Surface functionalization of artificial polymeric biomaterials has been extensively studied as a useful strategy to improve material biointegration, promoting cell adhesion, proliferation and differentiation, without altering the main bulk properties of the material [1,2]. Electrospun nanofibrous scaffolds made of poly(L-lactic acid) (PLLA), mimicking the fibrillar arrangement of the extracellular matrix, have been widely used in tissue engineering applications. In this work the effect of atmospheric pressure non-thermal plasma surface functionalization of PLLA electrospun scaffold is investigated.
ML Focarete, LS Dolci, SD Quiroga, M Gherardi, R Laurita, A Liguori, et al. (2013). Surface modification of poly(L-lactic acid) electrospun scaffold by atmospheric plasma: scaffold properties and fibroblast morphological response.
Surface modification of poly(L-lactic acid) electrospun scaffold by atmospheric plasma: scaffold properties and fibroblast morphological response
FOCARETE, MARIA LETIZIA;DOLCI, LUISA STELLA;GHERARDI, MATTEO;LAURITA, ROMOLO;LIGUORI, ANNA;GHEDINI, EMANUELE;SANIBONDI, PAOLO;FIORANI, ANDREA;CALZA', LAURA;COLOMBO, VITTORIO
2013
Abstract
Surface functionalization of artificial polymeric biomaterials has been extensively studied as a useful strategy to improve material biointegration, promoting cell adhesion, proliferation and differentiation, without altering the main bulk properties of the material [1,2]. Electrospun nanofibrous scaffolds made of poly(L-lactic acid) (PLLA), mimicking the fibrillar arrangement of the extracellular matrix, have been widely used in tissue engineering applications. In this work the effect of atmospheric pressure non-thermal plasma surface functionalization of PLLA electrospun scaffold is investigated.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
