Silicon nanowires are label-free sensors that allow real-time measurements. They are economical and pave the road for point-of-care applications but require complex readout and skilled personnel. We propose a new model and technique for sensing nanowire sensors using alternating currents (AC) to capture both magnitude and phase information from the sensor. This approach combines the advantages of complex impedance spectroscopy with the noise reduction performances of lock-in techniques. Experimental results show how modifications of the sensors with different surface chemistries lead to the same direct-current (DC) response but can be discerned using the AC approach.

Crescentini, M., Rossi, M., Ashburn, P., Lombardini, M., Sangiorgi, E., Morgan, H., et al. (2016). AC and phase sensing of nanowires for biosensing. BIOSENSORS, 6(2), 15-29 [10.3390/bios6020015].

AC and phase sensing of nanowires for biosensing

CRESCENTINI, MARCO;ROSSI, MICHELE;SANGIORGI, ENRICO;TARTAGNI, MARCO
2016

Abstract

Silicon nanowires are label-free sensors that allow real-time measurements. They are economical and pave the road for point-of-care applications but require complex readout and skilled personnel. We propose a new model and technique for sensing nanowire sensors using alternating currents (AC) to capture both magnitude and phase information from the sensor. This approach combines the advantages of complex impedance spectroscopy with the noise reduction performances of lock-in techniques. Experimental results show how modifications of the sensors with different surface chemistries lead to the same direct-current (DC) response but can be discerned using the AC approach.
2016
Crescentini, M., Rossi, M., Ashburn, P., Lombardini, M., Sangiorgi, E., Morgan, H., et al. (2016). AC and phase sensing of nanowires for biosensing. BIOSENSORS, 6(2), 15-29 [10.3390/bios6020015].
Crescentini, Marco; Rossi, Michele; Ashburn, Peter; Lombardini, Marta; Sangiorgi, Enrico; Morgan, Hywel; Tartagni, Marco
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/542835
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