MARINELLO, JESSICA
MARINELLO, JESSICA
DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Ricercatori a tempo determinato
Anthracyclines as Topoisomerase II Poisons: From Early Studies to New Perspectives
2018-01-01 Marinello, Jessica; Delcuratolo, Maria; Capranico, Giovanni
Antisense transcripts enhanced by camptothecin at divergent CpG-island promoters associated with bursts of topoisomerase I-DNA cleavage complex and R-loop formation
2013-01-01 J. Marinello;G. Chillemi;S. Bueno;S. G. Manzo;G. Capranico
Characterization of novel antisense HIF-1α transcripts in human cancers
2011-01-01 Bertozzi Davide; Iurlaro Raffaella; Sordet Olivier; Marinello Jessica; Zaffaroni Nadia; Capranico Giovanni
Comparison of raltegravir and elvitegravir on HIV-1 integrase catalytic reactions and on a series of drug-resistant integrase mutants
2008-01-01 Marinello J; Marchand C; Mott BT; Bain A; Thomas CJ; Pommier Y
Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation.
2013-01-01 Petronzi C; Festa M; Peduto A; Castellano M; Marinello J; Massa A; Capasso A; Capranico G; La Gatta A; De Rosa M; Caraglia M; Filosa R.
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT
2009-01-01 Tumiatti V; Milelli A ; Minarini A; Micco M; Gasperi-Campani A; Roncuzzi L; Baiocchi D; Marinello J; Capranico G; Zini M; Stefanelli C; Melchiorre C
Discovery of new antisense transcripts induced by camptothecin at CpG island promoters of human cells.
2012-01-01 Marinello Jessica; Susana Bueno; Stefano G Manzo; Roberta Ragazzini; Giovanni Chillemi; Giovanni Capranico
Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: A new opportunity in the targeting of G-rich DNA structures?
2016-01-01 Amato, Jussara; Pagano, Alessia; Cosconati, Sandro; Amendola, Giorgio; Fotticchia, Iolanda; Iaccarino, Nunzia; Marinello, Jessica; De Magis, Alessio; Capranico, Giovanni; Novellino, Ettore; Pagano, Bruno; Randazzo, Antonio
Dissecting the transcriptional functions of human DNA topoisomerase I by selective inhibitors: Implications for physiological and therapeutic modulation of enzyme activity.
2010-01-01 G. Capranico; J. Marinello; L. Baranello
DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells
2019-01-01 De Magis, Alessio; Manzo, Stefano G.; Russo, Marco; Marinello, Jessica; Morigi, Rita; Sordet, Olivier; Capranico, Giovanni*
DNA Topoisomerase I differentially modulates R-loops across the human genome
2018-01-01 Manzo, Stefano G.; Hartono, Stella R.; Sanz, Lionel A.; Marinello, Jessica; De Biasi, Sara; Cossarizza, Andrea; Capranico, Giovanni*; Chedin, Frederic
Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks
2019-01-01 Cristini A.; Ricci G.; Britton S.; Salimbeni S.; Huang S.-Y.N.; Marinello J.; Calsou P.; Pommier Y.; Favre G.; Capranico G.; Gromak N.; Sordet O.
Dynamic effects of topoisomerase i inhibition on R-loops and short transcripts at active promoters
2016-01-01 Marinello, Jessica; Bertoncini, Stefania; Aloisi, Iris; Cristini, Agnese; Tagliazucchi, Guidantonio Malagoli; Forcato, Mattia; Sordet, Olivier; Capranico, Giovanni
Electron Paramagnetic Resonance (EPR) Study of Spin-Labeled Camptothecin Derivatives: A Different Look of the Ternary Complex.
2011-01-01 Ricci A; Marinello J; Bortolus M; Sanchez A; Grandas A; Pedroso E; Pommier Y; Capranico G; Maniero AL; Zagotto G.
G-quadruplex binders cause DNA damage by inducing R loops in human cancer cells.
2017-01-01 A. De Magis, S. G. Manzo, J. Marinello, R. Morigi, M. Rambaldi, O. Sodet, G. Capranico.
Genome instability by G-quadruplex ligands are mediated by R-loops in human cancer cells
2018-01-01 Alessio De Magis, Stefano G. Manzo, Jessica Marinello, Marco Russo, Olivier Sordet, Rita Morigi, Giovanni Capranico
In hepatocellular carcinoma miR-519d is up-regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2.
2012-01-01 Fornari F.; Milazzo M.; Chieco P.; Negrini M.; Marasco E.; Capranico G.; Mantovani V.; Marinello J.; Sabbioni S.; Callegari E.; Cescon M.; Ravaioli M.; Croce C.M.; Bolondi L.; Gramantieri L.
Natural product triptolide mediates cancer cell death by triggering CDK7-dependent degradation of RNA polymerase II
2012-01-01 Manzo S. G.; Z.-L. Zhou; Y.-Q. Wang; J. Marinello; J.-X. He; Y.-C. Li; J. Ding; G. Capranico; Z.-H. Miao
Novel DNA Topoisomerase IIα Inhibitors from Combined Ligand- and Structure-Based Virtual Screening
2014-01-01 Malgorzata N. Drwal;Jessica Marinello;Stefano G. Manzo;Laurence P. G. Wakelin;Giovanni Capranico;Renate Griffith
R loop-driven genome instability by G-quadruplex binders in BRCA2-silenced human cancer cells.
2018-01-01 A. De Magis, S. G. Manzo, M. Russo, J. Marinello, O. Sordet, R. Morigi, G. Capranico.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Anthracyclines as Topoisomerase II Poisons: From Early Studies to New Perspectives | Marinello, Jessica; Delcuratolo, Maria; Capranico, Giovanni | 2018-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-19-03480.pdf |
| Antisense transcripts enhanced by camptothecin at divergent CpG-island promoters associated with bursts of topoisomerase I-DNA cleavage complex and R-loop formation | J. Marinello;G. Chillemi;S. Bueno;S. G. Manzo;G. Capranico | 2013-01-01 | NUCLEIC ACIDS RESEARCH | - | 1.01 Articolo in rivista | - |
| Characterization of novel antisense HIF-1α transcripts in human cancers | Bertozzi Davide; Iurlaro Raffaella; Sordet Olivier; Marinello Jessica; Zaffaroni Nadia; Capranico... Giovanni | 2011-01-01 | CELL CYCLE | - | 1.01 Articolo in rivista | - |
| Comparison of raltegravir and elvitegravir on HIV-1 integrase catalytic reactions and on a series of drug-resistant integrase mutants | Marinello J; Marchand C; Mott BT; Bain A; Thomas CJ; Pommier Y | 2008-01-01 | BIOCHEMISTRY | - | 1.01 Articolo in rivista | - |
| Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation. | Petronzi C; Festa M; Peduto A; Castellano M; Marinello J; Massa A; Capasso A; Capranico G; La Gat...ta A; De Rosa M; Caraglia M; Filosa R. | 2013-01-01 | JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT | Tumiatti V; Milelli A ; Minarini A; Micco M; Gasperi-Campani A; Roncuzzi L; Baiocchi D; Marinello... J; Capranico G; Zini M; Stefanelli C; Melchiorre C | 2009-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Discovery of new antisense transcripts induced by camptothecin at CpG island promoters of human cells. | Marinello Jessica; Susana Bueno; Stefano G Manzo; Roberta Ragazzini; Giovanni Chillemi; Giovanni ...Capranico | 2012-01-01 | - | Insubria University Press | 4.02 Riassunto (Abstract) | - |
| Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: A new opportunity in the targeting of G-rich DNA structures? | Amato, Jussara; Pagano, Alessia; Cosconati, Sandro; Amendola, Giorgio; Fotticchia, Iolanda; Iacca...rino, Nunzia; Marinello, Jessica; De Magis, Alessio; Capranico, Giovanni; Novellino, Ettore; Pagano, Bruno; Randazzo, Antonio | 2016-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS | - | 1.01 Articolo in rivista | - |
| Dissecting the transcriptional functions of human DNA topoisomerase I by selective inhibitors: Implications for physiological and therapeutic modulation of enzyme activity. | G. Capranico; J. Marinello; L. Baranello | 2010-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER | - | 1.01 Articolo in rivista | - |
| DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells | De Magis, Alessio; Manzo, Stefano G.; Russo, Marco; Marinello, Jessica; Morigi, Rita; Sordet, Oli...vier; Capranico, Giovanni* | 2019-01-01 | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | - | 1.01 Articolo in rivista | - |
| DNA Topoisomerase I differentially modulates R-loops across the human genome | Manzo, Stefano G.; Hartono, Stella R.; Sanz, Lionel A.; Marinello, Jessica; De Biasi, Sara; Cossa...rizza, Andrea; Capranico, Giovanni*; Chedin, Frederic | 2018-01-01 | GENOME BIOLOGY | - | 1.01 Articolo in rivista | s13059-018-1478-1.pdf |
| Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks | Cristini A.; Ricci G.; Britton S.; Salimbeni S.; Huang S.-Y.N.; Marinello J.; Calsou P.; Pommier ...Y.; Favre G.; Capranico G.; Gromak N.; Sordet O. | 2019-01-01 | CELL REPORTS | - | 1.01 Articolo in rivista | 1-s2.0-S2211124719310812-main.pdf |
| Dynamic effects of topoisomerase i inhibition on R-loops and short transcripts at active promoters | Marinello, Jessica; Bertoncini, Stefania; Aloisi, Iris; Cristini, Agnese; Tagliazucchi, Guidanton...io Malagoli; Forcato, Mattia; Sordet, Olivier; Capranico, Giovanni | 2016-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | - |
| Electron Paramagnetic Resonance (EPR) Study of Spin-Labeled Camptothecin Derivatives: A Different Look of the Ternary Complex. | Ricci A; Marinello J; Bortolus M; Sanchez A; Grandas A; Pedroso E; Pommier Y; Capranico G; Manier...o AL; Zagotto G. | 2011-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| G-quadruplex binders cause DNA damage by inducing R loops in human cancer cells. | A. De Magis, S. G. Manzo, J. Marinello, R. Morigi, M. Rambaldi, O. Sodet, G. Capranico. | 2017-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Genome instability by G-quadruplex ligands are mediated by R-loops in human cancer cells |
Alessio De Magis, Stefano G. Manzo, Jessica Marinello, Marco Russo, Olivier Sordet, Rita Morigi,... Giovanni Capranico |
2018-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| In hepatocellular carcinoma miR-519d is up-regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2. | Fornari F.; Milazzo M.; Chieco P.; Negrini M.; Marasco E.; Capranico G.; Mantovani V.; Marinello ...J.; Sabbioni S.; Callegari E.; Cescon M.; Ravaioli M.; Croce C.M.; Bolondi L.; Gramantieri L. | 2012-01-01 | JOURNAL OF PATHOLOGY | - | 1.01 Articolo in rivista | - |
| Natural product triptolide mediates cancer cell death by triggering CDK7-dependent degradation of RNA polymerase II | Manzo S. G.; Z.-L. Zhou; Y.-Q. Wang; J. Marinello; J.-X. He; Y.-C. Li; J. Ding; G. Capranico; Z.-...H. Miao | 2012-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| Novel DNA Topoisomerase IIα Inhibitors from Combined Ligand- and Structure-Based Virtual Screening | Malgorzata N. Drwal;Jessica Marinello;Stefano G. Manzo;Laurence P. G. Wakelin;Giovanni Capranico;...Renate Griffith | 2014-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | - |
| R loop-driven genome instability by G-quadruplex binders in BRCA2-silenced human cancer cells. | A. De Magis, S. G. Manzo, M. Russo, J. Marinello, O. Sordet, R. Morigi, G. Capranico. | 2018-01-01 | CANCER RESEARCH | - | 4.03 Poster | - |