We present the first case of salvage retroperitoneal lymph node dissection based on the results of (18)F-FACBC PET/CT performed for a prostate-specific antigen relapse after radical prostatectomy. The patients underwent (11)C-choline PET/CT, which turned out negative, while (18)F-FACBC PET/CT visualized two lymph node metastases confirmed at pathological examination. Preliminary clinical reports showed an improvement in the detection rate of 20-40% for (18)F-FACBC in comparison with (11)C-choline, rendering the (18)F-FACBC the potential radiotracer of the future. Salvage surgery for prostate cancer is a fascinating but controversial approach. New diagnostic tools may improve its potential by increasing the assessment and the selection of the patients.
First Case of F-FACBC PET/CT-Guided Salvage Retroperitoneal Lymph Node Dissection for Disease Relapse after Radical Prostatectomy for Prostate Cancer and Negative (11)C-Choline PET/CT: New Imaging Techniques May Expand Pioneering Approaches / Schiavina R;Concetti S;BRUNOCILLA E.;Nanni C;Borghesi M;Gentile G;Cevenini M;Bianchi L;Molinaroli E;Fanti S;Martorana G. - In: UROLOGY INTERNATIONAL. - ISSN 1352-9544. - STAMPA. - 92:(2014), pp. 242-245. [10.1159/000354730]
First Case of F-FACBC PET/CT-Guided Salvage Retroperitoneal Lymph Node Dissection for Disease Relapse after Radical Prostatectomy for Prostate Cancer and Negative (11)C-Choline PET/CT: New Imaging Techniques May Expand Pioneering Approaches.
SCHIAVINA, RICCARDO;CONCETTI, SERGIO;BRUNOCILLA, EUGENIO;BORGHESI, MARCO;GENTILE, GIORGIO;BIANCHI, LORENZO;FANTI, STEFANO;MARTORANA, GIUSEPPE
2014
Abstract
We present the first case of salvage retroperitoneal lymph node dissection based on the results of (18)F-FACBC PET/CT performed for a prostate-specific antigen relapse after radical prostatectomy. The patients underwent (11)C-choline PET/CT, which turned out negative, while (18)F-FACBC PET/CT visualized two lymph node metastases confirmed at pathological examination. Preliminary clinical reports showed an improvement in the detection rate of 20-40% for (18)F-FACBC in comparison with (11)C-choline, rendering the (18)F-FACBC the potential radiotracer of the future. Salvage surgery for prostate cancer is a fascinating but controversial approach. New diagnostic tools may improve its potential by increasing the assessment and the selection of the patients.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
