PURPOSE: To better define the convulsive status epilepticus (CSE) as a possible manifestation at the onset of Panayiotopoulos syndrome (PS) and to assess its prognostic value in these children. METHODS: Children with CSE and diagnostic criteria of PS were identified, followed clinically and compared with a group of patients with PS without CSE from 1993 to 2012. RESULTS: We identified 37 patients with CSE at the onset of PS. During the same period we identified 72 children with autonomic symptoms of PS without CSE. The first episode of CSE occurred at a mean age of 6.5 years. Generalized clonic seizures were the most common ictal event and one-third of the patients required admission to Intensive Care Units. Interictal EEGs showed occipital spike activity in 31 (83.7%) subjects. Only 14 (37.8%) patients were treated with valproic acid and for two of them (5.40%) it was necessary to administer other drugs. There were no intractable cases. The overall prognosis was excellent. After the first event, 15 subjects (40.54%) experienced at least another typical PS seizure, but all patients were seizure free at the last follow-up. CONCLUSION: CSE is not uncommon in PS and it may occur at the onset of benign childhood epilepsy, without leading to a poor prognosis

Raffaella Vergaro, Duccio Maria Cordelli, Angela Miniaci, Davide Tassinari, Luca Spinardi, Andrea Pession, et al. (2014). Cerebral Ischemic Involvement in Vogt-Koyanagi-Harada Disease. PEDIATRIC NEUROLOGY, 51, 119-122 [10.1016/j.pediatrneurol.2014.03.004].

Cerebral Ischemic Involvement in Vogt-Koyanagi-Harada Disease

Duccio Maria Cordelli;PESSION, ANDREA;FRANZONI, EMILIO
2014

Abstract

PURPOSE: To better define the convulsive status epilepticus (CSE) as a possible manifestation at the onset of Panayiotopoulos syndrome (PS) and to assess its prognostic value in these children. METHODS: Children with CSE and diagnostic criteria of PS were identified, followed clinically and compared with a group of patients with PS without CSE from 1993 to 2012. RESULTS: We identified 37 patients with CSE at the onset of PS. During the same period we identified 72 children with autonomic symptoms of PS without CSE. The first episode of CSE occurred at a mean age of 6.5 years. Generalized clonic seizures were the most common ictal event and one-third of the patients required admission to Intensive Care Units. Interictal EEGs showed occipital spike activity in 31 (83.7%) subjects. Only 14 (37.8%) patients were treated with valproic acid and for two of them (5.40%) it was necessary to administer other drugs. There were no intractable cases. The overall prognosis was excellent. After the first event, 15 subjects (40.54%) experienced at least another typical PS seizure, but all patients were seizure free at the last follow-up. CONCLUSION: CSE is not uncommon in PS and it may occur at the onset of benign childhood epilepsy, without leading to a poor prognosis
2014
Raffaella Vergaro, Duccio Maria Cordelli, Angela Miniaci, Davide Tassinari, Luca Spinardi, Andrea Pession, et al. (2014). Cerebral Ischemic Involvement in Vogt-Koyanagi-Harada Disease. PEDIATRIC NEUROLOGY, 51, 119-122 [10.1016/j.pediatrneurol.2014.03.004].
Raffaella Vergaro;Duccio Maria Cordelli;Angela Miniaci;Davide Tassinari;Luca Spinardi;Andrea Pession;Emilio Franzoni
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/398458
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