A series of 4-heterotricyclic substituted 1,4-dihydropyridines were prepared. The compounds were evaluated for inotropic, chronotropic and calcium antagonist properties. The tested compounds are fairly good as calcium antagonists, but exert potent selective bradycardic effects.
Rampa A., Chiarini A., Bisi A., Budriesi R., Valenti P. (1991). 4-Heterotricyclic substituted 1,4-dihydropyridines with a potent selective bradycardic effect. ARZNEIMITTEL-FORSCHUNG, 41(7), 705-709.
4-Heterotricyclic substituted 1,4-dihydropyridines with a potent selective bradycardic effect
Rampa A.;Chiarini A.;Bisi A.;Budriesi R.;Valenti P.
1991
Abstract
A series of 4-heterotricyclic substituted 1,4-dihydropyridines were prepared. The compounds were evaluated for inotropic, chronotropic and calcium antagonist properties. The tested compounds are fairly good as calcium antagonists, but exert potent selective bradycardic effects.File in questo prodotto:
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