GUIDOTTI, SERENA
GUIDOTTI, SERENA
DIPARTIMENTO DI SCIENZE MEDICHE E CHIRURGICHE
Spermidine rescues the deregulated autophagic response to oxidative stress of osteoarthritic chondrocytes
2020 Stefania D'Adamo, Silvia Cetrullo, Serena Guidotti, Ylenia Silvestri, Manuela Minguzzi, Spartaco Santi, Luca Cattini, Giuseppe Filardo, Flavio Flamigni, Rosa Maria Borzì
Polyamine supplementation reduces DNA damage in adipose stem cells cultured in 3-D
2019 Minguzzi M.; Guidotti S.; Platano D.; D'Adamo S.; Cetrullo S.; Assirelli E.; Santi S.; Mariani E.; Trisolino G.; Filardo G.; Flamigni F.; Borzi R.M.
Chondroprotective and anti-oxidant activity of spermidine in human chondrocytes
2018 Silvestri, Y.; D'adamo, S.; Cetrullo, S.; Minguzzi, M.; Guidotti, S.; Filardo, G.; Mariani, E.; Borzì, R.; Flamigni, F.
Emerging roles of spermidine in human chondrocyte protection: oxidative stress resistance and induction of autophagy
2017 Silvestri, Y; D'Adamo, S; Cetrullo, S; Minguzzi, M; Guidotti, S; Filardo, G; Mariani, E; Borzi, Rm; Flamigni, F.
Glycogen synthase kinase -3β inhibition leads to mitochondrial dysfunction, extracellular matrix remodelling and terminal differentiation of human chondrocytes.
2017 Minguzzi M., Guidotti S, Platano D, Santi S , Filardo G., Mariani E., Borzì R.M.
Hydroxytyrosol modulates the levels of microRNA-9 and its target sirtuin-1 thereby counteracting oxidative stress-induced chondrocyte death
2017 D'Adamo, S.; Cetrullo, S.; Guidotti, S.; Borzì, R.M.; Flamigni, F
Infrapatellar fat pad-derived mesenchymal stromal cells from osteoarthritis patients: In vitro genetic stability and replicative senescence
2017 Neri, Simona; Guidotti, Serena; Lilli, Nicoletta Libera; Cattini, Luca; Mariani, Erminia
Hydroxytyrosol induces epigenetic changes in chondrocyte response to oxidative stress
2016 D'Adamo, Stefania; Cetrullo, Silvia; Guidotti, Serena; Mariani, Erminia; Borzì, Rosa Maria; Flamigni, Flavio
Hydroxytyrosol prevents chondrocyte death under oxidative stress by inducing autophagy through sirtuin 1-dependent and -independent mechanisms
2016 Cetrullo, Silvia; D'Adamo, Stefania; Guidotti, Serena; Borzì, Rosa Maria; Flamigni, Flavio
Polyamines as endogenous counteractors against DNA damage in adipose derived stem cells cultured in 3-D
2016 Minguzzi, M.; Guidotti, S.; Platano, D.; D’Adamo, S.; Mariani, E.; Trisolino, G.; Filardo, G.; Flamigni, F.; Borzì, R.M
Polyamines as endogenous counteractors against DNA damage in adipose derived stem cells cultured in 3-D.
2016 Minguzzi M., Guidotti S, Platano D., D'Adamo S., Mariani E., Trisolino G., Filardo G., Flamigni F. ,Borzì R.M
GSK3 beta: a key regulator of oxidative stress in 3D-cultures of osteoarthritic chondrocytes
2015 Guidotti, S; Minguzzi, M; Platano, D; Santi, S; Mariani, E; Trisolino, G; Filardo, G; Borzi, Rm
Lithium chloride dependent glycogen synthase kinase 3 inactivation links oxidative DNA damage, hypertrophy and senescence in human articular chondrocytes and reproduces chondrocyte phenotype of obese osteoarthritis patients
2015 Guidotti, Serena; Minguzzi, Manuela; Platano, Daniela; Cattini, Luca; Trisolino, Giovanni; Mariani, Erminia; Borzì, Rosa Maria
microRNA-9 mediates oxidative stress-induced cytotoxicity in chondrocytes by targeting Sirt-1
2015 D’Adamo, S.; Cetrullo, S.; Guidotti, S.; Borzì, R. M.; Flamigni, F.
Spermidine protects human chondrocytes from oxidative stress and reduces cell death by autophagy induction
2015 Guidotti, S.; Cetrullo, S.; D’Adamo, S.; Mariani, E.; Flamigni, F.; Borzì, R. M.
3-HYDROXYTYROSOL PROTECTS CHONDROCYTES AGAINST MICRORNA-9 INCREASED BY OXIDATIVE STRESS
2014 Silvia Cetrullo; Stefania D’Adamo; Annalisa Facchini; Serena Guidotti; Rosa Maria Borzì;Andrea Facchini; Flavio Flamigni
Cell death in human articular chondrocyte: a morpho-functional study in micromass model
2014 Michela Battistelli; Sara Salucci; Eleonora Olivotto; Annalisa Facchini; Manuela Minguzzi; Serena Guidotti; Stefania Pagani; Flavio Flamigni; Rosa Maria Borzì; Andrea Facchini; Elisabetta Falcieri
GSK3β inhibiton in osteoarthritic human primary chondrocytes determines oxidative stress and DNA damage response leading to senescence or apoptosis in different stimulatory contexts.
2014 Manuela Minguzzi, Serena Guidotti, D. Platano, E . Olivotto, A. Facchini L. Cattini, F. Flamigni, G. Trisolino, A. Facchini, R.M. Borzì
Hydroxytyrosol Prevents Increase of Osteoarthritis Markers in Human Chondrocytes Treated with Hydrogen Peroxide or Growth-Related Oncogene α
2014 Annalisa Facchini; Silvia Cetrullo; Stefania D'Adamo; Serena Guidotti; Manuela Minguzzi; Andrea Facchini; Rosa Maria Borzi; Flavio Flamigni
Polyamine delivery as a tool to modulate stem cell differentiation in skeletal tissue engineering
2014 Rosa Maria Borzì;Serena Guidotti;Manuela Minguzzi;Annalisa Facchini;Daniela Platano;Giovanni Trisolino;Giuseppe Filardo;Silvia Cetrullo;Stefania D’Adamo;Claudio Stefanelli;Andrea Facchini;Flavio Flamigni
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Spermidine rescues the deregulated autophagic response to oxidative stress of osteoarthritic chondrocytes | Stefania D'Adamo, Silvia Cetrullo, Serena Guidotti, Ylenia Silvestri, Manuela Minguzzi, Spartaco ...Santi, Luca Cattini, Giuseppe Filardo, Flavio Flamigni, Rosa Maria Borzì | 2020-01-01 | FREE RADICAL BIOLOGY & MEDICINE | - | 1.01 Articolo in rivista | POSTPRINT - Spermidine rescues the deregulated autophagic response to oxidative stress of osteoarthritic chondrocytes.pdf |
| Polyamine supplementation reduces DNA damage in adipose stem cells cultured in 3-D | Minguzzi M.; Guidotti S.; Platano D.; D'Adamo S.; Cetrullo S.; Assirelli E.; Santi S.; Mariani E....; Trisolino G.; Filardo G.; Flamigni F.; Borzi R.M. | 2019-01-01 | SCIENTIFIC REPORTS | - | 1.01 Articolo in rivista | SR s41598-019-50543-z.pdf |
| Chondroprotective and anti-oxidant activity of spermidine in human chondrocytes | Silvestri, Y.; D'adamo, S.; Cetrullo, S.; Minguzzi, M.; Guidotti, S.; Filardo, G.; Mariani, E.; B...orzì, R.; Flamigni, F. | 2018-01-01 | OSTEOARTHRITIS AND CARTILAGE | ELSEVIER SCI LTD | 4.02 Riassunto (Abstract) | - |
| Emerging roles of spermidine in human chondrocyte protection: oxidative stress resistance and induction of autophagy | Silvestri, Y; D'Adamo, S; Cetrullo, S; Minguzzi, M; Guidotti, S; Filardo, G; Mariani, E; Borzi, R...m; Flamigni, F. | 2017-01-01 | THE FEBS JOURNAL | WILEY | 4.02 Riassunto (Abstract) | - |
| Glycogen synthase kinase -3β inhibition leads to mitochondrial dysfunction, extracellular matrix remodelling and terminal differentiation of human chondrocytes. | Minguzzi M., Guidotti S, Platano D, Santi S , Filardo G., Mariani E., Borzì R.M. | 2017-01-01 | - | CSSI, Cell Stress Society International | 4.01 Contributo in Atti di convegno | - |
| Hydroxytyrosol modulates the levels of microRNA-9 and its target sirtuin-1 thereby counteracting oxidative stress-induced chondrocyte death | D'Adamo, S.; Cetrullo, S.; Guidotti, S.; Borzì, R.M.; Flamigni, F | 2017-01-01 | OSTEOARTHRITIS AND CARTILAGE | - | 1.01 Articolo in rivista | - |
| Infrapatellar fat pad-derived mesenchymal stromal cells from osteoarthritis patients: In vitro genetic stability and replicative senescence | Neri, Simona; Guidotti, Serena; Lilli, Nicoletta Libera; Cattini, Luca; Mariani, Erminia | 2017-01-01 | JOURNAL OF ORTHOPAEDIC RESEARCH | - | 1.01 Articolo in rivista | - |
| Hydroxytyrosol induces epigenetic changes in chondrocyte response to oxidative stress | D'Adamo, Stefania; Cetrullo, Silvia; Guidotti, Serena; Mariani, Erminia; Borzì, Rosa Maria; Flami...gni, Flavio | 2016-01-01 | JOURNAL OF INTERNATIONAL SOCIETY OF ANTIOXIDANTS IN NUTRITION & HEALTH | - | 4.02 Riassunto (Abstract) | - |
| Hydroxytyrosol prevents chondrocyte death under oxidative stress by inducing autophagy through sirtuin 1-dependent and -independent mechanisms | Cetrullo, Silvia; D'Adamo, Stefania; Guidotti, Serena; Borzì, Rosa Maria; Flamigni, Flavio | 2016-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS | - | 1.01 Articolo in rivista | hydroxy_2016.pdf |
| Polyamines as endogenous counteractors against DNA damage in adipose derived stem cells cultured in 3-D | Minguzzi, M.; Guidotti, S.; Platano, D.; D’Adamo, S.; Mariani, E.; Trisolino, G.; Filardo, G.; Fl...amigni, F.; Borzì, R.M | 2016-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Polyamines as endogenous counteractors against DNA damage in adipose derived stem cells cultured in 3-D. | Minguzzi M., Guidotti S, Platano D., D'Adamo S., Mariani E., Trisolino G., Filardo G., Flamigni ...F. ,Borzì R.M | 2016-01-01 | - | - | 4.03 Poster | - |
| GSK3 beta: a key regulator of oxidative stress in 3D-cultures of osteoarthritic chondrocytes | Guidotti, S; Minguzzi, M; Platano, D; Santi, S; Mariani, E; Trisolino, G; Filardo, G; Borzi, Rm | 2015-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Lithium chloride dependent glycogen synthase kinase 3 inactivation links oxidative DNA damage, hypertrophy and senescence in human articular chondrocytes and reproduces chondrocyte phenotype of obese osteoarthritis patients | Guidotti, Serena; Minguzzi, Manuela; Platano, Daniela; Cattini, Luca; Trisolino, Giovanni; Marian...i, Erminia; Borzì, Rosa Maria | 2015-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | PlosOne 2015 Borzi.pdf |
| microRNA-9 mediates oxidative stress-induced cytotoxicity in chondrocytes by targeting Sirt-1 | D’Adamo, S.; Cetrullo, S.; Guidotti, S.; Borzì, R. M.; Flamigni, F. | 2015-01-01 | FEBS JOURNAL. S | - | 4.02 Riassunto (Abstract) | - |
| Spermidine protects human chondrocytes from oxidative stress and reduces cell death by autophagy induction | Guidotti, S.; Cetrullo, S.; D’Adamo, S.; Mariani, E.; Flamigni, F.; Borzì, R. M. | 2015-01-01 | FEBS JOURNAL. S | - | 4.02 Riassunto (Abstract) | - |
| 3-HYDROXYTYROSOL PROTECTS CHONDROCYTES AGAINST MICRORNA-9 INCREASED BY OXIDATIVE STRESS | Silvia Cetrullo; Stefania D’Adamo; Annalisa Facchini; Serena Guidotti; Rosa Maria Borzì;Andrea Fa...cchini; Flavio Flamigni | 2014-01-01 | - | Pisa University Press | 4.02 Riassunto (Abstract) | - |
| Cell death in human articular chondrocyte: a morpho-functional study in micromass model | Michela Battistelli; Sara Salucci; Eleonora Olivotto; Annalisa Facchini; Manuela Minguzzi; Serena... Guidotti; Stefania Pagani; Flavio Flamigni; Rosa Maria Borzì; Andrea Facchini; Elisabetta Falcieri | 2014-01-01 | APOPTOSIS | - | 1.01 Articolo in rivista | - |
| GSK3β inhibiton in osteoarthritic human primary chondrocytes determines oxidative stress and DNA damage response leading to senescence or apoptosis in different stimulatory contexts. | Manuela Minguzzi, Serena Guidotti, D. Platano, E . Olivotto, A. Facchini L. Cattini, F. Flamigni..., G. Trisolino, A. Facchini, R.M. Borzì | 2014-01-01 | - | - | 4.01 Contributo in Atti di convegno | - |
| Hydroxytyrosol Prevents Increase of Osteoarthritis Markers in Human Chondrocytes Treated with Hydrogen Peroxide or Growth-Related Oncogene α | Annalisa Facchini; Silvia Cetrullo; Stefania D'Adamo; Serena Guidotti; Manuela Minguzzi; Andrea F...acchini; Rosa Maria Borzi; Flavio Flamigni | 2014-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | journal.pone.0109724.pdf |
| Polyamine delivery as a tool to modulate stem cell differentiation in skeletal tissue engineering | Rosa Maria Borzì;Serena Guidotti;Manuela Minguzzi;Annalisa Facchini;Daniela Platano;Giovanni Tris...olino;Giuseppe Filardo;Silvia Cetrullo;Stefania D’Adamo;Claudio Stefanelli;Andrea Facchini;Flavio Flamigni | 2014-01-01 | AMINO ACIDS | - | 1.01 Articolo in rivista | - |