Sfoglia per Autore
Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents.
2008 Radi M; Crespan E; Botta G; Falchi F; Maga G; Manetti F; Corradi V; Mancini M; Santucci MA; Schenone S; Botta M.
Pharmacophore modeling and molecular docking led to the discovery of inhibitors of human immunodeficiency virus-1 replication targeting the human cellular aspartic acid-glutamic acid-alanine-aspartic acid box polypeptide 3
2008 Maga G.; Falchi F.; Garbelli A.; Belfiore A.; Witvrouw M.; Manetti F.; Botta M.
N-(thiazol-2-yl)-2-thiophene carboxamide derivatives as Abl inhibitors identified by a pharmacophore-based database screening of commercially available compounds
2008 Manetti F.; Falchi F.; Crespan E.; Schenone S.; Maga G.; Botta M.
3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors
2009 Falchi F.; Manetti F.; Carraro F.; Naldini A.; Maga G.; Crespan E.; Schenone S.; Bruno O.; Brullo C.; Botta M.
Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data
2009 Dreassi E.; Zizzari A.T.; Falchi F.; Schenone S.; Santucci A.; Maga G.; Botta M.
Design and synthesis of thiadiazoles and thiazoles targeting the Bcr-Abl T315I mutant: From docking false positives to ATP-noncompetitive inhibitors
2010 Radi M.; Crespan E.; Falchi F.; Bernardo V.; Zanoli S.; Manetti F.; Schenone S.; Maga G.; Botta M.
Inhibitors of human immunodeficiency virus-1 replication targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase
2010 Giovanni Maga, Federico Falchi, Anna Garbelli, Marco Radi, Stefania Paolucci, Fausto Baldanti, Maurizio Botta
N-[2-methyl-5-(triazol-1-yl)phenyl]pyrimidin-2-amine as a Scaffold for the synthesis of inhibitors of Bcr-Abl
2011 Arioli F.; Borrelli S.; Colombo F.; Falchi F.; Filippi I.; Crespan E.; Naldini A.; Scalia G.; Silvani A.; Maga G.; Carraro F.; Botta M.; Passarella D.
COMPOUNDS WITH DDX3 INHIBITORY ACTIVITY AND USES THEREOF
2011 RADI MARCO; BOTTA MAURIZIO; FALCHI FEDERICO; MAGA GIOVANNI; BALDANTI FAUSTO; PAOLUCCI STEFANIA
Toward the Discovery of Novel Anti-HIV Drugs. Second-Generation Inhibitors of the Cellular ATPase DDX3 with Improved Anti-HIV Activity: Synthesis, Structure-Activity Relationship Analysis, Cytotoxicity Studies, and Target Validation
2011 Maga G.; Falchi F.; Radi M.; Botta L.; Casaluce G.; Bernardini M.; Irannejad H.; Manetti F.; Garbelli A.; Samuele A.; Zanoli S.; Este J.A.; Gonzalez E.; Zucca E.; Paolucci S.; Baldanti F.; DeRijck J.; Debyser Z.; Botta M.
NON PEPTIDIC 14-3-3 INHIBITORS AND THE USE THEREOF
2011 BOTTA MAURIZIO; CORRADI VALENTINA; FALCHI FEDERICO; MANCINI EMANUELA; SANTUCCI MARIA ALESSANDRA
Targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase as a novel strategy to inhibit viral replication
2011 Garbelli A.; Radi M.; Falchi F.; Beermann S.; Zanoli S.; Manetti F.; Dietrich U.; Botta M.; Maga G.
Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case
2011 Corradi V; Mancini M; Santucci MA; Carlomagno T; Sanfelice D; Mori M; Vignaroli G; Falchi F; Manetti F; Radi M; Botta M
Fyn kinase in brain diseases and cancer: The search for inhibitors
2011 Schenone S.; Brullo C.; Musumeci F.; Biava M.; Falchi F.; Botta M.
A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin formulation
2012 Radi M.; Evensen L.; Dreassi E.; Zamperini C.; Caporicci M.; Falchi F.; Musumeci F.; Schenone S.; Lorens J.B.; Botta M.
Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors
2012 Radi M.; Falchi F.; Garbelli A.; Samuele A.; Bernardo V.; Paolucci S.; Baldanti F.; Schenone S.; Manetti F.; Maga G.; Botta M.
Next generation of antiretroviral agents targeting the RNA binding site of the HIV-1 cellular cofactor DDX3: an innovative therapeutic approach
2012 Giovanni Maga, Anna Garbelli, Marco Radi, Federico Falchi, Alberta Samuele, Stefania Paolucci, Fausto Baldanti, Fabrizio Manetti, Sandra Beermann, Ursula Dietrich, Maurizio Botta
Identification of Hck Inhibitors As Hits for the Development of Antileukemia and Anti-HIV Agents
2013 Tintori C.; Laurenzana I.; LaRocca F.; Falchi F.; Carraro F.; Ruiz A.; Este J.A.; Kissova M.; Crespan E.; Maga G.; Biava M.; Brullo C.; Schenone S.; Botta M.
Collecting and assessing human lactate dehydrogenase-A conformations for structure-based virtual screening
2013 R. Buonfiglio; M. Ferraro; F. Falchi; A. Cavalli; M. Masetti; M. Recanatini
Protein Dynamics of the HIF-2α PAS-B Domain upon Heterodimerization and Ligand Binding
2014 Matteo Masetti;Federico Falchi;Maurizio Recanatini
Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
---|---|---|---|---|---|---|
Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents. | Radi M; Crespan E; Botta G; Falchi F; Maga G; Manetti F; Corradi V; Mancini M; Santucci MA; Schen...one S; Botta M. | 2008-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
Pharmacophore modeling and molecular docking led to the discovery of inhibitors of human immunodeficiency virus-1 replication targeting the human cellular aspartic acid-glutamic acid-alanine-aspartic acid box polypeptide 3 | Maga G.; Falchi F.; Garbelli A.; Belfiore A.; Witvrouw M.; Manetti F.; Botta M. | 2008-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
N-(thiazol-2-yl)-2-thiophene carboxamide derivatives as Abl inhibitors identified by a pharmacophore-based database screening of commercially available compounds | Manetti F.; Falchi F.; Crespan E.; Schenone S.; Maga G.; Botta M. | 2008-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors | Falchi F.; Manetti F.; Carraro F.; Naldini A.; Maga G.; Crespan E.; Schenone S.; Bruno O.; Brullo... C.; Botta M. | 2009-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data | Dreassi E.; Zizzari A.T.; Falchi F.; Schenone S.; Santucci A.; Maga G.; Botta M. | 2009-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Design and synthesis of thiadiazoles and thiazoles targeting the Bcr-Abl T315I mutant: From docking false positives to ATP-noncompetitive inhibitors | Radi M.; Crespan E.; Falchi F.; Bernardo V.; Zanoli S.; Manetti F.; Schenone S.; Maga G.; Botta M. | 2010-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
Inhibitors of human immunodeficiency virus-1 replication targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase | Giovanni Maga, Federico Falchi, Anna Garbelli, Marco Radi, Stefania Paolucci, Fausto Baldanti, Ma...urizio Botta | 2010-01-01 | RETROVIROLOGY | - | 1.01 Articolo in rivista | - |
N-[2-methyl-5-(triazol-1-yl)phenyl]pyrimidin-2-amine as a Scaffold for the synthesis of inhibitors of Bcr-Abl | Arioli F.; Borrelli S.; Colombo F.; Falchi F.; Filippi I.; Crespan E.; Naldini A.; Scalia G.; Sil...vani A.; Maga G.; Carraro F.; Botta M.; Passarella D. | 2011-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
COMPOUNDS WITH DDX3 INHIBITORY ACTIVITY AND USES THEREOF | RADI MARCO; BOTTA MAURIZIO; FALCHI FEDERICO; MAGA GIOVANNI; BALDANTI FAUSTO; PAOLUCCI STEFANIA | 2011-01-01 | - | - | 6.01 Brevetto | - |
Toward the Discovery of Novel Anti-HIV Drugs. Second-Generation Inhibitors of the Cellular ATPase DDX3 with Improved Anti-HIV Activity: Synthesis, Structure-Activity Relationship Analysis, Cytotoxicity Studies, and Target Validation | Maga G.; Falchi F.; Radi M.; Botta L.; Casaluce G.; Bernardini M.; Irannejad H.; Manetti F.; Garb...elli A.; Samuele A.; Zanoli S.; Este J.A.; Gonzalez E.; Zucca E.; Paolucci S.; Baldanti F.; DeRijck J.; Debyser Z.; Botta M. | 2011-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
NON PEPTIDIC 14-3-3 INHIBITORS AND THE USE THEREOF | BOTTA MAURIZIO; CORRADI VALENTINA; FALCHI FEDERICO; MANCINI EMANUELA; SANTUCCI MARIA ALESSANDRA | 2011-01-01 | - | - | 6.01 Brevetto | - |
Targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase as a novel strategy to inhibit viral replication | Garbelli A.; Radi M.; Falchi F.; Beermann S.; Zanoli S.; Manetti F.; Dietrich U.; Botta M.; Maga G. | 2011-01-01 | CURRENT MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case | Corradi V; Mancini M; Santucci MA; Carlomagno T; Sanfelice D; Mori M; Vignaroli G; Falchi F; Mane...tti F; Radi M; Botta M | 2011-01-01 | BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
Fyn kinase in brain diseases and cancer: The search for inhibitors | Schenone S.; Brullo C.; Musumeci F.; Biava M.; Falchi F.; Botta M. | 2011-01-01 | CURRENT MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin formulation | Radi M.; Evensen L.; Dreassi E.; Zamperini C.; Caporicci M.; Falchi F.; Musumeci F.; Schenone S.;... Lorens J.B.; Botta M. | 2012-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors | Radi M.; Falchi F.; Garbelli A.; Samuele A.; Bernardo V.; Paolucci S.; Baldanti F.; Schenone S.; ...Manetti F.; Maga G.; Botta M. | 2012-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
Next generation of antiretroviral agents targeting the RNA binding site of the HIV-1 cellular cofactor DDX3: an innovative therapeutic approach | Giovanni Maga, Anna Garbelli, Marco Radi, Federico Falchi, Alberta Samuele, Stefania Paolucci, Fa...usto Baldanti, Fabrizio Manetti, Sandra Beermann, Ursula Dietrich, Maurizio Botta | 2012-01-01 | RETROVIROLOGY | - | 1.01 Articolo in rivista | - |
Identification of Hck Inhibitors As Hits for the Development of Antileukemia and Anti-HIV Agents | Tintori C.; Laurenzana I.; LaRocca F.; Falchi F.; Carraro F.; Ruiz A.; Este J.A.; Kissova M.; Cre...span E.; Maga G.; Biava M.; Brullo C.; Schenone S.; Botta M. | 2013-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
Collecting and assessing human lactate dehydrogenase-A conformations for structure-based virtual screening | R. Buonfiglio; M. Ferraro; F. Falchi; A. Cavalli; M. Masetti; M. Recanatini | 2013-01-01 | JOURNAL OF CHEMICAL INFORMATION AND MODELING | - | 1.01 Articolo in rivista | - |
Protein Dynamics of the HIF-2α PAS-B Domain upon Heterodimerization and Ligand Binding | Matteo Masetti;Federico Falchi;Maurizio Recanatini | 2014-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | 2014_masetti.pdf |
Legenda icone
- file ad accesso aperto
- file disponibili sulla rete interna
- file disponibili agli utenti autorizzati
- file disponibili solo agli amministratori
- file sotto embargo
- nessun file disponibile