We assessed nigral dorsolateral hyperintensity (swallow tail sign) at susceptibility-weighted imaging using 3T-MRI in 15 dementia with Lewy bodies (DLB), 11 Alzheimer's disease (AD), and 8 frontotemporal dementia (FTD) patients and 10 subjects with subjective memory complaint (SMC). More DLB patients lacked nigral hyperintesity (p<0.05). Sensitivity, specificity, and accuracy of DLB diagnosis were, respectively: 80, 64, and 73 versus AD; 80, 75, and 78 versus FTD; and 80, 90, and 84 versus SMC. Considering bilateral loss, sensitivity decreased (53) but specificity increased (82-100). Swallow tail sign loss, especially if bilateral, can be useful for DLB diagnosis.
Rizzo, G., De Blasi, R., Capozzo, R., Tortelli, R., Barulli, M.R., Liguori, R., et al. (2019). Loss of Swallow Tail Sign on Susceptibility-Weighted Imaging in Dementia with Lewy Bodies. JOURNAL OF ALZHEIMER'S DISEASE, 67(1), 61-65 [10.3233/JAD-180687].
Loss of Swallow Tail Sign on Susceptibility-Weighted Imaging in Dementia with Lewy Bodies
Rizzo, Giovanni
;Liguori, Rocco;
2019
Abstract
We assessed nigral dorsolateral hyperintensity (swallow tail sign) at susceptibility-weighted imaging using 3T-MRI in 15 dementia with Lewy bodies (DLB), 11 Alzheimer's disease (AD), and 8 frontotemporal dementia (FTD) patients and 10 subjects with subjective memory complaint (SMC). More DLB patients lacked nigral hyperintesity (p<0.05). Sensitivity, specificity, and accuracy of DLB diagnosis were, respectively: 80, 64, and 73 versus AD; 80, 75, and 78 versus FTD; and 80, 90, and 84 versus SMC. Considering bilateral loss, sensitivity decreased (53) but specificity increased (82-100). Swallow tail sign loss, especially if bilateral, can be useful for DLB diagnosis.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
