Subject-specific finite element models have been used to predict stress-state and fracture risk in individual patients. While many studies analysed quasi-axial loading configurations, only few works simulated sideways load configurations, such as those arising in a fall. The majority among these latter directly predicted bone strength, without assessing elastic strain prediction accuracy. The aim of the present work was to evaluate if a subject-specific finite element modelling technique from CT data that accurately predicted strains in quasi-axial loading configurations is suitable to accurately predict strains also when applying low magnitude loads in sideways configurations. To this aim, a combined numerical-experimental study was performed to compare finite element predicted strains with strain-gauge measurements from three cadaver proximal femurs instrumented with sixteen strain rosettes and tested non-destructively under twelve loading configurations, spanning a wide cone (0-30 degrees for both adduction and internal rotation angles) of sideways fall scenarios. The results of the present study evidenced a satisfactory agreement between experimentally measured and predicted strains (R(2) greater than 0.9, RMSE% lower than 10%) and displacements. The achieved strain prediction accuracy is comparable to those obtained in state of the art studies in quasi-axial loading configurations. Still, the presence of the highest strain prediction errors (around 30%) in the lateral neck aspect would deserve attention in future studies targeting bone failure.

Grassi L., Schileo E., Taddei F., Zani L., Juszczyk M., Cristofolini L., et al. (2012). Accuracy of finite element predictions in sideways load configurations for the proximal human femur. JOURNAL OF BIOMECHANICS, 45(2), 394-399 [10.1016/j.jbiomech.2011.10.019].

Accuracy of finite element predictions in sideways load configurations for the proximal human femur

CRISTOFOLINI, LUCA;Viceconti M.
2012

Abstract

Subject-specific finite element models have been used to predict stress-state and fracture risk in individual patients. While many studies analysed quasi-axial loading configurations, only few works simulated sideways load configurations, such as those arising in a fall. The majority among these latter directly predicted bone strength, without assessing elastic strain prediction accuracy. The aim of the present work was to evaluate if a subject-specific finite element modelling technique from CT data that accurately predicted strains in quasi-axial loading configurations is suitable to accurately predict strains also when applying low magnitude loads in sideways configurations. To this aim, a combined numerical-experimental study was performed to compare finite element predicted strains with strain-gauge measurements from three cadaver proximal femurs instrumented with sixteen strain rosettes and tested non-destructively under twelve loading configurations, spanning a wide cone (0-30 degrees for both adduction and internal rotation angles) of sideways fall scenarios. The results of the present study evidenced a satisfactory agreement between experimentally measured and predicted strains (R(2) greater than 0.9, RMSE% lower than 10%) and displacements. The achieved strain prediction accuracy is comparable to those obtained in state of the art studies in quasi-axial loading configurations. Still, the presence of the highest strain prediction errors (around 30%) in the lateral neck aspect would deserve attention in future studies targeting bone failure.
2012
Grassi L., Schileo E., Taddei F., Zani L., Juszczyk M., Cristofolini L., et al. (2012). Accuracy of finite element predictions in sideways load configurations for the proximal human femur. JOURNAL OF BIOMECHANICS, 45(2), 394-399 [10.1016/j.jbiomech.2011.10.019].
Grassi L.; Schileo E.; Taddei F.; Zani L.; Juszczyk M.; Cristofolini L.; Viceconti M.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/128105
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