1. Why membrane proteins? 2 Many functions 3 Bioinformatics and membrane proteins: is it feasible to predict the 3D structure of a membrane protein? 4 Predicting the topology of membrane proteins 5 How many methods to predict membrane protein topology? 5.1 From theory to practice 6 Benchmarking the predictors of transmembrane topology 6.1 Testing on membrane proteins of known structure and topology 6.2 Topological experimental data 6.3 Validation towards experimental data 7 How many membrane proteins in the Human genome? 8 Membrane proteins and genetic diseases: PhD-SNP at work 9 Last but not least: 3D MODELLING of membrane proteins 10 What can currently be done in practice? 11 Can we improve?

The state of the art of membrane protein structure prediction: from sequence to 3D structure

CASADIO, RITA;FARISELLI, PIERO;MARTELLI, PIER LUIGI;PIERLEONI, ANDREA;ROSSI, IVAN;
2008

Abstract

1. Why membrane proteins? 2 Many functions 3 Bioinformatics and membrane proteins: is it feasible to predict the 3D structure of a membrane protein? 4 Predicting the topology of membrane proteins 5 How many methods to predict membrane protein topology? 5.1 From theory to practice 6 Benchmarking the predictors of transmembrane topology 6.1 Testing on membrane proteins of known structure and topology 6.2 Topological experimental data 6.3 Validation towards experimental data 7 How many membrane proteins in the Human genome? 8 Membrane proteins and genetic diseases: PhD-SNP at work 9 Last but not least: 3D MODELLING of membrane proteins 10 What can currently be done in practice? 11 Can we improve?
Modern Genome Annotation: the Biosapiens Network
309
324
Casadio R.; Fariselli P.; Martelli P.L.; Pierleoni A.; Rossi I.; von Heijne G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/67694
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