Multiple system atrophy (MSA) is an adult-onset progressive neurodegenerative disorder that manifests clinically with autonomic failure, parkinsonism, and ataxia in any combination. Oligodendroglial cytoplasmatic inclusions consisting of misfoldedα-synuclein are a pathological hallmark of disease. The clinical diagnosisof MSA is typically delayed as a result of incomplete or nonspecific manifestations during early disease stages.

A critique of the second consensus criteria for multiple system atrophy

Cortelli P.;
2019

Abstract

Multiple system atrophy (MSA) is an adult-onset progressive neurodegenerative disorder that manifests clinically with autonomic failure, parkinsonism, and ataxia in any combination. Oligodendroglial cytoplasmatic inclusions consisting of misfoldedα-synuclein are a pathological hallmark of disease. The clinical diagnosisof MSA is typically delayed as a result of incomplete or nonspecific manifestations during early disease stages.
Stankovic I.; Quinn N.; Vignatelli L.; Antonini A.; Berg D.; Coon E.; Cortelli P.; Fanciulli A.; Ferreira J.J.; Freeman R.; Halliday G.; Hoglinger G.U.; Iodice V.; Kaufmann H.; Klockgether T.; Kostic V.; Krismer F.; Lang A.; Levin J.; Low P.; Mathias C.; Meissner W.G.; Kaufmann L.N.; Palma J.-A.; Panicker J.N.; Pellecchia M.T.; Sakakibara R.; Schmahmann J.; Scholz S.W.; Singer W.; Stamelou M.; Tolosa E.; Tsuji S.; Seppi K.; Poewe W.; Wenning G.K.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11585/717626
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