INTRODUCTION: Morvan chorea is an antibody-mediated limbic encephalopathy characterized by severe insomnia, mental confusion, hallucinations, enacted dreams, hyperhidrosis, and neuromyotonia. CASE DESCRIPTION: In a 78 years old man presenting with progressive insomnia apathy and depression, a video-polysomnogram documented enacted dreams mimicking daily life activity (oneiric stupor). This finding led us to perform a search for serum antibodies to voltage-gated K+ channels, which was positive. A diagnosis of Morvan chorea was done. The patient underwent plasma exchange with complete resolution of the clinical picture. CONCLUSIONS: Oneiric stupor may represent a useful precocious diagnostic marker in Morvan chorea.

Provini F., Marconi S., Amadori M., Guaraldi P., Pierangeli G., Cortelli P., et al. (2011). Morvan chorea and agrypnia excitata: when video-polysomnographic recording guides the diagnosis. SLEEP MEDICINE, 12(10), 1041-1043 [10.1016/j.sleep.2011.05.005].

Morvan chorea and agrypnia excitata: when video-polysomnographic recording guides the diagnosis.

PROVINI, FEDERICA;MARCONI, SARA;AMADORI, MARCELLO;PIERANGELI, GIULIA;CORTELLI, PIETRO;TINUPER, PAOLO
2011

Abstract

INTRODUCTION: Morvan chorea is an antibody-mediated limbic encephalopathy characterized by severe insomnia, mental confusion, hallucinations, enacted dreams, hyperhidrosis, and neuromyotonia. CASE DESCRIPTION: In a 78 years old man presenting with progressive insomnia apathy and depression, a video-polysomnogram documented enacted dreams mimicking daily life activity (oneiric stupor). This finding led us to perform a search for serum antibodies to voltage-gated K+ channels, which was positive. A diagnosis of Morvan chorea was done. The patient underwent plasma exchange with complete resolution of the clinical picture. CONCLUSIONS: Oneiric stupor may represent a useful precocious diagnostic marker in Morvan chorea.
2011
Provini F., Marconi S., Amadori M., Guaraldi P., Pierangeli G., Cortelli P., et al. (2011). Morvan chorea and agrypnia excitata: when video-polysomnographic recording guides the diagnosis. SLEEP MEDICINE, 12(10), 1041-1043 [10.1016/j.sleep.2011.05.005].
Provini F.; Marconi S.; Amadori M.; Guaraldi P.; Pierangeli G.; Cortelli P.; Lugaresi E.; Montagna P.; Tinuper P.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/112746
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