INTRODUCTION: Morvan chorea is an antibody-mediated limbic encephalopathy characterized by severe insomnia, mental confusion, hallucinations, enacted dreams, hyperhidrosis, and neuromyotonia. CASE DESCRIPTION: In a 78 years old man presenting with progressive insomnia apathy and depression, a video-polysomnogram documented enacted dreams mimicking daily life activity (oneiric stupor). This finding led us to perform a search for serum antibodies to voltage-gated K+ channels, which was positive. A diagnosis of Morvan chorea was done. The patient underwent plasma exchange with complete resolution of the clinical picture. CONCLUSIONS: Oneiric stupor may represent a useful precocious diagnostic marker in Morvan chorea.
Morvan chorea and agrypnia excitata: when video-polysomnographic recording guides the diagnosis / Provini F.; Marconi S.; Amadori M.; Guaraldi P.; Pierangeli G.; Cortelli P.; Lugaresi E.; Montagna P.; Tinuper P.. - In: SLEEP MEDICINE. - ISSN 1389-9457. - ELETTRONICO. - 12:10(2011), pp. 1041-1043. [10.1016/j.sleep.2011.05.005]
Morvan chorea and agrypnia excitata: when video-polysomnographic recording guides the diagnosis.
PROVINI, FEDERICA;MARCONI, SARA;AMADORI, MARCELLO;PIERANGELI, GIULIA;CORTELLI, PIETRO;TINUPER, PAOLO
2011
Abstract
INTRODUCTION: Morvan chorea is an antibody-mediated limbic encephalopathy characterized by severe insomnia, mental confusion, hallucinations, enacted dreams, hyperhidrosis, and neuromyotonia. CASE DESCRIPTION: In a 78 years old man presenting with progressive insomnia apathy and depression, a video-polysomnogram documented enacted dreams mimicking daily life activity (oneiric stupor). This finding led us to perform a search for serum antibodies to voltage-gated K+ channels, which was positive. A diagnosis of Morvan chorea was done. The patient underwent plasma exchange with complete resolution of the clinical picture. CONCLUSIONS: Oneiric stupor may represent a useful precocious diagnostic marker in Morvan chorea.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
