A series of 4-heterotricyclic substituted 1,4-dihydropyridines were prepared. The compounds were evaluated for inotropic, chronotropic and calcium antagonist properties. The tested compounds are fairly good as calcium antagonists, but exert potent selective bradycardic effects.

4-Heterotricyclic substituted 1,4-dihydropyridines with a potent selective bradycardic effect

Rampa A.;Chiarini A.;Bisi A.;Budriesi R.;Valenti P.
1991

Abstract

A series of 4-heterotricyclic substituted 1,4-dihydropyridines were prepared. The compounds were evaluated for inotropic, chronotropic and calcium antagonist properties. The tested compounds are fairly good as calcium antagonists, but exert potent selective bradycardic effects.
1991
Rampa A.; Chiarini A.; Bisi A.; Budriesi R.; Valenti P.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/911632
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