On-line in situ monitoring of radiation emitted by radiotracers during intravenous injection is of crucial importance for the safety of patients and personnel involved in nuclear medicine treatments and analysis. The aim of this work is to assess wearable perovskite ionizing radiation detectors for such application. With this purpose pixelated direct detector based on thin films of 2D layered perovskite PEA2PbBr4 are tested for the monitoring of gamma-rays emitted by 18F radiopharmaceutical under different experimental conditions. The wearable detector is here demonstrated being able to detect in real-time the gamma-rays emitted by annihilation of 18F radiotracer. Its reliability is assessed by 18F half-life measurement with a maximum accuracy deviation within 8%. The detector also successes in its validation for the foreseen application, demonstrating able to monitor in real-time the whole injection process and extravasation event.
Basiricò, L., Verdi, M., Ciavatti, A., Piergallini, L., Grassi, E., Fioroni, F., et al. (2024). Wearable Perovskite Films for On‐Line Monitoring of Radiotracers in Nuclear Medicine. ADVANCED MATERIALS TECHNOLOGIES, 2401111, 1-9 [10.1002/admt.202401111].
Wearable Perovskite Films for On‐Line Monitoring of Radiotracers in Nuclear Medicine
Basiricò, Laura
;Verdi, Matteo;Ciavatti, Andrea
;Grassi, Elisa;Margotti, Lorenzo;Fraboni, Beatrice
2024
Abstract
On-line in situ monitoring of radiation emitted by radiotracers during intravenous injection is of crucial importance for the safety of patients and personnel involved in nuclear medicine treatments and analysis. The aim of this work is to assess wearable perovskite ionizing radiation detectors for such application. With this purpose pixelated direct detector based on thin films of 2D layered perovskite PEA2PbBr4 are tested for the monitoring of gamma-rays emitted by 18F radiopharmaceutical under different experimental conditions. The wearable detector is here demonstrated being able to detect in real-time the gamma-rays emitted by annihilation of 18F radiotracer. Its reliability is assessed by 18F half-life measurement with a maximum accuracy deviation within 8%. The detector also successes in its validation for the foreseen application, demonstrating able to monitor in real-time the whole injection process and extravasation event.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.