(Chemical Equation Presented) When assayed for their capacity to inhibit azo-initiated peroxidation of linoleic acid in a water/chlorobenzene two-phase system, tellurium-containing 3-pyridinols were readily regenerable by N-acetylcysteine contained in the aqueous phase. The best inhibitors quenched peroxyl radicals more efficiently than α-tocopherol, and the duration of inhibition was limited only by the availability of the thiol reducing agent. The compounds were also found to catalyze reduction of hydrogen peroxide in the presence of thiol reducing agent. © 2008 American Chemical Society
Catalytic Chain-Breaking Pyridinol Antioxidants / Kumar S.; Johansson H.; Kanda T.; Engman L.; Müller T.; Jonsson M.; Pedulli G. F.; Petrucci S.; Valgimigli L.. - In: ORGANIC LETTERS. - ISSN 1523-7060. - STAMPA. - 10:21(2008), pp. 4895-4898. [10.1021/ol801983n]
Catalytic Chain-Breaking Pyridinol Antioxidants
PEDULLI, GIAN FRANCO;PETRUCCI, SILVIA;VALGIMIGLI, LUCA
2008
Abstract
(Chemical Equation Presented) When assayed for their capacity to inhibit azo-initiated peroxidation of linoleic acid in a water/chlorobenzene two-phase system, tellurium-containing 3-pyridinols were readily regenerable by N-acetylcysteine contained in the aqueous phase. The best inhibitors quenched peroxyl radicals more efficiently than α-tocopherol, and the duration of inhibition was limited only by the availability of the thiol reducing agent. The compounds were also found to catalyze reduction of hydrogen peroxide in the presence of thiol reducing agent. © 2008 American Chemical SocietyI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
