The organocatalytic axially enantioselective Knoevenagel condensation between prochiral cyclohexanones and oxindoles is presented. The reaction, promoted by a primary amine, proceeded smoothly and furnished unprecedented examples of novel cyclohexylidene oxindoles displaying axial chirality.

Direct Access to Alkylideneoxindoles via Axially Enantioselective Knoevenagel Condensation / Simone Crotti, Nicola Di Iorio, Chiara Artusi, Andrea Mazzanti, Paolo Righi, Giorgio Bencivenni. - In: ORGANIC LETTERS. - ISSN 1523-7060. - STAMPA. - 21:9(2019), pp. 3013-3017. [10.1021/acs.orglett.9b00505]

Direct Access to Alkylideneoxindoles via Axially Enantioselective Knoevenagel Condensation

Simone Crotti;Nicola Di Iorio;Andrea Mazzanti;Paolo Righi;Giorgio Bencivenni
2019

Abstract

The organocatalytic axially enantioselective Knoevenagel condensation between prochiral cyclohexanones and oxindoles is presented. The reaction, promoted by a primary amine, proceeded smoothly and furnished unprecedented examples of novel cyclohexylidene oxindoles displaying axial chirality.
2019
Direct Access to Alkylideneoxindoles via Axially Enantioselective Knoevenagel Condensation / Simone Crotti, Nicola Di Iorio, Chiara Artusi, Andrea Mazzanti, Paolo Righi, Giorgio Bencivenni. - In: ORGANIC LETTERS. - ISSN 1523-7060. - STAMPA. - 21:9(2019), pp. 3013-3017. [10.1021/acs.orglett.9b00505]
Simone Crotti, Nicola Di Iorio, Chiara Artusi, Andrea Mazzanti, Paolo Righi, Giorgio Bencivenni
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/690908
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