MANCINI, MANUELA
MANCINI, MANUELA
DIPARTIMENTO DI MEDICINA SPECIALISTICA, DIAGNOSTICA E SPERIMENTALE (attivo dal 28/10/2011 al 31/12/2022)
Assegnisti
M. Mancini; Manuela Mancini; Mancini M; Mancini
Prognosis in Chronic Myeloid Leukemia: Baseline Factors, Dynamic Risk Assessment and Novel Insights
2023 Iezza M.; Cortesi S.; Ottaviani E.; Mancini M.; Venturi C.; Monaldi C.; De Santis S.; Testoni N.; Soverini S.; Rosti G.; Cavo M.; Castagnetti F.
SETD2 non genomic loss of function in advanced systemic mastocytosis is mediated by an Aurora kinase A/MDM2 axis and can be therapeutically targeted
2023 Mancini M.; Monaldi C.; De Santis S.; Papayannidis C.; Rondoni M.; Sartor C.; Bruno S.; Pagano L.; Criscuolo M.; Zanotti R.; Bonifacio M.; Tosi P.; Arock M.; Valent P.; Cavo M.; Soverini S.
CML-184 A Novel Droplet Digital PCR Strategy for Rapid and Sensitive Detection of BCR::ABL1 Kinase Domain Mutations Conferring Resistance to Second-Generation Tyrosine Kinase Inhibitors
2022 de Santis S.; Monaldi C.; Martelli M.; Mancini M.; Bruno S.; Castagnetti F.; Gugliotta G.; Polakova K.M.; Ernst T.; Maar D.; Corner A.; Cavo M.; Soverini S.
Combined Inhibition of Polo-like Kinase-1 and Wee1 as a New Therapeutic Strategy to Induce Apoptotic Cell Death in Neoplastic Mast Cells
2022 Mancini M.; Monaldi C.; De Santis S.; Rondoni M.; Papayannidis C.; Sartor C.; Curti A.; Bruno S.; Cavo M.; Soverini S.
Droplet digital PCR for the detection of second-generation tyrosine kinase inhibitor-resistant BCR::ABL1 kinase domain mutations in chronic myeloid leukemia
2022 Soverini, S.; De Santis, S.; Martelli, M.; Monaldi, C.; Castagnetti, F.; Gugliotta, G.; Papayannidis, C.; Mancini, M.; Bruno, S.; Venturi, C.; Machova Polakova, K.; Ernst, T.; Maar, D.; Corner, A.; Cavo, M.
MPN-182 Droplet Digital PCR for Non-Invasive Detection of the KIT D816V Mutation in the Peripheral Blood of Patients With Suspected Systemic Mastocytosis
2022 Monaldi C.; de Santis S.; Mancini M.; Papayannidis C.; Sartor C.; Rondoni M.; Bruno S.; Cavo M.; Soverini S.
Overcoming Resistance to Kinase Inhibitors: The Paradigm of Chronic Myeloid Leukemia
2022 De Santis, S.; Monaldi, C.; Mancini, M.; Bruno, S.; Cavo, M.; Soverini, S.
Polo-like kinase-1, Aurora kinase A and WEE1 kinase are promising druggable targets in CML cells displaying BCR::ABL1-independent resistance to tyrosine kinase inhibitors
2022 Mancini M.; De Santis S.; Monaldi C.; Castagnetti F.; Lonetti A.; Bruno S.; Dan E.; Sinigaglia B.; Rosti G.; Cavo M.; Gugliotta G.; Soverini S.
Case Report: A Novel Activating FLT3 Mutation in Acute Myeloid Leukemia
2021 Bruno S.; Bandini L.; Patuelli A.; Robustelli V.; Venturi C.; Mancini M.; Forte D.; De Santis S.; Monaldi C.; Grassi A.; Chiurumbolo G.; Paolini S.; Cristiano G.; Papayannidis C.; Sartor C.; Nanni J.; Ottaviani E.; Curti A.; Cavo M.; Soverini S.
Systemic mastocytosis: Molecular landscape and implications for treatment
2021 Monaldi C.; de Santis S.; Mancini M.; Bruno S.; Cavo M.; Soverini S.
Targeting leukemic stem cells in chronic myeloid leukemia: Is it worth the effort?
2021 Soverini S.; De Santis S.; Monaldi C.; Bruno S.; Mancini M.
The role of hypoxic bone marrow microenvironment in acute myeloid leukemia and future therapeutic opportunities
2021 Bruno S.; Mancini M.; De Santis S.; Monaldi C.; Cavo M.; Soverini S.
Ponatinib treatment in chronic myeloid leukemia cell lines targets aurora kinase A/FOXM1 axis
2020 Mancini, Manuela; De Santis, Sara; Monaldi, Cecilia; Bavaro, Luana; Martelli, Margherita; Gugliotta, Gabriele; Castagnetti, Fausto; Rosti, Gianantonio; Santucci, Maria Alessandra; Martinelli, Giovanni; Cavo, Michele; Soverini, Simona
Recent advances in the molecular biology of systemic mastocytosis: Implications for diagnosis, prognosis, and therapy
2020 Martelli M.; Monaldi C.; De Santis S.; Bruno S.; Mancini M.; Cavo M.; Soverini S.
Hyper-activation of Aurora kinase a-polo-like kinase 1-FOXM1 axis promotes chronic myeloid leukemia resistance to tyrosine kinase inhibitors
2019 Mancini M.; De Santis S.; Monaldi C.; Bavaro L.; Martelli M.; Castagnetti F.; Gugliotta G.; Rosti G.; Santucci M.A.; Martinelli G.; Cavo M.; Soverini S.
Chronic myeloid leukemia: the paradigm of targeting oncogenic tyrosine kinase signaling and counteracting resistance for successful cancer therapy
2018 Soverini, Simona; Mancini, Manuela; Bavaro, Luana; Cavo, Michele; Martinelli, Giovanni
SETD2 and histone H3 lysine 36 methylation deficiency in advanced systemic mastocytosis
2018 Martinelli, G; Mancini, M; De Benedittis, C; Rondoni, M; Papayannidis, C; Manfrini, M; Meggendorfer, M; Calogero, R; Guadagnuolo, V; Fontana, M. C; Bavaro, L; Padella, A; Zago, E; Pagano, L; Zanotti, R; Scaffidi, L; Specchia, G; Albano, F; Merante, S; Elena, C; Savini, P; Gangemi, D; Tosi, P; Ciceri, F; Poletti, G; Riccioni, L; Morigi, F; Delledonne, M; Haferlach, T; Cavo, M; Valent, P; Soverini, S.
Chibby 1: A new component of β-catenin-signaling in chronic myeloid leukemia
2017 Mancini, Manuela; Soverini, Simona; Gugliotta, Gabriele; Santucci, MARIA ALESSANDRA; Rosti, Gianantonio; Cavo, Michele; Martinelli, Giovanni; Castagnetti, Fausto
FOXM1 Transcription Factor: A New Component of Chronic Myeloid Leukemia Stem Cell Proliferation Advantage
2017 Mancini, Manuela; Castagnetti, Fausto; Soverini, Simona; Leo, Elisa; De Benedittis, Caterina; Gugliotta, Gabriele; Rosti, Gianantonio; Bavaro, Luana; De Santis, Sara; Monaldi, Cecilia; Martelli, Margherita; Santucci, Maria Alessandra; Cavo, Michele; Martinelli, Giovanni
Polo-like Kinase-1 and Aurora Kinase A As Novel Therapeutic Targets in Neoplastic Mast Cells
2017 Manuela Mancini, Cecilia Monaldi, Sara De Santis, Cristina Papayannidis, Michela Rondoni, Maria Chiara Abbenante, Luana Bavaro, Margherita Martelli, Roberta Zanotti, Livio Pagano, Michele Cavo, Peter Valent, Giovanni Martinelli, Simona Soverini
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Prognosis in Chronic Myeloid Leukemia: Baseline Factors, Dynamic Risk Assessment and Novel Insights | Iezza M.; Cortesi S.; Ottaviani E.; Mancini M.; Venturi C.; Monaldi C.; De Santis S.; Testoni N.;... Soverini S.; Rosti G.; Cavo M.; Castagnetti F. | 2023-01-01 | CELLS | - | 1.01 Articolo in rivista | cells-12-01703-v2.pdf |
| SETD2 non genomic loss of function in advanced systemic mastocytosis is mediated by an Aurora kinase A/MDM2 axis and can be therapeutically targeted | Mancini M.; Monaldi C.; De Santis S.; Papayannidis C.; Rondoni M.; Sartor C.; Bruno S.; Pagano L....; Criscuolo M.; Zanotti R.; Bonifacio M.; Tosi P.; Arock M.; Valent P.; Cavo M.; Soverini S. | 2023-01-01 | BIOMARKER RESEARCH | - | 1.01 Articolo in rivista | Mancini_2023.pdf; 40364_2023_468_MOESM1_ESM.docx |
| CML-184 A Novel Droplet Digital PCR Strategy for Rapid and Sensitive Detection of BCR::ABL1 Kinase Domain Mutations Conferring Resistance to Second-Generation Tyrosine Kinase Inhibitors | de Santis S.; Monaldi C.; Martelli M.; Mancini M.; Bruno S.; Castagnetti F.; Gugliotta G.; Polako...va K.M.; Ernst T.; Maar D.; Corner A.; Cavo M.; Soverini S. | 2022-01-01 | CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | - | 1.01 Articolo in rivista | - |
| Combined Inhibition of Polo-like Kinase-1 and Wee1 as a New Therapeutic Strategy to Induce Apoptotic Cell Death in Neoplastic Mast Cells | Mancini M.; Monaldi C.; De Santis S.; Rondoni M.; Papayannidis C.; Sartor C.; Curti A.; Bruno S.;... Cavo M.; Soverini S. | 2022-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-14-00738.pdf; cancers-14-00738-s001.zip |
| Droplet digital PCR for the detection of second-generation tyrosine kinase inhibitor-resistant BCR::ABL1 kinase domain mutations in chronic myeloid leukemia | Soverini, S.; De Santis, S.; Martelli, M.; Monaldi, C.; Castagnetti, F.; Gugliotta, G.; Papayanni...dis, C.; Mancini, M.; Bruno, S.; Venturi, C.; Machova Polakova, K.; Ernst, T.; Maar, D.; Corner, A.; Cavo, M. | 2022-01-01 | LEUKEMIA | - | 1.01 Articolo in rivista | - |
| MPN-182 Droplet Digital PCR for Non-Invasive Detection of the KIT D816V Mutation in the Peripheral Blood of Patients With Suspected Systemic Mastocytosis | Monaldi C.; de Santis S.; Mancini M.; Papayannidis C.; Sartor C.; Rondoni M.; Bruno S.; Cavo M.; ...Soverini S. | 2022-01-01 | CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | - | 1.01 Articolo in rivista | - |
| Overcoming Resistance to Kinase Inhibitors: The Paradigm of Chronic Myeloid Leukemia | De Santis, S.; Monaldi, C.; Mancini, M.; Bruno, S.; Cavo, M.; Soverini, S. | 2022-01-01 | ONCOTARGETS AND THERAPY | - | 1.01 Articolo in rivista | OTT-289306-overcoming-resistance-to-kinase-inhibitors--the-paradigm-of-.pdf |
| Polo-like kinase-1, Aurora kinase A and WEE1 kinase are promising druggable targets in CML cells displaying BCR::ABL1-independent resistance to tyrosine kinase inhibitors | Mancini M.; De Santis S.; Monaldi C.; Castagnetti F.; Lonetti A.; Bruno S.; Dan E.; Sinigaglia B....; Rosti G.; Cavo M.; Gugliotta G.; Soverini S. | 2022-01-01 | FRONTIERS IN ONCOLOGY | - | 1.01 Articolo in rivista | fonc-12-901132.pdf; file supplementari.zip |
| Case Report: A Novel Activating FLT3 Mutation in Acute Myeloid Leukemia | Bruno S.; Bandini L.; Patuelli A.; Robustelli V.; Venturi C.; Mancini M.; Forte D.; De Santis S.;... Monaldi C.; Grassi A.; Chiurumbolo G.; Paolini S.; Cristiano G.; Papayannidis C.; Sartor C.; Nanni J.; Ottaviani E.; Curti A.; Cavo M.; Soverini S. | 2021-01-01 | FRONTIERS IN ONCOLOGY | - | 1.01 Articolo in rivista | fonc-11-728613.pdf |
| Systemic mastocytosis: Molecular landscape and implications for treatment | Monaldi C.; de Santis S.; Mancini M.; Bruno S.; Cavo M.; Soverini S. | 2021-01-01 | MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES | - | 1.01 Articolo in rivista | mjhid-13-1-e2021046.pdf |
| Targeting leukemic stem cells in chronic myeloid leukemia: Is it worth the effort? | Soverini S.; De Santis S.; Monaldi C.; Bruno S.; Mancini M. | 2021-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-22-07093-v2.pdf |
| The role of hypoxic bone marrow microenvironment in acute myeloid leukemia and future therapeutic opportunities | Bruno S.; Mancini M.; De Santis S.; Monaldi C.; Cavo M.; Soverini S. | 2021-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-22-06857-v2.pdf |
| Ponatinib treatment in chronic myeloid leukemia cell lines targets aurora kinase A/FOXM1 axis | Mancini, Manuela; De Santis, Sara; Monaldi, Cecilia; Bavaro, Luana; Martelli, Margherita; Gugliot...ta, Gabriele; Castagnetti, Fausto; Rosti, Gianantonio; Santucci, Maria Alessandra; Martinelli, Giovanni; Cavo, Michele; Soverini, Simona | 2020-01-01 | HEMATOLOGICAL ONCOLOGY | - | 1.01 Articolo in rivista | - |
| Recent advances in the molecular biology of systemic mastocytosis: Implications for diagnosis, prognosis, and therapy | Martelli M.; Monaldi C.; De Santis S.; Bruno S.; Mancini M.; Cavo M.; Soverini S. | 2020-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | Martelli_ijms_2020.pdf |
| Hyper-activation of Aurora kinase a-polo-like kinase 1-FOXM1 axis promotes chronic myeloid leukemia resistance to tyrosine kinase inhibitors | Mancini M.; De Santis S.; Monaldi C.; Bavaro L.; Martelli M.; Castagnetti F.; Gugliotta G.; Rosti... G.; Santucci M.A.; Martinelli G.; Cavo M.; Soverini S. | 2019-01-01 | JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH | - | 1.01 Articolo in rivista | Mancini_J Exp Clin Cancer Res_2019.pdf |
| Chronic myeloid leukemia: the paradigm of targeting oncogenic tyrosine kinase signaling and counteracting resistance for successful cancer therapy | Soverini, Simona; Mancini, Manuela; Bavaro, Luana; Cavo, Michele; Martinelli, Giovanni | 2018-01-01 | MOLECULAR CANCER | - | 1.01 Articolo in rivista | document.pdf |
| SETD2 and histone H3 lysine 36 methylation deficiency in advanced systemic mastocytosis | Martinelli, G; Mancini, M; De Benedittis, C; Rondoni, M; Papayannidis, C; Manfrini, M; Meggendorf...er, M; Calogero, R; Guadagnuolo, V; Fontana, M. C; Bavaro, L; Padella, A; Zago, E; Pagano, L; Zanotti, R; Scaffidi, L; Specchia, G; Albano, F; Merante, S; Elena, C; Savini, P; Gangemi, D; Tosi, P; Ciceri, F; Poletti, G; Riccioni, L; Morigi, F; Delledonne, M; Haferlach, T; Cavo, M; Valent, P; Soverini, S. | 2018-01-01 | LEUKEMIA | - | 1.01 Articolo in rivista | leu2017183.pdf; leu2017183x1.docx |
| Chibby 1: A new component of β-catenin-signaling in chronic myeloid leukemia | Mancini, Manuela; Soverini, Simona; Gugliotta, Gabriele; Santucci, MARIA ALESSANDRA; Rosti, Giana...ntonio; Cavo, Michele; Martinelli, Giovanni; Castagnetti, Fausto | 2017-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
| FOXM1 Transcription Factor: A New Component of Chronic Myeloid Leukemia Stem Cell Proliferation Advantage | Mancini, Manuela; Castagnetti, Fausto; Soverini, Simona; Leo, Elisa; De Benedittis, Caterina; Gug...liotta, Gabriele; Rosti, Gianantonio; Bavaro, Luana; De Santis, Sara; Monaldi, Cecilia; Martelli, Margherita; Santucci, Maria Alessandra; Cavo, Michele; Martinelli, Giovanni | 2017-01-01 | JOURNAL OF CELLULAR BIOCHEMISTRY | - | 1.01 Articolo in rivista | - |
| Polo-like Kinase-1 and Aurora Kinase A As Novel Therapeutic Targets in Neoplastic Mast Cells | Manuela Mancini, Cecilia Monaldi, Sara De Santis, Cristina Papayannidis, Michela Rondoni, Maria C...hiara Abbenante, Luana Bavaro, Margherita Martelli, Roberta Zanotti, Livio Pagano, Michele Cavo, Peter Valent, Giovanni Martinelli, Simona Soverini | 2017-01-01 | BLOOD | - | 1.06 Abstract in rivista | - |