Objective: To describe a case of likely etoricoxib-induced severe thrombocytopenia. Clinical Presentation and Intervention: A 32-year-old woman was referred to our hospital for disseminated petechial rash after 7 days of therapy with etoricoxib. At admission, the patient's platelet count was 3,000/mm(3). At Naranjo's scale correlation between thrombocytopenia and drug was considered as "probable." With the diagnostic tests performed we did not find other causes of thrombocytopenia. Etoricoxib was discontinued. The patient was treated with intravenous immunoglobulin and corticosteroids with a complete resolution of the thrombocytopenia in a few days. Conclusion: The prevalence of thrombocytopenia induced by etoricoxib should be studied as it may not be very rare. (C) 2019 The Author(s) Published by S. Karger AG, Basel.

Guerino Recinella, A.D.M. (2019). Probable Etoricoxib-Induced Severe Thrombocytopenia: A Case Report. MEDICAL PRINCIPLES AND PRACTICE, 28(4), 387-389 [10.1159/000496975].

Probable Etoricoxib-Induced Severe Thrombocytopenia: A Case Report

Guerino Recinella
;
Alessandro De Marchi;Enrico Pirazzoli;Giampaolo Bianchi
2019

Abstract

Objective: To describe a case of likely etoricoxib-induced severe thrombocytopenia. Clinical Presentation and Intervention: A 32-year-old woman was referred to our hospital for disseminated petechial rash after 7 days of therapy with etoricoxib. At admission, the patient's platelet count was 3,000/mm(3). At Naranjo's scale correlation between thrombocytopenia and drug was considered as "probable." With the diagnostic tests performed we did not find other causes of thrombocytopenia. Etoricoxib was discontinued. The patient was treated with intravenous immunoglobulin and corticosteroids with a complete resolution of the thrombocytopenia in a few days. Conclusion: The prevalence of thrombocytopenia induced by etoricoxib should be studied as it may not be very rare. (C) 2019 The Author(s) Published by S. Karger AG, Basel.
2019
Guerino Recinella, A.D.M. (2019). Probable Etoricoxib-Induced Severe Thrombocytopenia: A Case Report. MEDICAL PRINCIPLES AND PRACTICE, 28(4), 387-389 [10.1159/000496975].
Guerino Recinella, Alessandro De Marchi, Enrico Pirazzoli, Giampaolo Bianchi
File in questo prodotto:
File Dimensione Formato  
case report trombocitopenia 2019.pdf

accesso aperto

Tipo: Versione (PDF) editoriale
Licenza: Licenza per Accesso Aperto. Creative Commons Attribuzione - Non commerciale (CCBYNC)
Dimensione 103.19 kB
Formato Adobe PDF
103.19 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/695356
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 2
  • ???jsp.display-item.citation.isi??? 2
social impact