Persistent infection with human papillomavirus (HPV) induces cervical cancer. Here, we describe a sensitive, specific, and rapid assay for high-risk HPV16 and 18 detection by isothermal helicase-dependent amplification. This method can be used as cost-effective diagnostic method for low-income countries, where highest incidences worldwide of cervical cancer are registered.
Daniela Barbieri, Simona Venturoli, Frank Rösl, Bladimiro Rincon-Orozco (2014). Detection of high-risk Human Papilloma Virus type 16 and 18 using Isothermal Helicase-Dependent Amplification. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 79, 178-182 [10.1016/j.diagmicrobio.2014.02.012].
Detection of high-risk Human Papilloma Virus type 16 and 18 using Isothermal Helicase-Dependent Amplification
BARBIERI, DANIELA;VENTUROLI, SIMONA;
2014
Abstract
Persistent infection with human papillomavirus (HPV) induces cervical cancer. Here, we describe a sensitive, specific, and rapid assay for high-risk HPV16 and 18 detection by isothermal helicase-dependent amplification. This method can be used as cost-effective diagnostic method for low-income countries, where highest incidences worldwide of cervical cancer are registered.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
