Tendons and ligaments (T/L) are connective tissues with complex multiscale structure and mechanical properties [1]. Electrospinning can replicate T/L from the fibrillar-level up to the whole tissue [2]. Nylon6,6 (NY) and polyurethane (PU) are suitable polymers for T/L tissue replacement [3, 4]. In this study, we produced electrospun NY fascicle-inspired bundles, grouping them with electrospun membranes of NY or PU (reproducing the ones covering the natural tissue) in different T/L levels of hierarchical complexity. The study aimed to identify the relationship between the structure and mechanics of these devices when the hierarchical complexity was increased and the materials of membranes were changed.

Multiscale Performances of Hierarchical Electrospun Biostable Devices for Tendon and Ligament Replacement / Alberto Sensini, Carlo Gotti, Chiara Gualandi, Maria Vittoria Ricioppo, Gregorio Marchiori, Nicola Sancisi, Milena Fini, Maria Letizia Focarete, Luca Cristofolini, Andrea Zucchelli. - ELETTRONICO. - (2022), pp. 1-1. (Intervento presentato al convegno ToScA 2022 tenutosi a Queen Mary University London nel 7-9 September 2022).

Multiscale Performances of Hierarchical Electrospun Biostable Devices for Tendon and Ligament Replacement

Carlo Gotti;Chiara Gualandi;Nicola Sancisi;Maria Letizia Focarete;Luca Cristofolini;Andrea Zucchelli
2022

Abstract

Tendons and ligaments (T/L) are connective tissues with complex multiscale structure and mechanical properties [1]. Electrospinning can replicate T/L from the fibrillar-level up to the whole tissue [2]. Nylon6,6 (NY) and polyurethane (PU) are suitable polymers for T/L tissue replacement [3, 4]. In this study, we produced electrospun NY fascicle-inspired bundles, grouping them with electrospun membranes of NY or PU (reproducing the ones covering the natural tissue) in different T/L levels of hierarchical complexity. The study aimed to identify the relationship between the structure and mechanics of these devices when the hierarchical complexity was increased and the materials of membranes were changed.
2022
Proceedings of ToScA 2022
1
1
Multiscale Performances of Hierarchical Electrospun Biostable Devices for Tendon and Ligament Replacement / Alberto Sensini, Carlo Gotti, Chiara Gualandi, Maria Vittoria Ricioppo, Gregorio Marchiori, Nicola Sancisi, Milena Fini, Maria Letizia Focarete, Luca Cristofolini, Andrea Zucchelli. - ELETTRONICO. - (2022), pp. 1-1. (Intervento presentato al convegno ToScA 2022 tenutosi a Queen Mary University London nel 7-9 September 2022).
Alberto Sensini, Carlo Gotti, Chiara Gualandi, Maria Vittoria Ricioppo, Gregorio Marchiori, Nicola Sancisi, Milena Fini, Maria Letizia Focarete, Luca Cristofolini, Andrea Zucchelli
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/905971
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