CRIS Current Research Information System

The graphene oxide (GO) assisted allylic alkylation of thiophenes with alcohols is presented. Mild reaction conditions and a low GO loading enabled the isolation of a range of densely functionalized thienyl and bithienyl compounds in moderate to high yields (up to 90%). The cooperative action of the Bronsted acidity, epoxide moieties, and pi-surface of the 2D-promoter is highlighted as crucial in the reaction course of the present Friedel-Crafts-type protocol.

Laura Favaretto, J.A. (2018). Graphene Oxide Promotes Site-Selective Allylic Alkylation of Thiophenes with Alcohols. ORGANIC LETTERS, 20(12), 3705-3709 [10.1021/acs.orglett.8b01531].

Graphene Oxide Promotes Site-Selective Allylic Alkylation of Thiophenes with Alcohols

Laura Favaretto;AN, JUZENG^{Membro del Collaboration Group};Marco Sambo;Assunta De Nisi^{Membro del Collaboration Group};Cristian Bettini;Manuela Melucci^Supervision;Alessandro Kovtun;Andrea Liscio;PALERMO, VINCENZO^{Membro del Collaboration Group};Andrea Bottoni^{Writing – Review & Editing};Francesco Zerbetto^{Writing – Review & Editing};Matteo Calvaresi^{Data Curation};Marco Bandini^{Writing – Original Draft Preparation}

2018

Abstract

The graphene oxide (GO) assisted allylic alkylation of thiophenes with alcohols is presented. Mild reaction conditions and a low GO loading enabled the isolation of a range of densely functionalized thienyl and bithienyl compounds in moderate to high yields (up to 90%). The cooperative action of the Bronsted acidity, epoxide moieties, and pi-surface of the 2D-promoter is highlighted as crucial in the reaction course of the present Friedel-Crafts-type protocol.

Scheda breve

Scheda completa

Scheda completa (DC)

	Anno
	
				2018
			
	Rivista
	
				ORGANIC LETTERS
			
	Codice DOI
	
				https://dx.doi.org/10.1021/acs.orglett.8b01531
			
	Citazione
	
				Laura Favaretto, J.A. (2018). Graphene Oxide Promotes Site-Selective Allylic Alkylation of Thiophenes with Alcohols. ORGANIC LETTERS, 20(12), 3705-3709 [10.1021/acs.orglett.8b01531].
			
	Tutti gli autori
	
						Laura Favaretto, Juzeng An, Marco Sambo, Assunta De Nisi, Cristian Bettini, Manuela Melucci, Alessandro Kovtun, Andrea Liscio, Vincenzo Palermo, Andre...espandi
						
	Appare nelle tipologie:
	
				1.01 Articolo in rivista

File in questo prodotto:

File	Dimensione	Formato
ol8b01531_si_001.pdf accesso aperto Tipo: File Supplementare Licenza: Licenza per accesso libero gratuito Dimensione 1.53 MB Formato Adobe PDF Visualizza/Apri	1.53 MB	Adobe PDF	Visualizza/Apri
Graphene oxide promotes.. (OLETT-Bandini-revision-no-colors)-4.pdf Open Access dal 05/06/2020 Tipo: Postprint Licenza: Licenza per Accesso Aperto. Altra tipologia di licenza compatibile con Open Access Dimensione 921.25 kB Formato Adobe PDF Visualizza/Apri	921.25 kB	Adobe PDF	Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/639182

Citazioni

2

28

25

social impact