CRIS Current Research Information System

TONELLI, ROBERTO
 Distribuzione geografica
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Continente #
EU - Europa 2.476
NA - Nord America 2.454
AS - Asia 1.976
AF - Africa 123
SA - Sud America 118
Totale 7.147
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Nazione #
US - Stati Uniti d'America 2.431
IT - Italia 889
CN - Cina 651
SG - Singapore 572
GB - Regno Unito 491
VN - Vietnam 298
DE - Germania 234
SE - Svezia 182
HK - Hong Kong 180
UA - Ucraina 140
IN - India 112
RU - Federazione Russa 94
BR - Brasile 91
FR - Francia 81
NL - Olanda 78
IE - Irlanda 68
CH - Svizzera 63
KR - Corea 59
JP - Giappone 37
FI - Finlandia 36
ZA - Sudafrica 34
CI - Costa d'Avorio 29
SC - Seychelles 27
EE - Estonia 26
TG - Togo 23
BE - Belgio 20
JO - Giordania 16
PT - Portogallo 15
AR - Argentina 13
GR - Grecia 13
BD - Bangladesh 11
CA - Canada 11
BG - Bulgaria 10
ES - Italia 10
AT - Austria 8
IR - Iran 7
EC - Ecuador 6
MX - Messico 6
PL - Polonia 6
ID - Indonesia 5
NG - Nigeria 4
PK - Pakistan 4
UZ - Uzbekistan 4
CL - Cile 3
KZ - Kazakistan 3
LT - Lituania 3
PE - Perù 3
AZ - Azerbaigian 2
CZ - Repubblica Ceca 2
DO - Repubblica Dominicana 2
HR - Croazia 2
IQ - Iraq 2
MU - Mauritius 2
PH - Filippine 2
TH - Thailandia 2
TN - Tunisia 2
TR - Turchia 2
AE - Emirati Arabi Uniti 1
AM - Armenia 1
CO - Colombia 1
GL - Groenlandia 1
GT - Guatemala 1
HU - Ungheria 1
IL - Israele 1
MA - Marocco 1
MD - Moldavia 1
MK - Macedonia 1
MY - Malesia 1
NO - Norvegia 1
PA - Panama 1
RO - Romania 1
SA - Arabia Saudita 1
SV - El Salvador 1
TW - Taiwan 1
TZ - Tanzania 1
VE - Venezuela 1
YE - Yemen 1
Totale 7.147
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Città #
Southend 428
Singapore 357
Chandler 241
Ashburn 231
Parma 227
Fairfield 218
Hong Kong 179
Hefei 172
Dong Ket 141
Santa Clara 139
Woodbridge 135
Bologna 128
Seattle 125
Wilmington 110
Jacksonville 96
Ann Arbor 92
Cambridge 89
Princeton 88
Houston 82
Beijing 78
Dublin 66
Seoul 58
Turin 58
Boardman 55
Milan 54
Bern 53
Nanjing 44
Dallas 41
Padova 39
Westminster 39
Ho Chi Minh City 38
Los Angeles 36
Reggio Emilia 36
Tokyo 35
Berlin 30
Abidjan 29
Hanoi 28
Helsinki 25
Lomé 23
Jinan 21
Rome 20
Buffalo 19
Mülheim 19
Bengaluru 18
Brussels 18
Saint Petersburg 18
San Diego 18
Redmond 17
Amman 16
Des Moines 15
Shenyang 15
Changsha 14
Redondo Beach 14
Frankfurt am Main 12
Hebei 12
Medford 12
Nanchang 12
Senago 12
Mahé 11
Mountain View 11
Shanghai 11
Tianjin 11
Zhengzhou 11
Falkenstein 10
Guangzhou 10
Munich 10
Nuremberg 10
San Giuliano Milanese 10
Sofia 10
New York 9
Verona 9
Council Bluffs 8
Jiaxing 8
Norwalk 8
Taizhou 8
Brooklyn 7
Dhaka 7
Hangzhou 7
Kuban 7
London 7
Rio de Janeiro 7
São Paulo 7
Taiyuan 7
Toronto 7
Turku 7
Dearborn 6
Haiphong 6
San Felice sul Panaro 6
Taglio Di Po 6
Yubileyny 6
Amsterdam 5
Bremen 5
Casorezzo 5
Chicago 5
Düsseldorf 5
Florence 5
Redwood City 5
Vienna 5
Warsaw 5
Washington 5
Totale 4.760
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Nome #
Antigene MYCN Silencing by BGA002 Inhibits SCLC Progression Blocking mTOR Pathway and Overcomes Multidrug Resistance 551
Anti-gene Peptide Nucleic Acid (PNA) specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis. 232
A novel MYCN-specific antigene oligonucleotide deregulates mitochondria and inhibits tumor growth in MYCN-amplified neuroblastoma 220
The MYCN inhibitor BGA002 restores the retinoic acid response leading to differentiation or apoptosis by the mTOR block in MYCN-amplified neuroblastoma 201
Antitumor Activity of Sustained N-Myc Reduction in Rhabdomyosarcomas and Transcriptional Block by Antigene Therapy 198
p21Waf1/Cip1 is a common target induced by short-chain fatty acid HDAC inhibitors (valproic acid, tributyrin and sodium butyrate) in neuroblastoma cells 191
THE P53 REGULATORY GENE MDM2 IS A DIRECT TRANSCRIPTIONAL TARGET OF MYCN IN NEUROBLASTOMA 182
Chitosan nanoparticles for siRNA delivery: influence of nanoparticle composition on gene silencing efficiency 179
A Peptide Nucleic Acid Embedding a Pseudopeptide Nuclear Localization Sequence in the Backbone Behaves as a Peptide Mimic 176
In vivo bioluminescence imaging of murine xenograft cancer models with a red-shifted thermostable luciferase. 174
The MYCN oncogene as a specific and selective drug target for peripheral and central nervous system tumors. 169
Targeted inhibition of NMYC by peptide nucleic acid in N-myc amplified human neuroblastoma cells: cell-cycle inhibition with induction of neuronal cell differentiation and apoptosis 163
MYCN is a novel oncogenic target in pediatric T-cell Acute Lymphoblastic Leukemia 158
Feasibility and safety of adoptive immunotherapy with ex vivogenerated autologous, cytotoxic T lymphocytes in patients with solid tumor 154
METHOD FOR SELECTIVE INHIBITION OF HUMAN N-MYC GENE IN N-MYC EXPRESSING TUMORS THROUGH ANTISENSE AND ANTIGEN PEPTIDO-NUCLEIC ACIDS (PNA) 152
Identification of two MLL-MLLT3 (alias MLL-AF9) chimeric transcripts in the MOLM-13 cell line. 151
Expression of BEX1 in acute myeloid leukemia with MLL rearrangements 149
G1 Cell-Cycle Arrest and Apoptosis by Histone Deacetylase Inhibition in MLL-AF9 Acute Myeloid Leukemia Cells Is MLL-AF9 Independent 145
Circular dichroism study of DNA binding by a potential anticancer peptide nucleic acid targeted against the MYCN oncogene. 145
MYCN Impact on High-Risk Neuroblastoma: From Diagnosis and Prognosis to Targeted Treatment 144
Analisi in vitro ed in vivo dell'attività anti-tumorale dopo inibizione specifica di MYCN mediante PNA-NLS anti-gene nel rabdomiosarcoma umano 144
Transient suppression of MLH1 allows effective single-nucleotide substitution by single-stranded DNA oligonucleotides 140
Sulforaphane induces apoptosis in rhabdomyosarcoma and restores TRAIL-sensitivity in the aggressive alveolar subtype leading to tumor elimination in mice. 138
Precision Anti-Cancer Medicines by Oligonucleotide Therapeutics in Clinical Research Targeting Undruggable Proteins and Non-Coding RNAs 137
Trisomy 11 with MLL-PTD in a case of infant AML M0 137
Generation and characterization of bioluminescent xenograft mouse models of MLL-related acute leukemias and in vivo evaluation of luciferase-targeting siRNA nanoparticles 137
Preclinical Pharmacokinetics in Tumors and Normal Tissues of the Antigene PNA Oligonucleotide MYCN-Inhibitor BGA002 136
Inibizione specifica di MYCN e MYC mediante PNA-NLS anti-gene in cellule di medulloblastoma umano: caratterizzazione dell'attività anti-tumorale 134
DOWN- REGULATION OF MLL-AF9,MLL,HOXA9,HOXA10, AND MEIS1 EXPRESSION IS NOT OBLIGATORY FOR MONOCYTE- MACROPHAGE MATURATION IN AML -M5 CELL LINES CARRYNG t(9;11)(p22;q23) 133
ArgBP2, encoding a negative regulator of ABL, is fused to MLL in a case of infant M5 acute myeloid leukemia involving 4q35 and 11q23. 133
Precoce predittività di attecchimento midollare dopo trapianto allogenico di cellule staminali emopoietiche in pazienti pediatrici mediante valutazione del chimerismo emopoietico con metodo multiplex polymerase chain reaction 132
Down-regulation of HOXA4, HOXA7, HOXA10, HOXA11 and MEIS1 during monocyte-macrophage differentiation in THP-1 cells 131
Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma 131
G1 cell-cycle arrest and apoptosis by histone deacetylase inhibition in MLL-AF9 acute myeloid leukemia cells is p21 dependent and MLL-AF9 independent 128
Molecular Imaging of Neuroblastoma Progression in TH-MYCN Transgenic Mice 127
FDG small animal PET permits early detection of malignant cells in a xenograft murine model. 126
Growth Inhibition and Proapoptotic Activity Induction by IIF and Valproic Acid on RA-resistant Leukemia Cells. 125
EX VIVO GENERATION AND EXPANSION OF ANTI-TUMOR CYTOTOXIC T-CELL LINES DERIVED FROM PATIENTS OR THEIR HLA-IDENTICAL SIBLING 123
Mutational Screening of Transforming Growth Factor Beta2 (TGF-beta 2) Gene in patients with congenital Thrombocytopaenia with Absent Radii (TAR). 122
Un modello in vivo per la valutazione della terapia anti-gene PNA-mediata nel neuroblastoma e altre patologie oncologiche con sovraespressione di N-myc. 118
Inibizione specifica di MYCN mediante PNA-NLS anti gene in cellule di medullobastoma umano:caratterizzazione dellattività anti-tumorale 116
MYCN Drives a Tumor Immunosuppressive Environment Which Impacts Survival in Neuroblastoma 114
Identificazione del primo caso di trisomia 11 e partial tandem duplication del gene MLL in una leucemia acuta mieloide (LAM) MO da paziente Infant 112
valutazione preclinica della terapia epigenetica con inibitori delle iston-deacetilasi ( acido valproico) e dna-metiltransferasi ( decitabina ) in leucemie mieloidi acute con riarrangiamenti di MLL 111
Facial Nerve Graft in Malignant Tumors: The Role of Facial Rehabilitation 110
Expression of T cell receptor alpha gene (TCRA) in human rhabdomyosarcoma and other musculo-skeletal sarcomas. 100
null 95
MLL-AF9 oncogene expression affects cell growth but not terminal differentiation and is downregulated during monocyte-macrophage maturation in AML-M5 THP-1 cells 26
Totale 7.250
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Categoria #
all - tutte 19.045
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 19.045
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021424 0 0 0 0 0 44 9 34 67 32 33 205
2021/2022820 71 26 79 51 74 50 14 51 35 33 173 163
2022/20231.040 112 122 48 106 74 67 60 54 169 36 95 97
2023/2024404 32 49 25 35 26 77 9 29 10 34 28 50
2024/20251.437 57 149 156 100 205 55 154 37 39 122 90 273
2025/20261.372 185 320 269 234 251 113 0 0 0 0 0 0
Totale 7.250