Pre-medicated gauze with hydrogel and hydrolat of Citrus aurantium var amara (flowers) for the prevention of microbial infections of the damaged skin

As known, one of the major problems linked to the wound care is the highest probability of infection. Until now, many studies have been developed to modify gauzes made with hydrogel, with the only function to make the wound moist, giving it also an antimicrobial action. However, articles published to date show gauzes modified with the addition of antibiotics or chemical compounds with antimicrobial action or at most essential oils like Melaleuca alternifolia (Tea Tree Oil). Our studies focused on the antimicrobial action of a hydrogel, like the gellan gel, when modified with the addition of hydrolates (Hys), natural waste products of the essential oils production method.x