TONELLI, ROBERTO
 Distribuzione geografica
Continente #
NA - Nord America 2.820
EU - Europa 2.693
AS - Asia 2.686
SA - Sud America 137
AF - Africa 131
OC - Oceania 1
Totale 8.468
Nazione #
US - Stati Uniti d'America 2.776
IT - Italia 1.008
CN - Cina 718
SG - Singapore 675
VN - Vietnam 650
GB - Regno Unito 501
DE - Germania 245
HK - Hong Kong 188
SE - Svezia 182
UA - Ucraina 142
FR - Francia 131
IN - India 127
BR - Brasile 101
RU - Federazione Russa 95
NL - Olanda 86
BD - Bangladesh 78
IE - Irlanda 68
KR - Corea 67
CH - Svizzera 63
JP - Giappone 51
FI - Finlandia 40
ZA - Sudafrica 36
CI - Costa d'Avorio 29
SC - Seychelles 28
EE - Estonia 26
CA - Canada 25
TG - Togo 23
PH - Filippine 21
BE - Belgio 20
JO - Giordania 16
PT - Portogallo 16
TH - Thailandia 15
AR - Argentina 14
GR - Grecia 14
PL - Polonia 13
MX - Messico 11
BG - Bulgaria 10
ES - Italia 10
PK - Pakistan 10
AT - Austria 8
ID - Indonesia 8
TW - Taiwan 8
IR - Iran 7
SA - Arabia Saudita 7
UZ - Uzbekistan 7
EC - Ecuador 6
IQ - Iraq 6
TR - Turchia 6
CL - Cile 5
MY - Malesia 5
KZ - Kazakistan 4
NG - Nigeria 4
PE - Perù 4
TN - Tunisia 4
VE - Venezuela 4
AZ - Azerbaigian 3
LT - Lituania 3
RO - Romania 3
BO - Bolivia 2
CZ - Repubblica Ceca 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
HR - Croazia 2
JM - Giamaica 2
MU - Mauritius 2
NO - Norvegia 2
PS - Palestinian Territory 2
AE - Emirati Arabi Uniti 1
AM - Armenia 1
CO - Colombia 1
CY - Cipro 1
FJ - Figi 1
GL - Groenlandia 1
GT - Guatemala 1
HU - Ungheria 1
IL - Israele 1
KE - Kenya 1
LB - Libano 1
MA - Marocco 1
MD - Moldavia 1
MK - Macedonia 1
NP - Nepal 1
PA - Panama 1
SV - El Salvador 1
TZ - Tanzania 1
YE - Yemen 1
Totale 8.468
Città #
Singapore 440
Southend 428
Ashburn 263
Chandler 241
Parma 231
Fairfield 218
Hong Kong 182
Hefei 173
Bologna 152
Santa Clara 151
Dong Ket 141
Woodbridge 135
Seattle 125
Hanoi 124
San Jose 117
Ho Chi Minh City 114
Wilmington 111
Jacksonville 96
Ann Arbor 92
Cambridge 89
Princeton 88
Houston 82
Beijing 80
Dublin 66
Turin 61
Milan 58
Seoul 58
Boardman 55
Bern 53
Lauterbourg 48
Los Angeles 47
Dallas 46
Nanjing 44
Council Bluffs 43
Reggio Emilia 42
Tokyo 42
Padova 39
Westminster 39
Rome 33
Berlin 30
Abidjan 29
Helsinki 29
New York 28
Lomé 23
Haiphong 22
Buffalo 21
Jinan 21
Bengaluru 20
Frankfurt am Main 19
Mülheim 19
Brussels 18
Saint Petersburg 18
San Diego 18
Changsha 17
Redmond 17
Amman 16
Da Nang 15
Des Moines 15
Shenyang 15
Redondo Beach 14
Zhengzhou 13
Hebei 12
Medford 12
Nanchang 12
Phoenix 12
Senago 12
Verona 12
Guangzhou 11
Mahé 11
Mountain View 11
Nuremberg 11
Shanghai 11
São Paulo 11
Tianjin 11
Toronto 11
Warsaw 11
Falkenstein 10
Munich 10
San Giuliano Milanese 10
Sofia 10
Amsterdam 8
Dhaka 8
Florence 8
Hangzhou 8
Hải Dương 8
Jiaxing 8
Ninh Bình 8
Norwalk 8
Taizhou 8
Atlanta 7
Bangkok 7
Brooklyn 7
Kuban 7
London 7
Rimini 7
Rio de Janeiro 7
Taiyuan 7
Turku 7
Can Tho 6
Chicago 6
Totale 5.442
Nome #
Antigene MYCN Silencing by BGA002 Inhibits SCLC Progression Blocking mTOR Pathway and Overcomes Multidrug Resistance 619
The MYCN inhibitor BGA002 restores the retinoic acid response leading to differentiation or apoptosis by the mTOR block in MYCN-amplified neuroblastoma 264
Anti-gene Peptide Nucleic Acid (PNA) specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis. 259
Preclinical Pharmacokinetics in Tumors and Normal Tissues of the Antigene PNA Oligonucleotide MYCN-Inhibitor BGA002 254
A novel MYCN-specific antigene oligonucleotide deregulates mitochondria and inhibits tumor growth in MYCN-amplified neuroblastoma 246
THE P53 REGULATORY GENE MDM2 IS A DIRECT TRANSCRIPTIONAL TARGET OF MYCN IN NEUROBLASTOMA 237
Antitumor Activity of Sustained N-Myc Reduction in Rhabdomyosarcomas and Transcriptional Block by Antigene Therapy 225
p21Waf1/Cip1 is a common target induced by short-chain fatty acid HDAC inhibitors (valproic acid, tributyrin and sodium butyrate) in neuroblastoma cells 215
Chitosan nanoparticles for siRNA delivery: influence of nanoparticle composition on gene silencing efficiency 215
A Peptide Nucleic Acid Embedding a Pseudopeptide Nuclear Localization Sequence in the Backbone Behaves as a Peptide Mimic 196
In vivo bioluminescence imaging of murine xenograft cancer models with a red-shifted thermostable luciferase. 192
MYCN is a novel oncogenic target in pediatric T-cell Acute Lymphoblastic Leukemia 192
Targeted inhibition of NMYC by peptide nucleic acid in N-myc amplified human neuroblastoma cells: cell-cycle inhibition with induction of neuronal cell differentiation and apoptosis 186
MYCN Impact on High-Risk Neuroblastoma: From Diagnosis and Prognosis to Targeted Treatment 182
METHOD FOR SELECTIVE INHIBITION OF HUMAN N-MYC GENE IN N-MYC EXPRESSING TUMORS THROUGH ANTISENSE AND ANTIGEN PEPTIDO-NUCLEIC ACIDS (PNA) 176
The MYCN oncogene as a specific and selective drug target for peripheral and central nervous system tumors. 175
G1 Cell-Cycle Arrest and Apoptosis by Histone Deacetylase Inhibition in MLL-AF9 Acute Myeloid Leukemia Cells Is MLL-AF9 Independent 175
Feasibility and safety of adoptive immunotherapy with ex vivogenerated autologous, cytotoxic T lymphocytes in patients with solid tumor 172
Analisi in vitro ed in vivo dell'attività anti-tumorale dopo inibizione specifica di MYCN mediante PNA-NLS anti-gene nel rabdomiosarcoma umano 172
Expression of BEX1 in acute myeloid leukemia with MLL rearrangements 170
Transient suppression of MLH1 allows effective single-nucleotide substitution by single-stranded DNA oligonucleotides 168
Inibizione specifica di MYCN e MYC mediante PNA-NLS anti-gene in cellule di medulloblastoma umano: caratterizzazione dell'attività anti-tumorale 166
Sulforaphane induces apoptosis in rhabdomyosarcoma and restores TRAIL-sensitivity in the aggressive alveolar subtype leading to tumor elimination in mice. 164
Generation and characterization of bioluminescent xenograft mouse models of MLL-related acute leukemias and in vivo evaluation of luciferase-targeting siRNA nanoparticles 160
Precision Anti-Cancer Medicines by Oligonucleotide Therapeutics in Clinical Research Targeting Undruggable Proteins and Non-Coding RNAs 159
Identification of two MLL-MLLT3 (alias MLL-AF9) chimeric transcripts in the MOLM-13 cell line. 159
FDG small animal PET permits early detection of malignant cells in a xenograft murine model. 158
Trisomy 11 with MLL-PTD in a case of infant AML M0 156
DOWN- REGULATION OF MLL-AF9,MLL,HOXA9,HOXA10, AND MEIS1 EXPRESSION IS NOT OBLIGATORY FOR MONOCYTE- MACROPHAGE MATURATION IN AML -M5 CELL LINES CARRYNG t(9;11)(p22;q23) 154
Mutational Screening of Transforming Growth Factor Beta2 (TGF-beta 2) Gene in patients with congenital Thrombocytopaenia with Absent Radii (TAR). 153
Circular dichroism study of DNA binding by a potential anticancer peptide nucleic acid targeted against the MYCN oncogene. 152
Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma 152
MYCN Drives a Tumor Immunosuppressive Environment Which Impacts Survival in Neuroblastoma 150
G1 cell-cycle arrest and apoptosis by histone deacetylase inhibition in MLL-AF9 acute myeloid leukemia cells is p21 dependent and MLL-AF9 independent 148
Down-regulation of HOXA4, HOXA7, HOXA10, HOXA11 and MEIS1 during monocyte-macrophage differentiation in THP-1 cells 146
Facial Nerve Graft in Malignant Tumors: The Role of Facial Rehabilitation 145
Molecular Imaging of Neuroblastoma Progression in TH-MYCN Transgenic Mice 145
Precoce predittività di attecchimento midollare dopo trapianto allogenico di cellule staminali emopoietiche in pazienti pediatrici mediante valutazione del chimerismo emopoietico con metodo multiplex polymerase chain reaction 143
Growth Inhibition and Proapoptotic Activity Induction by IIF and Valproic Acid on RA-resistant Leukemia Cells. 143
ArgBP2, encoding a negative regulator of ABL, is fused to MLL in a case of infant M5 acute myeloid leukemia involving 4q35 and 11q23. 143
Un modello in vivo per la valutazione della terapia anti-gene PNA-mediata nel neuroblastoma e altre patologie oncologiche con sovraespressione di N-myc. 143
Inibizione specifica di MYCN mediante PNA-NLS anti gene in cellule di medullobastoma umano:caratterizzazione dellattività anti-tumorale 140
EX VIVO GENERATION AND EXPANSION OF ANTI-TUMOR CYTOTOXIC T-CELL LINES DERIVED FROM PATIENTS OR THEIR HLA-IDENTICAL SIBLING 135
valutazione preclinica della terapia epigenetica con inibitori delle iston-deacetilasi ( acido valproico) e dna-metiltransferasi ( decitabina ) in leucemie mieloidi acute con riarrangiamenti di MLL 128
Identificazione del primo caso di trisomia 11 e partial tandem duplication del gene MLL in una leucemia acuta mieloide (LAM) MO da paziente Infant 128
Expression of T cell receptor alpha gene (TCRA) in human rhabdomyosarcoma and other musculo-skeletal sarcomas. 121
null 95
Idiopathic Pulmonary Fibrosis: Analysis of Predisposing Variants in Patients with Familial Forms 67
MLL-AF9 oncogene expression affects cell growth but not terminal differentiation and is downregulated during monocyte-macrophage maturation in AML-M5 THP-1 cells 44
Totale 8.587
Categoria #
all - tutte 22.039
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 22.039


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021205 0 0 0 0 0 0 0 0 0 0 0 205
2021/2022820 71 26 79 51 74 50 14 51 35 33 173 163
2022/20231.040 112 122 48 106 74 67 60 54 169 36 95 97
2023/2024404 32 49 25 35 26 77 9 29 10 34 28 50
2024/20251.437 57 149 156 100 205 55 154 37 39 122 90 273
2025/20262.709 185 320 269 234 251 140 210 84 534 182 169 131
Totale 8.587