The HR-MAS is an ideal technique for the investigation of intact tissue specimens (10-50 mg) and permits the obtainment of spectra with a resolution comparable to that observed in solution in a time that does not exceed a half of an hour for a routine analysis. The potentialities of HR-MAS NMR spectroscopy in the identification of the metabolites characterizing the healthy gastric mucosa are here presented. The direct inspection of the 1D 1H NMR spectra enables only few metabolites to be confidently assigned, and the use of selected 2D experiments strongly amplify the analytical effectiveness of the technique. © 2006 Wiley Periodicals, Inc.

HR-MAS NMR spectroscopy in the characterization of human tissue: application to healthy gastric mucosa / L. Schenetti; A. Mucci; F. Parenti; R. Cagnoli; V. Righi; M.R. Tosi; V. Tugnoli. - In: CONCEPTS IN MAGNETIC RESONANCE. PART A, BRIDGING EDUCATION AND RESEARCH.. - ISSN 1546-6086. - STAMPA. - 28:6(2006), pp. 430-443. [10.1002/cmr.a.20068]

HR-MAS NMR spectroscopy in the characterization of human tissue: application to healthy gastric mucosa.

RIGHI, VALERIA;TUGNOLI, VITALIANO
2006

Abstract

The HR-MAS is an ideal technique for the investigation of intact tissue specimens (10-50 mg) and permits the obtainment of spectra with a resolution comparable to that observed in solution in a time that does not exceed a half of an hour for a routine analysis. The potentialities of HR-MAS NMR spectroscopy in the identification of the metabolites characterizing the healthy gastric mucosa are here presented. The direct inspection of the 1D 1H NMR spectra enables only few metabolites to be confidently assigned, and the use of selected 2D experiments strongly amplify the analytical effectiveness of the technique. © 2006 Wiley Periodicals, Inc.
2006
HR-MAS NMR spectroscopy in the characterization of human tissue: application to healthy gastric mucosa / L. Schenetti; A. Mucci; F. Parenti; R. Cagnoli; V. Righi; M.R. Tosi; V. Tugnoli. - In: CONCEPTS IN MAGNETIC RESONANCE. PART A, BRIDGING EDUCATION AND RESEARCH.. - ISSN 1546-6086. - STAMPA. - 28:6(2006), pp. 430-443. [10.1002/cmr.a.20068]
L. Schenetti; A. Mucci; F. Parenti; R. Cagnoli; V. Righi; M.R. Tosi; V. Tugnoli
File in questo prodotto:
Eventuali allegati, non sono esposti

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/33532
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 32
  • ???jsp.display-item.citation.isi??? 26
social impact