CRIS Current Research Information System

TONELLI, ROBERTO
 Distribuzione geografica
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Continente #
NA - Nord America 2.166
EU - Europa 2.047
AS - Asia 754
AF - Africa 88
SA - Sud America 2
Totale 5.057
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Nazione #
US - Stati Uniti d'America 2.156
IT - Italia 679
GB - Regno Unito 478
CN - Cina 252
DE - Germania 191
VN - Vietnam 183
SE - Svezia 181
SG - Singapore 176
UA - Ucraina 138
IN - India 91
IE - Irlanda 67
FR - Francia 64
CH - Svizzera 62
RU - Federazione Russa 55
ZA - Sudafrica 31
EE - Estonia 26
FI - Finlandia 24
TG - Togo 23
CI - Costa d'Avorio 17
BE - Belgio 16
JO - Giordania 16
PT - Portogallo 15
GR - Grecia 13
NL - Olanda 12
SC - Seychelles 11
BG - Bulgaria 10
CA - Canada 9
JP - Giappone 8
BD - Bangladesh 7
ES - Italia 7
IR - Iran 7
ID - Indonesia 4
NG - Nigeria 4
HK - Hong Kong 3
HR - Croazia 2
MU - Mauritius 2
PE - Perù 2
TR - Turchia 2
UZ - Uzbekistan 2
AT - Austria 1
CZ - Repubblica Ceca 1
GL - Groenlandia 1
HU - Ungheria 1
KR - Corea 1
MD - Moldavia 1
MY - Malesia 1
NO - Norvegia 1
PH - Filippine 1
PL - Polonia 1
RO - Romania 1
Totale 5.057
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Città #
Southend 428
Chandler 241
Fairfield 218
Parma 200
Ashburn 151
Singapore 151
Dong Ket 141
Woodbridge 135
Santa Clara 130
Seattle 119
Wilmington 109
Jacksonville 96
Ann Arbor 92
Cambridge 89
Princeton 88
Houston 82
Bologna 74
Dublin 65
Turin 57
Boardman 54
Bern 53
Nanjing 43
Padova 39
Westminster 39
Milan 31
Berlin 30
Lomé 23
Reggio Emilia 23
Helsinki 22
Jinan 21
Beijing 20
Mülheim 19
Saint Petersburg 18
San Diego 18
Abidjan 17
Redmond 17
Amman 16
Brussels 15
Rome 15
Shenyang 15
Hebei 12
Medford 12
Nanchang 12
Mahé 11
Mountain View 11
Changsha 10
San Giuliano Milanese 10
Sofia 10
Tianjin 10
Los Angeles 9
Jiaxing 8
Norwalk 8
Taizhou 8
Tokyo 8
Zhengzhou 8
Dhaka 7
Guangzhou 7
Kuban 7
Taiyuan 7
Toronto 7
Verona 7
Dearborn 6
New York 6
San Felice sul Panaro 6
Shanghai 6
Taglio Di Po 6
Bremen 5
Casorezzo 5
Des Moines 5
Florence 5
Hangzhou 5
London 5
Redwood City 5
Washington 5
Wenzhou 5
Abeokuta 4
Cornaredo 4
Falkenstein 4
Jakarta 4
Monmouth Junction 4
Teià 4
Amsterdam 3
Boydton 3
Falls Church 3
Formigine 3
Haikou 3
Hyderabad 3
Leipzig 3
Madrid 3
Nardò 3
Phoenix 3
San Venanzo 3
Shijiazhuang 3
Atlanta 2
Bollate 2
Capoterra 2
Casalmaiocco 2
Catania 2
Catanzaro 2
Chicago 2
Totale 3.552
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Nome #
Antigene MYCN Silencing by BGA002 Inhibits SCLC Progression Blocking mTOR Pathway and Overcomes Multidrug Resistance 333
Anti-gene Peptide Nucleic Acid (PNA) specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis. 170
Antitumor Activity of Sustained N-Myc Reduction in Rhabdomyosarcomas and Transcriptional Block by Antigene Therapy 163
A novel MYCN-specific antigene oligonucleotide deregulates mitochondria and inhibits tumor growth in MYCN-amplified neuroblastoma 158
A Peptide Nucleic Acid Embedding a Pseudopeptide Nuclear Localization Sequence in the Backbone Behaves as a Peptide Mimic 152
The MYCN inhibitor BGA002 restores the retinoic acid response leading to differentiation or apoptosis by the mTOR block in MYCN-amplified neuroblastoma 146
Chitosan nanoparticles for siRNA delivery: influence of nanoparticle composition on gene silencing efficiency 140
In vivo bioluminescence imaging of murine xenograft cancer models with a red-shifted thermostable luciferase. 140
THE P53 REGULATORY GENE MDM2 IS A DIRECT TRANSCRIPTIONAL TARGET OF MYCN IN NEUROBLASTOMA 136
p21Waf1/Cip1 is a common target induced by short-chain fatty acid HDAC inhibitors (valproic acid, tributyrin and sodium butyrate) in neuroblastoma cells 133
The MYCN oncogene as a specific and selective drug target for peripheral and central nervous system tumors. 129
Targeted inhibition of NMYC by peptide nucleic acid in N-myc amplified human neuroblastoma cells: cell-cycle inhibition with induction of neuronal cell differentiation and apoptosis 129
Circular dichroism study of DNA binding by a potential anticancer peptide nucleic acid targeted against the MYCN oncogene. 125
Feasibility and safety of adoptive immunotherapy with ex vivogenerated autologous, cytotoxic T lymphocytes in patients with solid tumor 123
ArgBP2, encoding a negative regulator of ABL, is fused to MLL in a case of infant M5 acute myeloid leukemia involving 4q35 and 11q23. 117
Analisi in vitro ed in vivo dell'attività anti-tumorale dopo inibizione specifica di MYCN mediante PNA-NLS anti-gene nel rabdomiosarcoma umano 116
Identification of two MLL-MLLT3 (alias MLL-AF9) chimeric transcripts in the MOLM-13 cell line. 115
MYCN is a novel oncogenic target in pediatric T-cell Acute Lymphoblastic Leukemia 114
G1 Cell-Cycle Arrest and Apoptosis by Histone Deacetylase Inhibition in MLL-AF9 Acute Myeloid Leukemia Cells Is MLL-AF9 Independent 111
METHOD FOR SELECTIVE INHIBITION OF HUMAN N-MYC GENE IN N-MYC EXPRESSING TUMORS THROUGH ANTISENSE AND ANTIGEN PEPTIDO-NUCLEIC ACIDS (PNA) 110
G1 cell-cycle arrest and apoptosis by histone deacetylase inhibition in MLL-AF9 acute myeloid leukemia cells is p21 dependent and MLL-AF9 independent 110
Expression of BEX1 in acute myeloid leukemia with MLL rearrangements 109
EX VIVO GENERATION AND EXPANSION OF ANTI-TUMOR CYTOTOXIC T-CELL LINES DERIVED FROM PATIENTS OR THEIR HLA-IDENTICAL SIBLING 107
FDG small animal PET permits early detection of malignant cells in a xenograft murine model. 106
Generation and characterization of bioluminescent xenograft mouse models of MLL-related acute leukemias and in vivo evaluation of luciferase-targeting siRNA nanoparticles 106
Transient suppression of MLH1 allows effective single-nucleotide substitution by single-stranded DNA oligonucleotides 106
Inibizione specifica di MYCN e MYC mediante PNA-NLS anti-gene in cellule di medulloblastoma umano: caratterizzazione dell'attività anti-tumorale 103
Sulforaphane induces apoptosis in rhabdomyosarcoma and restores TRAIL-sensitivity in the aggressive alveolar subtype leading to tumor elimination in mice. 100
Precoce predittività di attecchimento midollare dopo trapianto allogenico di cellule staminali emopoietiche in pazienti pediatrici mediante valutazione del chimerismo emopoietico con metodo multiplex polymerase chain reaction 99
Trisomy 11 with MLL-PTD in a case of infant AML M0 96
Down-regulation of HOXA4, HOXA7, HOXA10, HOXA11 and MEIS1 during monocyte-macrophage differentiation in THP-1 cells 96
Molecular Imaging of Neuroblastoma Progression in TH-MYCN Transgenic Mice 96
DOWN- REGULATION OF MLL-AF9,MLL,HOXA9,HOXA10, AND MEIS1 EXPRESSION IS NOT OBLIGATORY FOR MONOCYTE- MACROPHAGE MATURATION IN AML -M5 CELL LINES CARRYNG t(9;11)(p22;q23) 94
null 94
Inibizione specifica di MYCN mediante PNA-NLS anti gene in cellule di medullobastoma umano:caratterizzazione dellattività anti-tumorale 92
Growth Inhibition and Proapoptotic Activity Induction by IIF and Valproic Acid on RA-resistant Leukemia Cells. 91
Identificazione del primo caso di trisomia 11 e partial tandem duplication del gene MLL in una leucemia acuta mieloide (LAM) MO da paziente Infant 90
Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma 90
Un modello in vivo per la valutazione della terapia anti-gene PNA-mediata nel neuroblastoma e altre patologie oncologiche con sovraespressione di N-myc. 90
Mutational Screening of Transforming Growth Factor Beta2 (TGF-beta 2) Gene in patients with congenital Thrombocytopaenia with Absent Radii (TAR). 89
valutazione preclinica della terapia epigenetica con inibitori delle iston-deacetilasi ( acido valproico) e dna-metiltransferasi ( decitabina ) in leucemie mieloidi acute con riarrangiamenti di MLL 82
Expression of T cell receptor alpha gene (TCRA) in human rhabdomyosarcoma and other musculo-skeletal sarcomas. 70
MYCN Drives a Tumor Immunosuppressive Environment Which Impacts Survival in Neuroblastoma 64
MYCN Impact on High-Risk Neuroblastoma: From Diagnosis and Prognosis to Targeted Treatment 44
Precision Anti-Cancer Medicines by Oligonucleotide Therapeutics in Clinical Research Targeting Undruggable Proteins and Non-Coding RNAs 42
Preclinical Pharmacokinetics in Tumors and Normal Tissues of the Antigene PNA Oligonucleotide MYCN-Inhibitor BGA002 16
Totale 5.142
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Categoria #
all - tutte 12.907
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 12.907
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020710 0 0 0 0 0 110 137 149 136 92 32 54
2020/2021632 117 44 8 23 16 44 9 34 67 32 33 205
2021/2022820 71 26 79 51 74 50 14 51 35 33 173 163
2022/20231.039 112 122 48 106 74 67 59 54 169 36 95 97
2023/2024403 32 49 25 35 26 76 9 29 10 34 28 50
2024/2025703 57 149 156 98 201 42 0 0 0 0 0 0
Totale 5.142