Peptide Drug Discovery and Process Development Perspectives

The peptide market will show incredible performances growing from the actual 30 B$ to the 58 B$ by the year 2026. This jump is directly related to the improvement of the drug design and development process achieved during the last 10 years (1). In fact, not long time ago, once the active peptide was identified, the drug, a peptidomimetic molecule, was obtained after an extensive medicinal chemistry program. Nowadays, with a few modifications of the natural sequence, it is possible to generate analogue peptides with a controlled conformation and an improved pharmaceutical profile, like long halflife and oral delivery.