The optimal use of sacubitril/valsartan in clinical practice needs further investigation, in particular for patients with multiple comorbidities, as such patients are usually poorly represented in clinical trials. To this end, well-documented case reports may add further evidence to the bulk of "field practice" experience on sacubitril/valsartan. We report here the case of a patient with heart failure with reduced ejection refraction with multiple comorbidities treated with sacubitril/valsartan. Overall, sacubitril/valsartan led to a prompt (within a few months) improvement in LVEF (+15%, from 38 to 53%), without any noticeable adverse events. This therapy also allowed the patient to discontinue furosemide.

Management of a Multicomorbid Patient with Heart Failure

MAGRI, GIANLUIGI;Bentivenga, Crescenzio;Cosentino, Eugenio Roberto;Degli Esposti, Daniela;Borghi, Claudio;Dormi, Ada
2017

Abstract

The optimal use of sacubitril/valsartan in clinical practice needs further investigation, in particular for patients with multiple comorbidities, as such patients are usually poorly represented in clinical trials. To this end, well-documented case reports may add further evidence to the bulk of "field practice" experience on sacubitril/valsartan. We report here the case of a patient with heart failure with reduced ejection refraction with multiple comorbidities treated with sacubitril/valsartan. Overall, sacubitril/valsartan led to a prompt (within a few months) improvement in LVEF (+15%, from 38 to 53%), without any noticeable adverse events. This therapy also allowed the patient to discontinue furosemide.
2017
Magri, Gianluigi; Bentivenga, Crescenzio; Cosentino, Eugenio Roberto; Degli Esposti, Daniela; Borghi, Claudio; Dormi, Ada
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/619075
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