Summary. Transglutaminases have a range of catalytic activities, most of which concern the post-translational modification of proteins. The most important of these activities, both in terms of biology and biotechnology, is the cross-linking of proteins into large supramolecular networks. The widespread use of transglutaminases in research, medicine and industry has increased the demand for an inexpensive, efficient and safe source of recombinant enzymes. We describe initial results concerning the production of a mammalian transglutaminase in transgenic rice plants as a first step towards the large-scale molecular farming of this enzyme.
Capell T., Claparols M. I., Del Duca S., Bassie L., Miro B., Rodriguez-Montesinos J., et al. (2004). Producing transglutaminases by molecular farming in plants: minireview article. AMINO ACIDS, 26, 419-423 [10.1007/s00726-004-0086-4].
Producing transglutaminases by molecular farming in plants: minireview article.
DEL DUCA, STEFANO;SERAFINI FRACASSINI, DONATELLA
2004
Abstract
Summary. Transglutaminases have a range of catalytic activities, most of which concern the post-translational modification of proteins. The most important of these activities, both in terms of biology and biotechnology, is the cross-linking of proteins into large supramolecular networks. The widespread use of transglutaminases in research, medicine and industry has increased the demand for an inexpensive, efficient and safe source of recombinant enzymes. We describe initial results concerning the production of a mammalian transglutaminase in transgenic rice plants as a first step towards the large-scale molecular farming of this enzyme.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
