We assessed nigral dorsolateral hyperintensity (swallow tail sign) at susceptibility-weighted imaging using 3T-MRI in 15 dementia with Lewy bodies (DLB), 11 Alzheimer's disease (AD), and 8 frontotemporal dementia (FTD) patients and 10 subjects with subjective memory complaint (SMC). More DLB patients lacked nigral hyperintesity (p<0.05). Sensitivity, specificity, and accuracy of DLB diagnosis were, respectively: 80, 64, and 73 versus AD; 80, 75, and 78 versus FTD; and 80, 90, and 84 versus SMC. Considering bilateral loss, sensitivity decreased (53) but specificity increased (82-100). Swallow tail sign loss, especially if bilateral, can be useful for DLB diagnosis.
Loss of Swallow Tail Sign on Susceptibility-Weighted Imaging in Dementia with Lewy Bodies / Rizzo, Giovanni; De Blasi, Roberto; Capozzo, Rosa; Tortelli, Rosanna; Barulli, Maria Rosaria; Liguori, Rocco; Grasso, Daniela; Logroscino, Giancarlo. - In: JOURNAL OF ALZHEIMER'S DISEASE. - ISSN 1387-2877. - STAMPA. - 67:1(2019), pp. 61-65. [10.3233/JAD-180687]
Loss of Swallow Tail Sign on Susceptibility-Weighted Imaging in Dementia with Lewy Bodies
Rizzo, Giovanni
;Liguori, Rocco;
2019
Abstract
We assessed nigral dorsolateral hyperintensity (swallow tail sign) at susceptibility-weighted imaging using 3T-MRI in 15 dementia with Lewy bodies (DLB), 11 Alzheimer's disease (AD), and 8 frontotemporal dementia (FTD) patients and 10 subjects with subjective memory complaint (SMC). More DLB patients lacked nigral hyperintesity (p<0.05). Sensitivity, specificity, and accuracy of DLB diagnosis were, respectively: 80, 64, and 73 versus AD; 80, 75, and 78 versus FTD; and 80, 90, and 84 versus SMC. Considering bilateral loss, sensitivity decreased (53) but specificity increased (82-100). Swallow tail sign loss, especially if bilateral, can be useful for DLB diagnosis.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
