We describe 2 patients with associated central and peripheral demyelination. Electrophysiological studies revealed a demyelinating polyneuropathy with sensory and motor conduction blocks. Visual evoked potentials were abnormal. Motor evoked potentials showed abnormal central conduction time in 1 patient. Magnetic resonance imaging revealed regions of abnormal high signal in the spinal cord and brain; sural nerve biopsy disclosed a demyelinating neuropathy. Both patients showed clinical and electrophysiological improvement after steroid therapy.
Steroid-responsive multifocal demyelinating neuropathy with central involvement / Liguori R.; Rizzi R.; Vetrugno R.; Salvi F.; Lugaresi A.; Cevoli S.; Montagna P.. - In: MUSCLE & NERVE. - ISSN 0148-639X. - STAMPA. - 22:2(1999), pp. 262-265. [10.1002/(SICI)1097-4598(199902)22:2<262::AID-MUS16>3.0.CO;2-1]
Steroid-responsive multifocal demyelinating neuropathy with central involvement
Liguori R.;Vetrugno R.;Lugaresi A.;Cevoli S.;Montagna P.
1999
Abstract
We describe 2 patients with associated central and peripheral demyelination. Electrophysiological studies revealed a demyelinating polyneuropathy with sensory and motor conduction blocks. Visual evoked potentials were abnormal. Motor evoked potentials showed abnormal central conduction time in 1 patient. Magnetic resonance imaging revealed regions of abnormal high signal in the spinal cord and brain; sural nerve biopsy disclosed a demyelinating neuropathy. Both patients showed clinical and electrophysiological improvement after steroid therapy.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
