CRIS Current Research Information System

TONELLI, ROBERTO
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 1.989
EU - Europa 1.934
AS - Asia 630
AF - Africa 88
SA - Sud America 2
Totale 4.643
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 1.981
IT - Italia 599
GB - Regno Unito 477
CN - Cina 189
DE - Germania 187
VN - Vietnam 183
SE - Svezia 181
UA - Ucraina 138
SG - Singapore 124
IN - India 91
IE - Irlanda 67
FR - Francia 64
CH - Svizzera 61
RU - Federazione Russa 51
ZA - Sudafrica 31
EE - Estonia 26
TG - Togo 23
CI - Costa d'Avorio 17
BE - Belgio 16
JO - Giordania 16
PT - Portogallo 15
GR - Grecia 13
SC - Seychelles 11
BG - Bulgaria 10
FI - Finlandia 10
JP - Giappone 8
BD - Bangladesh 7
CA - Canada 7
NL - Olanda 7
IR - Iran 4
NG - Nigeria 4
ES - Italia 3
HR - Croazia 2
MU - Mauritius 2
PE - Perù 2
TR - Turchia 2
UZ - Uzbekistan 2
AT - Austria 1
CZ - Repubblica Ceca 1
GL - Groenlandia 1
HK - Hong Kong 1
HU - Ungheria 1
KR - Corea 1
MD - Moldavia 1
MY - Malesia 1
NO - Norvegia 1
PH - Filippine 1
PL - Polonia 1
RO - Romania 1
Totale 4.643
Salva come PNG Salva come JPEG
Città #
Southend 428
Chandler 241
Fairfield 218
Parma 152
Ashburn 151
Dong Ket 141
Woodbridge 135
Seattle 119
Wilmington 109
Singapore 101
Jacksonville 96
Ann Arbor 92
Cambridge 89
Princeton 88
Houston 82
Bologna 71
Dublin 65
Turin 57
Bern 53
Nanjing 43
Padova 39
Westminster 39
Berlin 30
Milan 29
Lomé 23
Reggio Emilia 23
Jinan 21
Mülheim 19
Saint Petersburg 18
San Diego 18
Abidjan 17
Beijing 17
Redmond 17
Amman 16
Brussels 15
Shenyang 15
Rome 14
Hebei 12
Medford 12
Nanchang 12
Mahé 11
Mountain View 11
Changsha 10
San Giuliano Milanese 10
Sofia 10
Boardman 9
Los Angeles 9
Santa Clara 9
Tianjin 9
Helsinki 8
Jiaxing 8
Norwalk 8
Taizhou 8
Tokyo 8
Dhaka 7
Kuban 7
Verona 7
Dearborn 6
New York 6
San Felice sul Panaro 6
Taglio Di Po 6
Taiyuan 6
Zhengzhou 6
Bremen 5
Casorezzo 5
Des Moines 5
Florence 5
London 5
Redwood City 5
Toronto 5
Washington 5
Abeokuta 4
Cornaredo 4
Monmouth Junction 4
Amsterdam 3
Boydton 3
Falls Church 3
Formigine 3
Guangzhou 3
Haikou 3
Hangzhou 3
Hyderabad 3
Leipzig 3
Madrid 3
Nardò 3
San Venanzo 3
Atlanta 2
Bollate 2
Capoterra 2
Casalmaiocco 2
Catania 2
Catanzaro 2
Chicago 2
Den Haag 2
Edinburgh 2
Forlì 2
Frankfurt am Main 2
Fuzhou 2
Guesnain 2
Jesolo 2
Totale 3.238
Salva come PNG Salva come JPEG
Nome #
Antigene MYCN Silencing by BGA002 Inhibits SCLC Progression Blocking mTOR Pathway and Overcomes Multidrug Resistance 247
Anti-gene Peptide Nucleic Acid (PNA) specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis. 162
Antitumor Activity of Sustained N-Myc Reduction in Rhabdomyosarcomas and Transcriptional Block by Antigene Therapy 155
A novel MYCN-specific antigene oligonucleotide deregulates mitochondria and inhibits tumor growth in MYCN-amplified neuroblastoma 149
A Peptide Nucleic Acid Embedding a Pseudopeptide Nuclear Localization Sequence in the Backbone Behaves as a Peptide Mimic 145
The MYCN inhibitor BGA002 restores the retinoic acid response leading to differentiation or apoptosis by the mTOR block in MYCN-amplified neuroblastoma 135
In vivo bioluminescence imaging of murine xenograft cancer models with a red-shifted thermostable luciferase. 131
THE P53 REGULATORY GENE MDM2 IS A DIRECT TRANSCRIPTIONAL TARGET OF MYCN IN NEUROBLASTOMA 128
p21Waf1/Cip1 is a common target induced by short-chain fatty acid HDAC inhibitors (valproic acid, tributyrin and sodium butyrate) in neuroblastoma cells 127
The MYCN oncogene as a specific and selective drug target for peripheral and central nervous system tumors. 124
Chitosan nanoparticles for siRNA delivery: influence of nanoparticle composition on gene silencing efficiency 121
Targeted inhibition of NMYC by peptide nucleic acid in N-myc amplified human neuroblastoma cells: cell-cycle inhibition with induction of neuronal cell differentiation and apoptosis 120
Feasibility and safety of adoptive immunotherapy with ex vivogenerated autologous, cytotoxic T lymphocytes in patients with solid tumor 118
Circular dichroism study of DNA binding by a potential anticancer peptide nucleic acid targeted against the MYCN oncogene. 117
ArgBP2, encoding a negative regulator of ABL, is fused to MLL in a case of infant M5 acute myeloid leukemia involving 4q35 and 11q23. 111
Identification of two MLL-MLLT3 (alias MLL-AF9) chimeric transcripts in the MOLM-13 cell line. 110
Analisi in vitro ed in vivo dell'attività anti-tumorale dopo inibizione specifica di MYCN mediante PNA-NLS anti-gene nel rabdomiosarcoma umano 108
MYCN is a novel oncogenic target in pediatric T-cell Acute Lymphoblastic Leukemia 107
Expression of BEX1 in acute myeloid leukemia with MLL rearrangements 105
METHOD FOR SELECTIVE INHIBITION OF HUMAN N-MYC GENE IN N-MYC EXPRESSING TUMORS THROUGH ANTISENSE AND ANTIGEN PEPTIDO-NUCLEIC ACIDS (PNA) 105
G1 Cell-Cycle Arrest and Apoptosis by Histone Deacetylase Inhibition in MLL-AF9 Acute Myeloid Leukemia Cells Is MLL-AF9 Independent 105
G1 cell-cycle arrest and apoptosis by histone deacetylase inhibition in MLL-AF9 acute myeloid leukemia cells is p21 dependent and MLL-AF9 independent 105
EX VIVO GENERATION AND EXPANSION OF ANTI-TUMOR CYTOTOXIC T-CELL LINES DERIVED FROM PATIENTS OR THEIR HLA-IDENTICAL SIBLING 102
FDG small animal PET permits early detection of malignant cells in a xenograft murine model. 99
Generation and characterization of bioluminescent xenograft mouse models of MLL-related acute leukemias and in vivo evaluation of luciferase-targeting siRNA nanoparticles 99
Transient suppression of MLH1 allows effective single-nucleotide substitution by single-stranded DNA oligonucleotides 99
Inibizione specifica di MYCN e MYC mediante PNA-NLS anti-gene in cellule di medulloblastoma umano: caratterizzazione dell'attività anti-tumorale 95
Precoce predittività di attecchimento midollare dopo trapianto allogenico di cellule staminali emopoietiche in pazienti pediatrici mediante valutazione del chimerismo emopoietico con metodo multiplex polymerase chain reaction 94
null 94
Sulforaphane induces apoptosis in rhabdomyosarcoma and restores TRAIL-sensitivity in the aggressive alveolar subtype leading to tumor elimination in mice. 92
Molecular Imaging of Neuroblastoma Progression in TH-MYCN Transgenic Mice 91
DOWN- REGULATION OF MLL-AF9,MLL,HOXA9,HOXA10, AND MEIS1 EXPRESSION IS NOT OBLIGATORY FOR MONOCYTE- MACROPHAGE MATURATION IN AML -M5 CELL LINES CARRYNG t(9;11)(p22;q23) 90
Trisomy 11 with MLL-PTD in a case of infant AML M0 90
Down-regulation of HOXA4, HOXA7, HOXA10, HOXA11 and MEIS1 during monocyte-macrophage differentiation in THP-1 cells 90
Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma 85
Inibizione specifica di MYCN mediante PNA-NLS anti gene in cellule di medullobastoma umano:caratterizzazione dellattività anti-tumorale 82
Identificazione del primo caso di trisomia 11 e partial tandem duplication del gene MLL in una leucemia acuta mieloide (LAM) MO da paziente Infant 82
Mutational Screening of Transforming Growth Factor Beta2 (TGF-beta 2) Gene in patients with congenital Thrombocytopaenia with Absent Radii (TAR). 81
Un modello in vivo per la valutazione della terapia anti-gene PNA-mediata nel neuroblastoma e altre patologie oncologiche con sovraespressione di N-myc. 81
valutazione preclinica della terapia epigenetica con inibitori delle iston-deacetilasi ( acido valproico) e dna-metiltransferasi ( decitabina ) in leucemie mieloidi acute con riarrangiamenti di MLL 78
Growth Inhibition and Proapoptotic Activity Induction by IIF and Valproic Acid on RA-resistant Leukemia Cells. 78
Expression of T cell receptor alpha gene (TCRA) in human rhabdomyosarcoma and other musculo-skeletal sarcomas. 65
MYCN Drives a Tumor Immunosuppressive Environment Which Impacts Survival in Neuroblastoma 58
MYCN Impact on High-Risk Neuroblastoma: From Diagnosis and Prognosis to Targeted Treatment 33
Precision Anti-Cancer Medicines by Oligonucleotide Therapeutics in Clinical Research Targeting Undruggable Proteins and Non-Coding RNAs 31
Preclinical Pharmacokinetics in Tumors and Normal Tissues of the Antigene PNA Oligonucleotide MYCN-Inhibitor BGA002 2
Totale 4.726
Salva come PNG Salva come JPEG
Categoria #
all - tutte 11.721
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 11.721
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020902 0 0 19 72 101 110 137 149 136 92 32 54
2020/2021632 117 44 8 23 16 44 9 34 67 32 33 205
2021/2022820 71 26 79 51 74 50 14 51 35 33 173 163
2022/20231.039 112 122 48 106 74 67 59 54 169 36 95 97
2023/2024403 32 49 25 35 26 76 9 29 10 34 28 50
2024/2025287 57 149 81 0 0 0 0 0 0 0 0 0
Totale 4.726