CRIS Current Research Information System
IRIS è la soluzione IT che facilita la raccolta e la gestione dei dati relativi alle attività e ai prodotti della ricerca. Fornisce a ricercatori, amministratori e valutatori gli strumenti per monitorare i risultati della ricerca, aumentarne la visibilità e allocare in modo efficace le risorse disponibili.
EnglishA consistent rate of patients who are classified as “node-negative” after radical prostatectomy and pelvic lymph-node dissection (PLND) experience a nodal disease relapse. Routine pathological examination can miss micro-metastatic tumor foci in the lymph nodes (LN) of patients with prostate cancer (PCa), resulting in confused tumor staging and clinical decision-making. The aim of the present perspective study was to evaluate the impact of micro-metastasis assessed by serial section (SS), immunohistochemistry (IHC) and real time-Polymerase Chain Reaction (RT-PCR) in patient submitted to radical prostatectomy with extended PLND.
| Titolo: | Detection of nodal micro metastases with serial section, immunohistochemistry and real time-polymerase chain reaction in intermediate and high risk prostate cancer patients submitted to radical prostatectomy with extended pelvic lymph node dissection: A perspective study |
| Autore/i: | SCHIAVINA, RICCARDO; ROMAGNOLI, DANIELE; BORGHESI, MARCO; ROCCA C.; ZUKERMAN, ZIV; SAVINI, ANDREA; DABABNEH, HUSSAM; BARBIERI, BARBARA; BRUNOCILLA, EUGENIO; MANFERRARI, FABIO; MARTORANA, GIUSEPPE |
| Autore/i Unibo: | |
| Anno: | 2012 |
| Rivista: | |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/S1569-9056(12)60120-1 |
| Abstract: | A consistent rate of patients who are classified as “node-negative” after radical prostatectomy and pelvic lymph-node dissection (PLND) experience a nodal disease relapse. Routine pathological examination can miss micro-metastatic tumor foci in the lymph nodes (LN) of patients with prostate cancer (PCa), resulting in confused tumor staging and clinical decision-making. The aim of the present perspective study was to evaluate the impact of micro-metastasis assessed by serial section (SS), immunohistochemistry (IHC) and real time-Polymerase Chain Reaction (RT-PCR) in patient submitted to radical prostatectomy with extended PLND. |
| Data prodotto definitivo in UGOV: | 2014-03-24 17:00:47 |
| Appare nelle tipologie: | 1.01 Articolo in rivista |
File in questo prodotto:
Copyright © 2021