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EnglishPost-weaning multisystemic wasting syndrome (PMWS) is causally associated with infection of pigs by Porcine Circovirus type 2 (PCV2). Lesions in lymphoid tissues of 52 PMWS-positive pigs sampled years 1998-2000 (epidemic) were compared with lesions from 127 PMWS-positive pigs sampled 2006-2008 (endemic). A variable degree of lymphoid depletion was a constant feature in tissues with microgranulomas formed by a scant number of centrofollicular epithelioid cells, or granulomas clustered in multiple undelimited nodules with little tendency to confluence, formed by epithelioid macrophages and a few multinucleate giant cells. Granulomatosis of lymphoid tissues is known in PMWS of pigs due to type IV hypersensitivity. Granulomatosis of lymphoid tissues was apparent in 1.07% during the 1998-2000 period and in 12.42% in the more recent period. Results suggest that frequency of lymphoid granulomatosis is influenced by the epidemiology of the disease.
| Titolo: | Granulomatosis of lymphoid tissue in post-weaning multisystemic wasting syndrome in pigs during epidemic and endemic phases. |
| Autore/i: | FUSARO, LAURA; SARLI, GIUSEPPE; MORANDI, FEDERICO; BACCI, BARBARA; OSTANELLO, FABIO; G. Leotti; MANDRIOLI, LUCIANA; MARCATO, PAOLO STEFANO |
| Autore/i Unibo: | |
| Anno: | 2010 |
| Rivista: | |
| Abstract: | Post-weaning multisystemic wasting syndrome (PMWS) is causally associated with infection of pigs by Porcine Circovirus type 2 (PCV2). Lesions in lymphoid tissues of 52 PMWS-positive pigs sampled years 1998-2000 (epidemic) were compared with lesions from 127 PMWS-positive pigs sampled 2006-2008 (endemic). A variable degree of lymphoid depletion was a constant feature in tissues with microgranulomas formed by a scant number of centrofollicular epithelioid cells, or granulomas clustered in multiple undelimited nodules with little tendency to confluence, formed by epithelioid macrophages and a few multinucleate giant cells. Granulomatosis of lymphoid tissues is known in PMWS of pigs due to type IV hypersensitivity. Granulomatosis of lymphoid tissues was apparent in 1.07% during the 1998-2000 period and in 12.42% in the more recent period. Results suggest that frequency of lymphoid granulomatosis is influenced by the epidemiology of the disease. |
| Data prodotto definitivo in UGOV: | 2010-12-07 16:35:42 |
| Appare nelle tipologie: | 1.01 Articolo in rivista |
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