The use of aziridine carboxylates as intermediates in the synthesis of optically active compounds is a subject of current interest. The ring-opening of aziridine, consequence of ring strain, is the most important feature of their chemistry and serves as the basis of the synthesis of substituted a- and /3-amino acids, which is a topic of interest in our laboratory.
Cardillo G., Casolari S., Gentilucci L., Tomasini C. (1996). Asymmetric Synthesis of AIkyl Aziridine-2-Carboxylates from Chiral 3'-Benzyloxy-aminoimides. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION IN ENGLISH, 35(16), 1848-1849 [10.1002/anie.199618481].
Asymmetric Synthesis of AIkyl Aziridine-2-Carboxylates from Chiral 3'-Benzyloxy-aminoimides
Casolari S.Investigation
;Gentilucci L.Investigation
;Tomasini C.Investigation
1996
Abstract
The use of aziridine carboxylates as intermediates in the synthesis of optically active compounds is a subject of current interest. The ring-opening of aziridine, consequence of ring strain, is the most important feature of their chemistry and serves as the basis of the synthesis of substituted a- and /3-amino acids, which is a topic of interest in our laboratory.File in questo prodotto:
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