In a full factorial design (4 diets X challenge, Yes/No), 72 weaning pigs were assigned to one of the diets: Control; experimental diets, obtained with the addition of 2 g/kg free sodium butyrate (fNaB), or 0.6 g/kg fat-protected sodium butyrate (pNaB), or 2 g/kg INVE-NutriAd commercial mixture (Mix, based on 75 g/kg protected butyrate). Oral challenge with Escherichia coli K88 was done on 2/3 of pigs on d 7. Pigs were slaughtered on d 13. The mortality in challenged pigs, tended to be higher in control group (50.0 %) than in the three supplemented groups (23.5%). Growth tended to be increased averagely by the supplements (P = 0.100) after the challenge, that also significantly reduced growth. In general the diet did not affect the fecal shedding of Escherichia coli and Lactobacilli, the K88-specific IgA activity in blood, the morphology of oxyntic mucosa and the expression of H+/K+-ATPase gene. The supplementations tended to increase villous length of jejunum (P = 0.101). On the whole, growth, villous height and surviving rate can be positively affected either when the supplementation is done by free butyrate, by protected butyrate or by the special Inve Nutri-Ad product and these effects are distributed both on pigs infected or not with Escherichia coli K88.
Effect of different butyrate supplementations on growth and health of weaning pigs challenged or not with E. coli K88 / Bosi P; Messori S; Nisi I; Russo D; Casini L; Coloretti F; Schwarzer K; Trevisi P. - In: ITALIAN JOURNAL OF ANIMAL SCIENCE. - ISSN 1594-4077. - STAMPA. - 8 (suppl.2):(2009), pp. 268-270. (Intervento presentato al convegno PROCEEDINGS OF THE ASPA 18TH CONGRESS tenutosi a PALERMO nel JUNE 9-12, 2009).
Effect of different butyrate supplementations on growth and health of weaning pigs challenged or not with E. coli K88
BOSI, PAOLO;MESSORI, STEFANO;RUSSO, DOMENICO;CASINI, LUISA;COLORETTI, FABIO;TREVISI, PAOLO
2009
Abstract
In a full factorial design (4 diets X challenge, Yes/No), 72 weaning pigs were assigned to one of the diets: Control; experimental diets, obtained with the addition of 2 g/kg free sodium butyrate (fNaB), or 0.6 g/kg fat-protected sodium butyrate (pNaB), or 2 g/kg INVE-NutriAd commercial mixture (Mix, based on 75 g/kg protected butyrate). Oral challenge with Escherichia coli K88 was done on 2/3 of pigs on d 7. Pigs were slaughtered on d 13. The mortality in challenged pigs, tended to be higher in control group (50.0 %) than in the three supplemented groups (23.5%). Growth tended to be increased averagely by the supplements (P = 0.100) after the challenge, that also significantly reduced growth. In general the diet did not affect the fecal shedding of Escherichia coli and Lactobacilli, the K88-specific IgA activity in blood, the morphology of oxyntic mucosa and the expression of H+/K+-ATPase gene. The supplementations tended to increase villous length of jejunum (P = 0.101). On the whole, growth, villous height and surviving rate can be positively affected either when the supplementation is done by free butyrate, by protected butyrate or by the special Inve Nutri-Ad product and these effects are distributed both on pigs infected or not with Escherichia coli K88.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.