Human mesenchymal stem cells (MSCs) possess well-known reparative abilities, but any defect of the immunomodulatory activity and/or the differentiation process may determine the development of human diseases, including those affecting the vascular wall. MSCs residing within the human aortic wall represent a potential cell mediator of atherosclerotic aneurysm development.
The crosstalk between vascular MSCs and inflammatory mediators determines the pro-calcific remodelling of human atherosclerotic aneurysm / Ciavarella, Carmen; Gallitto, Enrico; Ricci, Francesca; Buzzi, Marina; Stella, Andrea; Pasquinelli, Gianandrea. - In: STEM CELL RESEARCH & THERAPY. - ISSN 1757-6512. - STAMPA. - 8:1(2017), pp. 99.1-99.13. [10.1186/s13287-017-0554-x]
The crosstalk between vascular MSCs and inflammatory mediators determines the pro-calcific remodelling of human atherosclerotic aneurysm
CIAVARELLA, CARMEN;GALLITTO, ENRICO;RICCI, FRANCESCA;BUZZI, MARINA;STELLA, ANDREA;PASQUINELLI, GIANANDREA
2017
Abstract
Human mesenchymal stem cells (MSCs) possess well-known reparative abilities, but any defect of the immunomodulatory activity and/or the differentiation process may determine the development of human diseases, including those affecting the vascular wall. MSCs residing within the human aortic wall represent a potential cell mediator of atherosclerotic aneurysm development.File | Dimensione | Formato | |
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