MARINELLO, JESSICA
MARINELLO, JESSICA
DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Docenti di ruolo di IIa fascia
Human DNA topoisomerase I poisoning causes R loop-mediated genome instability attenuated by transcription factor IIS
2024 Renée Concetta Duardo , Jessica Marinello , Marco Russo , Sara Morelli , Simona Pepe , Federico Guerra , Belén Gómez-González , Andrés Aguilera , Giovanni Capranico
Immunofluorescence microscopy of G-quadruplexes and R-loops
2024 Miglietta, Giulia; Marinello, Jessica; Capranico, Giovanni
TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks
2024 Geraud M.; Cristini A.; Salimbeni S.; Bery N.; Jouffret V.; Russo M.; Ajello A.C.; Fernandez Martinez L.; Marinello J.; Cordelier P.; Trouche D.; Favre G.; Nicolas E.; Capranico G.; Sordet O.
Balancing Affinity, Selectivity, and Cytotoxicity of Hydrazone-Based G-Quadruplex Ligands for Activation of Interferon β Genes in Cancer Cells
2022 Marzano S.; Miglietta G.; Morigi R.; Marinello J.; Arleo A.; Procacci M.; Locatelli A.; Leoni A.; Pagano B.; Randazzo A.; Amato J.; Capranico G.
Highly Purified Top1-Bound DNA Fragments
2022 Jessica Marinello, Giovanni Capranico
Ligands stimulating antitumour immunity as the next G-quadruplex challenge
2022 Miglietta G.; Marinello J.; Russo M.; Capranico G.
Topoisomerase I poison-triggered immune gene activation is markedly reduced in human small-cell lung cancers by impairment of the cGAS/STING pathway
2022 Jessica Marinello, Andrea Arleo, Marco Russo, Maria Delcuratolo, Francesca Ciccarelli, Yves Pommier, Giovanni Capranico.
DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells
2019 De Magis, Alessio; Manzo, Stefano G.; Russo, Marco; Marinello, Jessica; Morigi, Rita; Sordet, Olivier; Capranico, Giovanni*
Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks
2019 Cristini A.; Ricci G.; Britton S.; Salimbeni S.; Huang S.-Y.N.; Marinello J.; Calsou P.; Pommier Y.; Favre G.; Capranico G.; Gromak N.; Sordet O.
Anthracyclines as Topoisomerase II Poisons: From Early Studies to New Perspectives
2018 Marinello, Jessica; Delcuratolo, Maria; Capranico, Giovanni
DNA Topoisomerase I differentially modulates R-loops across the human genome
2018 Manzo, Stefano G.; Hartono, Stella R.; Sanz, Lionel A.; Marinello, Jessica; De Biasi, Sara; Cossarizza, Andrea; Capranico, Giovanni*; Chedin, Frederic
Genome instability by G-quadruplex ligands are mediated by R-loops in human cancer cells
2018 Alessio De Magis, Stefano G. Manzo, Jessica Marinello, Marco Russo, Olivier Sordet, Rita Morigi, Giovanni Capranico
R loop-driven genome instability by G-quadruplex binders in BRCA2-silenced human cancer cells.
2018 A. De Magis, S. G. Manzo, M. Russo, J. Marinello, O. Sordet, R. Morigi, G. Capranico.
Targeting human telomeric and promoter G-quardruplexes: synthesis, biophysical and biological studies of new guanylhydrazones as potential antitumor agents
2018 R. Morigi, J. Amato, N. Iaccarino, B. Pagano, A. Locatelli, A. Leoni, M. Rambaldi, G. Miglietta, J. Marinello, G. Capranico, E. Novellino, A. Randazzo
G-quadruplex binders cause DNA damage by inducing R loops in human cancer cells.
2017 A. De Magis, S. G. Manzo, J. Marinello, R. Morigi, M. Rambaldi, O. Sodet, G. Capranico.
RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation
2017 Miglietta, Giulia; Cogoi, Susanna; Marinello, Jessica; Capranico, Giovanni; Tikhomirov, Alexander S.; Shchekotikhin, Andrey; Xodo, Luigi E.*
Type I DNA Topoisomerases
2017 Capranico, Giovanni; Marinello, Jessica; Chillemi, Giovanni
Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: A new opportunity in the targeting of G-rich DNA structures?
2016 Amato, Jussara; Pagano, Alessia; Cosconati, Sandro; Amendola, Giorgio; Fotticchia, Iolanda; Iaccarino, Nunzia; Marinello, Jessica; De Magis, Alessio; Capranico, Giovanni; Novellino, Ettore; Pagano, Bruno; Randazzo, Antonio
Dynamic effects of topoisomerase i inhibition on R-loops and short transcripts at active promoters
2016 Marinello, Jessica; Bertoncini, Stefania; Aloisi, Iris; Cristini, Agnese; Tagliazucchi, Guidantonio Malagoli; Forcato, Mattia; Sordet, Olivier; Capranico, Giovanni
Novel DNA Topoisomerase IIα Inhibitors from Combined Ligand- and Structure-Based Virtual Screening
2014 Malgorzata N. Drwal;Jessica Marinello;Stefano G. Manzo;Laurence P. G. Wakelin;Giovanni Capranico;Renate Griffith
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Human DNA topoisomerase I poisoning causes R loop-mediated genome instability attenuated by transcription factor IIS | Renée Concetta Duardo , Jessica Marinello , Marco Russo , Sara Morelli , Simona Pepe , Federico G...uerra , Belén Gómez-González , Andrés Aguilera , Giovanni Capranico | 2024-01-01 | SCIENCE ADVANCES | - | 1.01 Articolo in rivista | - |
| Immunofluorescence microscopy of G-quadruplexes and R-loops | Miglietta, Giulia; Marinello, Jessica; Capranico, Giovanni | 2024-01-01 | - | Academic Press | 2.01 Capitolo / saggio in libro | - |
| TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks | Geraud M.; Cristini A.; Salimbeni S.; Bery N.; Jouffret V.; Russo M.; Ajello A.C.; Fernandez Mart...inez L.; Marinello J.; Cordelier P.; Trouche D.; Favre G.; Nicolas E.; Capranico G.; Sordet O. | 2024-01-01 | CELL REPORTS | - | 1.01 Articolo in rivista | - |
| Balancing Affinity, Selectivity, and Cytotoxicity of Hydrazone-Based G-Quadruplex Ligands for Activation of Interferon β Genes in Cancer Cells | Marzano S.; Miglietta G.; Morigi R.; Marinello J.; Arleo A.; Procacci M.; Locatelli A.; Leoni A.;... Pagano B.; Randazzo A.; Amato J.; Capranico G. | 2022-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | JMC.pdf; jm2c00772_si_002.pdf |
| Highly Purified Top1-Bound DNA Fragments | Jessica Marinello, Giovanni Capranico | 2022-01-01 | - | Humana Press Inc. | 2.01 Capitolo / saggio in libro | - |
| Ligands stimulating antitumour immunity as the next G-quadruplex challenge | Miglietta G.; Marinello J.; Russo M.; Capranico G. | 2022-01-01 | MOLECULAR CANCER | - | 1.01 Articolo in rivista | Mol canc.pdf |
| Topoisomerase I poison-triggered immune gene activation is markedly reduced in human small-cell lung cancers by impairment of the cGAS/STING pathway | Jessica Marinello, Andrea Arleo, Marco Russo, Maria Delcuratolo, Francesca Ciccarelli, Yves Pomm...ier, Giovanni Capranico. | 2022-01-01 | BRITISH JOURNAL OF CANCER | - | 1.01 Articolo in rivista | BJC.pdf |
| DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells | De Magis, Alessio; Manzo, Stefano G.; Russo, Marco; Marinello, Jessica; Morigi, Rita; Sordet, Oli...vier; Capranico, Giovanni* | 2019-01-01 | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | - | 1.01 Articolo in rivista | - |
| Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks | Cristini A.; Ricci G.; Britton S.; Salimbeni S.; Huang S.-Y.N.; Marinello J.; Calsou P.; Pommier ...Y.; Favre G.; Capranico G.; Gromak N.; Sordet O. | 2019-01-01 | CELL REPORTS | - | 1.01 Articolo in rivista | 1-s2.0-S2211124719310812-main.pdf |
| Anthracyclines as Topoisomerase II Poisons: From Early Studies to New Perspectives | Marinello, Jessica; Delcuratolo, Maria; Capranico, Giovanni | 2018-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-19-03480.pdf |
| DNA Topoisomerase I differentially modulates R-loops across the human genome | Manzo, Stefano G.; Hartono, Stella R.; Sanz, Lionel A.; Marinello, Jessica; De Biasi, Sara; Cossa...rizza, Andrea; Capranico, Giovanni*; Chedin, Frederic | 2018-01-01 | GENOME BIOLOGY | - | 1.01 Articolo in rivista | s13059-018-1478-1.pdf |
| Genome instability by G-quadruplex ligands are mediated by R-loops in human cancer cells |
Alessio De Magis, Stefano G. Manzo, Jessica Marinello, Marco Russo, Olivier Sordet, Rita Morigi,... Giovanni Capranico |
2018-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| R loop-driven genome instability by G-quadruplex binders in BRCA2-silenced human cancer cells. | A. De Magis, S. G. Manzo, M. Russo, J. Marinello, O. Sordet, R. Morigi, G. Capranico. | 2018-01-01 | CANCER RESEARCH | - | 4.03 Poster | - |
| Targeting human telomeric and promoter G-quardruplexes: synthesis, biophysical and biological studies of new guanylhydrazones as potential antitumor agents | R. Morigi, J. Amato, N. Iaccarino, B. Pagano, A. Locatelli, A. Leoni, M. Rambaldi, G. Miglietta, ...J. Marinello, G. Capranico, E. Novellino, A. Randazzo | 2018-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| G-quadruplex binders cause DNA damage by inducing R loops in human cancer cells. | A. De Magis, S. G. Manzo, J. Marinello, R. Morigi, M. Rambaldi, O. Sodet, G. Capranico. | 2017-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation | Miglietta, Giulia; Cogoi, Susanna; Marinello, Jessica; Capranico, Giovanni; Tikhomirov, Alexander... S.; Shchekotikhin, Andrey; Xodo, Luigi E.* | 2017-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Type I DNA Topoisomerases | Capranico, Giovanni; Marinello, Jessica; Chillemi, Giovanni | 2017-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: A new opportunity in the targeting of G-rich DNA structures? | Amato, Jussara; Pagano, Alessia; Cosconati, Sandro; Amendola, Giorgio; Fotticchia, Iolanda; Iacca...rino, Nunzia; Marinello, Jessica; De Magis, Alessio; Capranico, Giovanni; Novellino, Ettore; Pagano, Bruno; Randazzo, Antonio | 2016-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS | - | 1.01 Articolo in rivista | - |
| Dynamic effects of topoisomerase i inhibition on R-loops and short transcripts at active promoters | Marinello, Jessica; Bertoncini, Stefania; Aloisi, Iris; Cristini, Agnese; Tagliazucchi, Guidanton...io Malagoli; Forcato, Mattia; Sordet, Olivier; Capranico, Giovanni | 2016-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | - |
| Novel DNA Topoisomerase IIα Inhibitors from Combined Ligand- and Structure-Based Virtual Screening | Malgorzata N. Drwal;Jessica Marinello;Stefano G. Manzo;Laurence P. G. Wakelin;Giovanni Capranico;...Renate Griffith | 2014-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | - |