Objective: To describe a case of likely etoricoxib-induced severe thrombocytopenia. Clinical Presentation and Intervention: A 32-year-old woman was referred to our hospital for disseminated petechial rash after 7 days of therapy with etoricoxib. At admission, the patient's platelet count was 3,000/mm(3). At Naranjo's scale correlation between thrombocytopenia and drug was considered as "probable." With the diagnostic tests performed we did not find other causes of thrombocytopenia. Etoricoxib was discontinued. The patient was treated with intravenous immunoglobulin and corticosteroids with a complete resolution of the thrombocytopenia in a few days. Conclusion: The prevalence of thrombocytopenia induced by etoricoxib should be studied as it may not be very rare. (C) 2019 The Author(s) Published by S. Karger AG, Basel.

Probable Etoricoxib-Induced Severe Thrombocytopenia: A Case Report

Guerino Recinella
;
Alessandro De Marchi;Enrico Pirazzoli;Giampaolo Bianchi
2019

Abstract

Objective: To describe a case of likely etoricoxib-induced severe thrombocytopenia. Clinical Presentation and Intervention: A 32-year-old woman was referred to our hospital for disseminated petechial rash after 7 days of therapy with etoricoxib. At admission, the patient's platelet count was 3,000/mm(3). At Naranjo's scale correlation between thrombocytopenia and drug was considered as "probable." With the diagnostic tests performed we did not find other causes of thrombocytopenia. Etoricoxib was discontinued. The patient was treated with intravenous immunoglobulin and corticosteroids with a complete resolution of the thrombocytopenia in a few days. Conclusion: The prevalence of thrombocytopenia induced by etoricoxib should be studied as it may not be very rare. (C) 2019 The Author(s) Published by S. Karger AG, Basel.
2019
Guerino Recinella, Alessandro De Marchi, Enrico Pirazzoli, Giampaolo Bianchi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/695356
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