In this work, the advantages of carbon nanoelectrodes (CNEs) and orgonic electrochemical transistors (OECTs) were merged to realise nanometre-sized, spearhead OECTs based on single- and double-barrel CNEs functionalised with a conducting polymer film. The needle-type OECT shows a high aspect ratio that allows its precise positioning by means of a macroscopic handle and its size is compatible with single-cell analysis. The device was characterised with respect to its electrolyte-gated behaviour and was employed as electrochemical sensor for the proof-of-concept detection of dopamine (DA) over a wide concentration range (10−12—10−6 M). Upon application of fixed drain and gate voltages (Vd = − 0.3 V, Vg = − 0.9 V, respectively), the nano-sized needle-type OECT sensor exhibited a linear response in the low pM range and from 0.002 to 7 μM DA, with a detection limit of 1 × 10−12 M.

Federica Mariani, T.Q. (2020). Needle-type organic electrochemical transistor for spatially resolved detection of dopamine. MIKROCHIMICA ACTA, 187, 1-11 [10.1007/s00604-020-04352-1].

Needle-type organic electrochemical transistor for spatially resolved detection of dopamine

Federica Mariani;Isacco Gualandi;Beatrice Fraboni;Domenica Tonelli;Erika Scavetta
;
2020

Abstract

In this work, the advantages of carbon nanoelectrodes (CNEs) and orgonic electrochemical transistors (OECTs) were merged to realise nanometre-sized, spearhead OECTs based on single- and double-barrel CNEs functionalised with a conducting polymer film. The needle-type OECT shows a high aspect ratio that allows its precise positioning by means of a macroscopic handle and its size is compatible with single-cell analysis. The device was characterised with respect to its electrolyte-gated behaviour and was employed as electrochemical sensor for the proof-of-concept detection of dopamine (DA) over a wide concentration range (10−12—10−6 M). Upon application of fixed drain and gate voltages (Vd = − 0.3 V, Vg = − 0.9 V, respectively), the nano-sized needle-type OECT sensor exhibited a linear response in the low pM range and from 0.002 to 7 μM DA, with a detection limit of 1 × 10−12 M.
2020
Federica Mariani, T.Q. (2020). Needle-type organic electrochemical transistor for spatially resolved detection of dopamine. MIKROCHIMICA ACTA, 187, 1-11 [10.1007/s00604-020-04352-1].
Federica Mariani, Thomas Quast, Corina Andronescu, Isacco Gualandi, Beatrice Fraboni, Domenica Tonelli, Erika Scavetta, Wolfgang Schuhmann
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/793796
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