BASAGNI, FILIPPO
BASAGNI, FILIPPO
DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Ricercatori a tempo determinato
Double Attack to Oxidative Stress in Neurodegenerative Disorders: MAO-B and Nrf2 as Elected Targets
2023 Basagni, Filippo; Di Paolo, Maria Luisa; Cozza, Giorgio; Dalla Via, Lisa; Fagiani, Francesca; Lanni, Cristina; Rosini, Michela; Minarini, Anna
From Monoamine Oxidase Inhibition to Antiproliferative Activity: New Biological Perspectives for Polyamine Analogs
2023 Nordio G.; Piazzola F.; Cozza G.; Rossetto M.; Cervelli M.; Minarini A.; Basagni F.; Tassinari E.; Dalla Via L.; Milelli A.; Di Paolo M.L.
Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties
2023 Basagni, Filippo; Ortega, Jose A; Bertozzi, Sine M; Armirotti, Andrea; Summa, Maria; Bertorelli, Rosalia; Bartolini, Manuela; Mellor, Ian R; Bedeschi, Martina; Bottegoni, Giovanni; Lembo, Vittorio; Minarini, Anna; Cavalli, Andrea; Rosini, Michela
Polyamine–Drug Conjugates: Do They Boost Drug Activity?
2023 Basagni F.; Marotta G.; Rosini M.; Minarini A.
Radiosynthesis, Preclinical, and Clinical Positron Emission Tomography Studies of Carbon-11 Labeled Endogenous and Natural Exogenous Compounds
2023 Antonio Shegani, Steven Kealey, Federico Luzi, Filippo Basagni, Joana do Mar Machado, Sevban Doğan Ekici, Alessandra Ferocino, Antony D. Gee,* Salvatore Bongarzone*
Inhibition of β-Amyloid Aggregation in Alzheimer's Disease: The Key Role of (Pro)electrophilic Warheads
2022 Basagni, Filippo; Naldi, Marina; Ginex, Tiziana; Luque, F Javier; Fagiani, Francesca; Lanni, Cristina; Iurlo, Matteo; Marcaccio, Massimo; Minarini, Anna; Bartolini, Manuela; Rosini, Michela
Nature-Inspired Hybrids (NIH) Improve Proteostasis by Activating Nrf2-Mediated Protective Pathways in Retinal Pigment Epithelial Cells
2022 Koskela, Ali; Manai, Federico; Basagni, Filippo; Liukkonen, Mikko; Rosini, Michela; Govoni, Stefano; Monte, Massimo Dal; Smedowski, Adrian; Kaarniranta, Kai; Amadio, Marialaura
Role of Fyn Kinase Inhibitors in Switching Neuroinflammatory Pathways
2022 Marotta, Giambattista; Basagni, Filippo; Rosini, Michela; Minarini, Anna
A nature‐inspired nrf2 activator protects retinal explants from oxidative stress and neurodegeneration
2021 Rossino M.G.; Amato R.; Amadio M.; Rosini M.; Basagni F.; Cammalleri M.; Dal Monte M.; Casini G.
Eye-Light on Age-Related Macular Degeneration: Targeting Nrf2-Pathway as a Novel Therapeutic Strategy for Retinal Pigment Epithelium
2020 Catanzaro M.; Lanni C.; Basagni F.; Rosini M.; Govoni S.; Amadio M.
Functionalized Cannabinoid Subtype 2 Receptor Ligands: Fluorescent, PET, Photochromic and Covalent Molecular Probes
2020 Basagni F.; Rosini M.; Decker M.
Memantine Derivatives as Multitarget Agents in Alzheimer’s Disease
2020 Marotta G.; Basagni F.; Rosini M.; Minarini A.
NRF2 and PPAR-γ Pathways in Oligodendrocyte Progenitors: Focus on Ros Protection, Mitochondrial Biogenesis and Promotion of Cell Differentiation
2020 De Nuccio C.; Bernardo A.; Troiano C.; Brignone M.S.; Falchi M.; Greco A.; Rosini M.; Basagni F.; Lanni C.; Serafini M.M.; Minghetti L.; Visentin S.
Targeting Cytokine Release Through the Differential Modulation of Nrf2 and NF-κB Pathways by Electrophilic/Non-Electrophilic Compounds
2020 Fagiani F.; Catanzaro M.; Buoso E.; Basagni F.; Di Marino D.; Raniolo S.; Amadio M.; Frost E.H.; Corsini E.; Racchi M.; Fulop T.; Govoni S.; Rosini M.; Lanni C.
Development of [18F]FAMTO: A novel fluorine-18 labelled positron emission tomography (PET) radiotracer for imaging CYP11B1 and CYP11B2 enzymes in adrenal glands
2019 Bongarzone, Salvatore; Basagni, Filippo; Sementa, Teresa; Singh, Nisha; Gakpetor, Caleb; Faugeras, Vincent; Bordoloi, Jayanta; Gee, Antony D.*
Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase
2019 Di Paolo, Maria Luisa; Cervelli, Manuela; Mariottini, Paolo; Leonetti, Alessia; Polticelli, Fabio; Rosini, Michela; Milelli, Andrea; Basagni, Filippo; Venerando, Rina; Agostinelli, Enzo; Minarini, Anna
Lights and shadows of electrophile signaling: Focus on the Nrf2-Keap1 pathway
2019 Basagni F.; Lanni C.; Minarini A.; Rosini M.
Merging memantine and ferulic acid to probe connections between NMDA receptors, oxidative stress and amyloid-β peptide in Alzheimer's disease
2019 Rosini M.; Simoni E.; Caporaso R.; Basagni F.; Catanzaro M.; Abu I.F.; Fagiani F.; Fusco F.; Masuzzo S.; Albani D.; Lanni C.; Mellor I.R.; Minarini A.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Double Attack to Oxidative Stress in Neurodegenerative Disorders: MAO-B and Nrf2 as Elected Targets | Basagni, Filippo; Di Paolo, Maria Luisa; Cozza, Giorgio; Dalla Via, Lisa; Fagiani, Francesca; Lan...ni, Cristina; Rosini, Michela; Minarini, Anna | 2023-01-01 | MOLECULES | - | 1.01 Articolo in rivista | molecules-28-07424.pdf; molecules-2640884-supplementary.pdf |
| From Monoamine Oxidase Inhibition to Antiproliferative Activity: New Biological Perspectives for Polyamine Analogs | Nordio G.; Piazzola F.; Cozza G.; Rossetto M.; Cervelli M.; Minarini A.; Basagni F.; Tassinari E....; Dalla Via L.; Milelli A.; Di Paolo M.L. | 2023-01-01 | MOLECULES | - | 1.01 Articolo in rivista | molecules-28-06329-v3.pdf; molecules-2562834-supplementary.pdf |
| Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties | Basagni, Filippo; Ortega, Jose A; Bertozzi, Sine M; Armirotti, Andrea; Summa, Maria; Bertorelli, ...Rosalia; Bartolini, Manuela; Mellor, Ian R; Bedeschi, Martina; Bottegoni, Giovanni; Lembo, Vittorio; Minarini, Anna; Cavalli, Andrea; Rosini, Michela | 2023-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Eur. J. Med.Chem. 2023.pdf; 1-s2.0-S0223523423007705-mmc1.docx |
| Polyamine–Drug Conjugates: Do They Boost Drug Activity? | Basagni F.; Marotta G.; Rosini M.; Minarini A. | 2023-01-01 | MOLECULES | - | 1.01 Articolo in rivista | 109. Molecules 2023.pdf |
| Radiosynthesis, Preclinical, and Clinical Positron Emission Tomography Studies of Carbon-11 Labeled Endogenous and Natural Exogenous Compounds |
Antonio Shegani, Steven Kealey, Federico Luzi, Filippo Basagni, Joana do Mar Machado, Sevban Dog...̆an Ekici, Alessandra Ferocino, Antony D. Gee,* Salvatore Bongarzone* |
2023-01-01 | CHEMICAL REVIEWS | - | 1.01 Articolo in rivista | ChemRev2023-compresso.pdf; ChemRev2023Correction.pdf |
| Inhibition of β-Amyloid Aggregation in Alzheimer's Disease: The Key Role of (Pro)electrophilic Warheads | Basagni, Filippo; Naldi, Marina; Ginex, Tiziana; Luque, F Javier; Fagiani, Francesca; Lanni, Cris...tina; Iurlo, Matteo; Marcaccio, Massimo; Minarini, Anna; Bartolini, Manuela; Rosini, Michela | 2022-01-01 | ACS MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | acsmedchemlett.2c00410.pdf; ml2c00410_si_001.pdf |
| Nature-Inspired Hybrids (NIH) Improve Proteostasis by Activating Nrf2-Mediated Protective Pathways in Retinal Pigment Epithelial Cells | Koskela, Ali; Manai, Federico; Basagni, Filippo; Liukkonen, Mikko; Rosini, Michela; Govoni, Stefa...no; Monte, Massimo Dal; Smedowski, Adrian; Kaarniranta, Kai; Amadio, Marialaura | 2022-01-01 | ANTIOXIDANTS | - | 1.01 Articolo in rivista | antioxidants-11-01385.pdf |
| Role of Fyn Kinase Inhibitors in Switching Neuroinflammatory Pathways | Marotta, Giambattista; Basagni, Filippo; Rosini, Michela; Minarini, Anna | 2022-01-01 | CURRENT MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | CurrMedChem2022.pdf |
| A nature‐inspired nrf2 activator protects retinal explants from oxidative stress and neurodegeneration | Rossino M.G.; Amato R.; Amadio M.; Rosini M.; Basagni F.; Cammalleri M.; Dal Monte M.; Casini G. | 2021-01-01 | ANTIOXIDANTS | - | 1.01 Articolo in rivista | antioxidants-10-01296-v2.pdf |
| Eye-Light on Age-Related Macular Degeneration: Targeting Nrf2-Pathway as a Novel Therapeutic Strategy for Retinal Pigment Epithelium | Catanzaro M.; Lanni C.; Basagni F.; Rosini M.; Govoni S.; Amadio M. | 2020-01-01 | FRONTIERS IN PHARMACOLOGY | - | 1.01 Articolo in rivista | fphar-11-00844.pdf |
| Functionalized Cannabinoid Subtype 2 Receptor Ligands: Fluorescent, PET, Photochromic and Covalent Molecular Probes | Basagni F.; Rosini M.; Decker M. | 2020-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | CMDC-15-1374.pdf |
| Memantine Derivatives as Multitarget Agents in Alzheimer’s Disease | Marotta G.; Basagni F.; Rosini M.; Minarini A. | 2020-01-01 | MOLECULES | - | 1.01 Articolo in rivista | molecules-25-04005.pdf |
| NRF2 and PPAR-γ Pathways in Oligodendrocyte Progenitors: Focus on Ros Protection, Mitochondrial Biogenesis and Promotion of Cell Differentiation | De Nuccio C.; Bernardo A.; Troiano C.; Brignone M.S.; Falchi M.; Greco A.; Rosini M.; Basagni F.;... Lanni C.; Serafini M.M.; Minghetti L.; Visentin S. | 2020-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-21-07216-v2.pdf |
| Targeting Cytokine Release Through the Differential Modulation of Nrf2 and NF-κB Pathways by Electrophilic/Non-Electrophilic Compounds | Fagiani F.; Catanzaro M.; Buoso E.; Basagni F.; Di Marino D.; Raniolo S.; Amadio M.; Frost E.H.; ...Corsini E.; Racchi M.; Fulop T.; Govoni S.; Rosini M.; Lanni C. | 2020-01-01 | FRONTIERS IN PHARMACOLOGY | - | 1.01 Articolo in rivista | fphar-11-01256.pdf |
| Development of [18F]FAMTO: A novel fluorine-18 labelled positron emission tomography (PET) radiotracer for imaging CYP11B1 and CYP11B2 enzymes in adrenal glands | Bongarzone, Salvatore; Basagni, Filippo; Sementa, Teresa; Singh, Nisha; Gakpetor, Caleb; Faugeras..., Vincent; Bordoloi, Jayanta; Gee, Antony D.* | 2019-01-01 | NUCLEAR MEDICINE AND BIOLOGY | - | 1.01 Articolo in rivista | NuclMedBiol2019.pdf; NuclMedBiol2019_supplementary.docx |
| Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase | Di Paolo, Maria Luisa; Cervelli, Manuela; Mariottini, Paolo; Leonetti, Alessia; Polticelli, Fabio...; Rosini, Michela; Milelli, Andrea; Basagni, Filippo; Venerando, Rina; Agostinelli, Enzo; Minarini, Anna | 2019-01-01 | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | 99. J.Enz. Inhib. Med Chem 2019.pdf |
| Lights and shadows of electrophile signaling: Focus on the Nrf2-Keap1 pathway | Basagni F.; Lanni C.; Minarini A.; Rosini M. | 2019-01-01 | FUTURE MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Merging memantine and ferulic acid to probe connections between NMDA receptors, oxidative stress and amyloid-β peptide in Alzheimer's disease | Rosini M.; Simoni E.; Caporaso R.; Basagni F.; Catanzaro M.; Abu I.F.; Fagiani F.; Fusco F.; Masu...zzo S.; Albani D.; Lanni C.; Mellor I.R.; Minarini A. | 2019-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | EJMECH_11508.pdf |