We assessed the antifungal susceptibility of 86 Aspergillus fumigatus strains by a phenotypic test. Azole sensitivity was compared to a molecular test detecting cyp51A mutations. Azole resistance was quite limited, whereas strains from COVID-19 patients showed higher amphotericin B MICs. The molecular test showed a 100 %-agreement with the phenotypic assay.
Liberatore, A., Lombardi, G., Lombardo, D., Lazzarotto, T., Foschi, C., Ambretti, S. (2025). Antifungal susceptibility of a collection of Aspergillus fumigatus strains isolated from patients with invasive pulmonary aspergillosis and COVID-19 associated aspergillosis. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 113(1), 1-4 [10.1016/j.diagmicrobio.2025.116884].
Antifungal susceptibility of a collection of Aspergillus fumigatus strains isolated from patients with invasive pulmonary aspergillosis and COVID-19 associated aspergillosis
Lazzarotto, Tiziana;Foschi, Claudio
;Ambretti, Simone
2025
Abstract
We assessed the antifungal susceptibility of 86 Aspergillus fumigatus strains by a phenotypic test. Azole sensitivity was compared to a molecular test detecting cyp51A mutations. Azole resistance was quite limited, whereas strains from COVID-19 patients showed higher amphotericin B MICs. The molecular test showed a 100 %-agreement with the phenotypic assay.| File | Dimensione | Formato | |
|---|---|---|---|
|
1-s2.0-S073288932500207X-main.pdf
accesso aperto
Tipo:
Versione (PDF) editoriale / Version Of Record
Licenza:
Licenza per Accesso Aperto. Creative Commons Attribuzione (CCBY)
Dimensione
1.17 MB
Formato
Adobe PDF
|
1.17 MB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
