntington’s disease models | Pruccoli L.; Breda C.; Teti G.; Falconi M.; Giorgini F.; Tarozzi A. | 2021-01-01 | PHARMACEUTICALS | - | 1.01 Articolo in rivista | Pharmaceuticals 14 2021.pdf; pharmaceuticals-14-01044-s001.zip |