The application of a novel chromatographic approach to therapeutic peptides bearing basic amino acids in their structure allowed unprecedented resolution of their related impurities (including epimeric isobaric ones), resulting in a superior analytical tool for the evaluation of the quality of these drugs in the market.
Mazzoccanti G., Manetto S., Bassan M., Foschini A., Orlandin A., Ricci A., et al. (2020). Boosting basic-peptide separation through dynamic electrostatic-repulsion reversed-phase (d-ERRP) liquid chromatography. RSC ADVANCES, 10(21), 12604-12610 [10.1039/d0ra01296c].
Boosting basic-peptide separation through dynamic electrostatic-repulsion reversed-phase (d-ERRP) liquid chromatography
Cabri W.;
2020
Abstract
The application of a novel chromatographic approach to therapeutic peptides bearing basic amino acids in their structure allowed unprecedented resolution of their related impurities (including epimeric isobaric ones), resulting in a superior analytical tool for the evaluation of the quality of these drugs in the market.File in questo prodotto:
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