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TONELLI, ROBERTO

TONELLI, ROBERTO  

DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE  

Ricercatori  

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Risultati 1 - 20 di 45 (tempo di esecuzione: 0.05 secondi).
Titolo Autore(i) Anno Periodico Editore Tipo File
Preclinical Pharmacokinetics in Tumors and Normal Tissues of the Antigene PNA Oligonucleotide MYCN-Inhibitor BGA002 Scardovi, Anna Lisa; Bartolucci, Damiano; Montemurro, Luca; Bortolotti, Sonia; Angelucci, Silvia;... Amadesi, Camilla; Nieddu, Giammario; Oosterholt, Sean; Cerisoli, Lucia; Della Pasqua, Oscar; Hrelia, Patrizia; Tonelli, Roberto 2024-01-01 NUCLEIC ACID THERAPEUTICS - 1.01 Articolo in rivista Supplementary Material Scardovi et al NAT 2024.pdf; MTNA-S-23-01104_bis.pdf
Antigene MYCN Silencing by BGA002 Inhibits SCLC Progression Blocking mTOR Pathway and Overcomes Multidrug Resistance Bortolotti, Sonia; Angelucci, Silvia; Montemurro, Luca; Bartolucci, Damiano; Raieli, Salvatore; L...ampis, Silvia; Amadesi, Camilla; Scardovi, Annalisa; Nieddu, Giammario; Cerisoli, Lucia; Paganelli, Francesca; Chiarini, Francesca; Teti, Gabriella; Falconi, Mirella; Pession, Andrea; Hrelia, Patrizia; Tonelli, Roberto 2023-01-01 CANCERS - 1.01 Articolo in rivista cancers-15-00990.pdf
MYCN Impact on High-Risk Neuroblastoma: From Diagnosis and Prognosis to Targeted Treatment Bartolucci D.; Montemurro L.; Raieli S.; Lampis S.; Pession A.; Hrelia P.; Tonelli R. 2022-01-01 CANCERS - 1.01 Articolo in rivista cancers-14-04421.pdf
Precision Anti-Cancer Medicines by Oligonucleotide Therapeutics in Clinical Research Targeting Undruggable Proteins and Non-Coding RNAs Bartolucci D.; Pession A.; Hrelia P.; Tonelli R. 2022-01-01 PHARMACEUTICS - 1.01 Articolo in rivista Bartolucci D, et al Pharmaceutics-14-01453.pdf
The MYCN inhibitor BGA002 restores the retinoic acid response leading to differentiation or apoptosis by the mTOR block in MYCN-amplified neuroblastoma Lampis S.; Raieli S.; Montemurro L.; Bartolucci D.; Amadesi C.; Bortolotti S.; Angelucci S.; Scar...dovi A.L.; Nieddu G.; Cerisoli L.; Paganelli F.; Valente S.; Fischer M.; Martelli A.M.; Pasquinelli G.; Pession A.; Hrelia P.; Tonelli R. 2022-01-01 JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH - 1.01 Articolo in rivista Lampis_et_al-2022-Journal_of_Experimental_&_Clinical_Cancer_Research.pdf; 19688410.zip
MYCN Drives a Tumor Immunosuppressive Environment Which Impacts Survival in Neuroblastoma Raieli S.; Di Renzo D.; Lampis S.; Amadesi C.; Montemurro L.; Pession A.; Hrelia P.; Fischer M.; ...Tonelli R. 2021-01-01 FRONTIERS IN ONCOLOGY - 1.01 Articolo in rivista Frontiers in Oncology 25 February 2021.pdf; file supplemenatari.zip
Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma Moreno L.; Barone G.; DuBois S.G.; Molenaar J.; Fischer M.; Schulte J.; Eggert A.; Schleiermacher... G.; Speleman F.; Chesler L.; Geoerger B.; Hogarty M.D.; Irwin M.S.; Bird N.; Blanchard G.B.; Buckland S.; Caron H.; Davis S.; De Wilde B.; Deubzer H.E.; Dolman E.; Eilers M.; George R.E.; George S.; Jaroslav; Maris J.M.; Marshall L.; Merchant M.; Mortimer P.; Owens C.; Philpott A.; Poon E.; Shay J.W.; Tonelli R.; Valteau-Couanet D.; Vassal G.; Park J.R.; Pearson A.D.J. 2020-01-01 EUROPEAN JOURNAL OF CANCER - 1.01 Articolo in rivista -
A novel MYCN-specific antigene oligonucleotide deregulates mitochondria and inhibits tumor growth in MYCN-amplified neuroblastoma Montemurro L.; Raieli S.; Angelucci S.; Bartolucci D.; Amadesi C.; Lampis S.; Scardovi A.L.; Vent...urelli L.; Nieddu G.; Cerisoli L.; Fischer M.; Teti G.; Falconi M.; Pession A.; Hrelia P.; Tonelli R. 2019-01-01 CANCER RESEARCH - 1.01 Articolo in rivista montemurro2019.pdf
MYCN is a novel oncogenic target in pediatric T-cell Acute Lymphoblastic Leukemia A. Astolfi; F. Vendemini; M. Urbini; F. Melchionda; R. Masetti; M. Franzoni; V. Libri; S. Serrava...lle; M. Togni; L. Montemurro; R. Rondelli; G. Paone; D. Bressanin; F. Chiarini; A.M. Martelli; R. Tonelli; A. Pession. 2014-01-01 ONCOTARGET - 1.01 Articolo in rivista -
Sulforaphane induces apoptosis in rhabdomyosarcoma and restores TRAIL-sensitivity in the aggressive alveolar subtype leading to tumor elimination in mice. Bergantin E; Quarta C; Nanni C; Fanti S; Pession A; Cantelli-Forti G; Tonelli R; Hrelia P 2014-01-01 CANCER BIOLOGY & THERAPY - 1.01 Articolo in rivista -
Molecular Imaging of Neuroblastoma Progression in TH-MYCN Transgenic Mice Carmelo Quarta; Erika Cantelli; Cristina Nanni; Valentina Ambrosini; Daniela D’ambrosio; Korinne ...Di Leo; Silvia Angelucci; Federico Zagni; Filippo Lodi; Mario Marengo; William A. Weiss; Andrea Pession; Roberto Tonelli; Stefano Fanti 2013-01-01 MOLECULAR IMAGING AND BIOLOGY - 1.01 Articolo in rivista -
Antitumor Activity of Sustained N-Myc Reduction in Rhabdomyosarcomas and Transcriptional Block by Antigene Therapy R. Tonelli; A. McIntyre; C. Camerin; Z.S. Walters; K. Di Leo; J. Selfe; S. Purgato; E. Missiaglia...; A. Tortori; J. Renshaw; A. Astolfi; K.R. Taylor; S. Serravalle; R. Bishop; C. Nanni; L.J. Valentijn; A. Faccini; I. Leuschner; S. Formica; Jorge S Reis-Filho9; V. Ambrosini; K. Thway; M. Franzoni; B. Summersgill; R. Marchelli; P. Hrelia; G. Cantelli-Forti; S. Fanti; R. Corradini; A. Pession; J. Shipley 2012-01-01 CLINICAL CANCER RESEARCH - 1.01 Articolo in rivista -
Feasibility and safety of adoptive immunotherapy with ex vivogenerated autologous, cytotoxic T lymphocytes in patients with solid tumor D MONTAGNA; I TURIN; R SCHIAVO; E MONTINI;
N ZAFFARONI; R VILLA; S SECONDINO;
I SCHIAVETTO; L CAL...IOGNA; F LOCATELLI;
VIRGINIA LIBRI; ANDREA PESSION; R TONELLI; R MACCARIO;
S SIENA; P PEDRAZZOLI 		2012-01-01 CYTOTHERAPY - 1.01 Articolo in rivista -
Generation and characterization of bioluminescent xenograft mouse models of MLL-related acute leukemias and in vivo evaluation of luciferase-targeting siRNA nanoparticles FAZZINA R.; LOMBARDINI L.; MEZZANOTTE L.; RODA A.; HRELIA P; PESSION A.; TONELLI R. 2012-01-01 INTERNATIONAL JOURNAL OF ONCOLOGY - 1.01 Articolo in rivista -
Transient suppression of MLH1 allows effective single-nucleotide substitution by single-stranded DNA oligonucleotides M. Dekker; S. de Vries; M. Aarts; R. Dekker; C Brouwersa;
O. Wiebenga; N. de Wind; E. Cantelli; R.... Tonelli; H te Riele 		2011-01-01 MUTATION RESEARCH - 1.01 Articolo in rivista -
A Peptide Nucleic Acid Embedding a Pseudopeptide Nuclear Localization Sequence in the Backbone Behaves as a Peptide Mimic Sforza S.; Tedeschi T.; Calabretta A.; Corradini R.; Camerin C.; Tonelli R.; Pession A.; Marchell...i R. 2010-01-01 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY - 1.01 Articolo in rivista -
Chitosan nanoparticles for siRNA delivery: influence of nanoparticle composition on gene silencing efficiency R. Tonelli; B. Luppi; L. Lombardini; S. Rampelli; P. Hrelia; A. Pession 2010-01-01 - s.n 4.02 Riassunto (Abstract) -
In vivo bioluminescence imaging of murine xenograft cancer models with a red-shifted thermostable luciferase. Mezzanotte L; Fazzina R; Michelini E; Tonelli R; Pession A; Branchini B; Roda A 2010-01-01 MOLECULAR IMAGING AND BIOLOGY - 1.01 Articolo in rivista -
Down-regulation of HOXA4, HOXA7, HOXA10, HOXA11 and MEIS1 during monocyte-macrophage differentiation in THP-1 cells V MARTINO; A BIANCHERA; L REIA; O BUSSOLATI;
R FAZZINA; F MARINO; L MONTEMURRO; R TONELLI;
A PESS...ION; GC GAZZOLA; R SALA 		2009-01-01 MOLECULAR MEDICINE REPORTS - 1.01 Articolo in rivista -
Circular dichroism study of DNA binding by a potential anticancer peptide nucleic acid targeted against the MYCN oncogene. Faccini A; Tortori A; Tedeschi T; Sforza S; Tonelli R; Pession A; Corradini R; Marchelli R. 2008-01-01 CHIRALITY - 1.01 Articolo in rivista -