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LOI, MANUELA

LOI, MANUELA  

DIBINEM - DIPARTIMENTO DI SCIENZE BIOMEDICHE E NEUROMOTORIE  

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Risultati 1 - 20 di 25 (tempo di esecuzione: 0.061 secondi).
Titolo Autore(i) Anno Periodico Editore Tipo File
Adult-Onset Deletion of CDKL5 in Forebrain Glutamatergic Neurons Impairs Synaptic Integrity and Behavior in Mice Mottolese, Nicola; Iannibelli, Feliciana; Candini, Giulia; Trebbi, Federica; Loi, Manuela; Bove, ...Angelica Marina; Medici, Giorgio; Xiong, Zhi-Qi; Ciani, Elisabetta; Trazzi, Stefania 2025-01-01 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 1.01 Articolo in rivista ijms-26-06626-manuscript.pdf; ijms-3733101-supplementary.pdf
AR-A014418-based dual Glycogen Synthase Kinase 3β/Histone Deacetylase inhibitors as potential therapeutics for Alzheimer's disease Santini, Alan; Tassinari, Elisa; Altomare, Alessandra; Loi, Manuela; Ciani, Elisabetta; Trazzi, S...tefania; Piccarducci, Rebecca; Daniele, Simona; Martini, Claudia; Pagliarani, Barbara; Tarozzi, Andrea; Bersani, Matteo; Spyrakis, Francesca; Danková, Daniela; Poeta, Eleonora; Raimondi, Simone; Davani, Lara; Aldini, Giancarlo; Andrisano, Vincenza; De Simone, Angela; Milelli, Andrea 2025-01-01 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 1.01 Articolo in rivista AR-A014418-based dual Glycogen Synthase Kinase 3β_Histone Deacetylase inhibitors as potential therapeutics for Alzheimer_s disease.pdf; 1-s2.0-S0223523425006038-mmc1.docx
Beneficial Antioxidant Effects of Coenzyme Q10 in In Vitro and In Vivo Models of CDKL5 Deficiency Disorder Loi, Manuela; Valenti, Francesca; Medici, Giorgio; Mottolese, Nicola; Candini, Giulia; Bove, ANGE...LICA MARINA; Trebbi, Federica; Pincigher, Luca; Fato, Romana; Bergamini, Christian; Trazzi, Stefania; Ciani, Elisabetta 2025-01-01 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 1.01 Articolo in rivista ijms-26-02204-v3.pdf; ijms-26-02204-s001.zip
Design, synthesis and pharmacological evaluation of multitarget GPR40 agonists/HDAC6 inhibitors for Alzheimer's disease Pinheiro, P. D. S. M.; De Chirico, F.; Loi, M.; Trazzi, S.; Ciani, E.; Rodrigues, D. A.; Alves, M.... A.; Lima, L. M.; Milelli, A.; Monti, B.; Manssour Fraga, C. A.; Bolognesi, M. L. 2025-01-01 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 1.01 Articolo in rivista -
Lactic acid bacteria as microbial cell factories for the in vivo delivery of therapeutic proteins as secretable TAT fusion products Medici, Giorgio; Candini, Giulia; Mottolese, Nicola; Uguagliati, Beatrice; Trebbi, Federica; Loi,... Manuela; Bove, Angelica Marina; Stojanov, Spase; Esposito, Erika; Vitagliano, Rosalba; D'Amico, Federica; Turroni, Silvia; Fiori, Jessica; Berlec, Aleš; Trazzi, Stefania; Ciani, Elisabetta 2025-01-01 JOURNAL OF BIOLOGICAL ENGINEERING - 1.01 Articolo in rivista 13036_2025_Article_538.pdf; 13036_2025_538_MOESM1_ESM.pdf
Safety and efficacy of Igk-TATk-CDKL5 gene therapy in mosaic CDKL5 deficiency Medici, Giorgio; Tassinari, Marianna; Loi, Manuela; Bove, Angelica Marina; Garofani, Beatrice Cas...adei; Volpedo, Greta; Mottolese, Nicola; Matteoli, Gabriele; Lo Martire, Viviana; Berteotti, Chiara; Candini, Giulia; Trebbi, Federica; Riva, Antonella; Striano, Pasquale; Zoccoli, Giovanna; Curia, Giulia; Trazzi, Stefania; Ciani, Elisabetta 2025-01-01 NEUROTHERAPEUTICS - 1.01 Articolo in rivista -
Effects of a ciliary neurotrophic factor (CNTF) small-molecule peptide mimetic in an in vitro and in vivo model of CDKL5 deficiency disorder Mottolese, Nicola; Loi, Manuela; Trazzi, Stefania; Tassinari, Marianna; Uguagliati, Beatrice; Can...dini, Giulia; Iqbal, Khalid; Medici, Giorgio; Ciani, Elisabetta 2024-01-01 JOURNAL OF NEURODEVELOPMENTAL DISORDERS - 1.01 Articolo in rivista Mottolese et al., 2024_JNDD_Manuscript.pdf
First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer’s Disease Santini, A.; Tassinari, E.; Poeta, E.; Loi, M.; Ciani, E.; Trazzi, S.; Piccarducci, R.; Daniele, ...S.; Martini, C.; Pagliarani, B.; Tarozzi, A.; Bersani, M.; Spyrakis, F.; Danková, D.; Olsen, C. A.; Soldati, R.; Tumiatti, V.; Montanari, S.; De Simone, A.; Milelli, A. 2024-01-01 ACS CHEMICAL NEUROSCIENCE - 1.01 Articolo in rivista acs-cn.pdf
Cardiac Functional and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder Loi, Manuela; Bastianini, Stefano; Candini, Giulia; Rizzardi, Nicola; Medici, Giorgio; Papa, Vale...ntina; Gennaccaro, Laura; Mottolese, Nicola; Tassinari, Marianna; Uguagliati, Beatrice; Berteotti, Chiara; Martire, Viviana Lo; Zoccoli, Giovanna; Cenacchi, Giovanna; Trazzi, Stefania; Bergamini, Christian; Ciani, Elisabetta 2023-01-01 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 1.01 Articolo in rivista 2023, Cardiac Functional and Structural Abnormalities, Loi-Bastianini.pdf; ijms-24-05552-s001.zip
Early-onset brain alterations during postnatal development in a mouse model of CDKL5 deficiency disorder Tassinari, Marianna; Uguagliati, Beatrice; Trazzi, Stefania; Cerchier, Camilla Bruna; Cavina, Ott...avia Vera; Mottolese, Nicola; Loi, Manuela; Candini, Giulia; Medici, Giorgio; Ciani, Elisabetta 2023-01-01 NEUROBIOLOGY OF DISEASE - 1.01 Articolo in rivista 2023, Early-onset brain alterations during postnatal development in a mouse, Tassinari-Uguagliati.pdf; ScienceDirect_files_24Jul2023_10-41-05.864.zip
Voluntary Running Improves Behavioral and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder Mottolese, Nicola; Uguagliati, Beatrice; Tassinari, Marianna; Cerchier, Camilla Bruna; Loi, Manue...la; Candini, Giulia; Rimondini, Roberto; Medici, Giorgio; Trazzi, Stefania; Ciani, Elisabetta 2023-01-01 BIOMOLECULES - 1.01 Articolo in rivista biomolecules-13-01396.pdf
Expression of a Secretable, Cell-Penetrating CDKL5 Protein Enhances the Efficacy of Gene Therapy for CDKL5 Deficiency Disorder Medici, Giorgio; Tassinari, Marianna; Galvani, Giuseppe; Bastianini, Stefano; Gennaccaro, Laura; ...Loi, Manuela; Mottolese, Nicola; Alvente, Sara; Berteotti, Chiara; Sagona, Giulia; Lupori, Leonardo; Candini, Giulia; Baggett, Helen Rappe; Zoccoli, Giovanna; Giustetto, Maurizio; Muotri, Alysson; Pizzorusso, Tommaso; Nakai, Hiroyuki; Trazzi, Stefania; Ciani, Elisabetta 2022-01-01 NEUROTHERAPEUTICS - 1.01 Articolo in rivista s13311-022-01295-8.pdf; supplemantary materials.zip
Luteolin Treatment Ameliorates Brain Development and Behavioral Performance in a Mouse Model of CDKL5 Deficiency Disorder Tassinari, Marianna; Mottolese, Nicola; Galvani, Giuseppe; Ferrara, Domenico; Gennaccaro, Laura; ...Loi, Manuela; Medici, Giorgio; Candini, Giulia; Rimondini, Roberto; Ciani, Elisabetta; Trazzi, Stefania 2022-01-01 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 1.01 Articolo in rivista ijms-23-08719.pdf; ijms-23-08719-s001.zip
A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder Laura Gennaccaro, Claudia Fuchs, Manuela Loi, Vincenzo Roncacè, Stefania Trazzi, Yassine Ait-Bali..., Giuseppe Galvani, Anna Cecilia Berardi, Giorgio Medici, Marianna Tassinari, Elisa Ren, Roberto Rimondini, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani 2021-01-01 NEUROBIOLOGY OF DISEASE - 1.01 Articolo in rivista Gennaccaro et al 2021GABA.pdf; Supplementary data.docx
Age-related cognitive and motor decline in a mouse model of CDKL5 deficiency disorder is associated with increased neuronal senescence and death Gennaccaro L.; Fuchs C.; Loi M.; Pizzo R.; Alvente S.; Berteotti C.; Lupori L.; Sagona G.; Galvan...i G.; Gurgone A.; Raspanti A.; Medici G.; Tassinari M.; Trazzi S.; Ren E.; Rimondini R.; Pizzorusso T.; Zoccoli G.; Giustetto M.; Ciani E. 2021-01-01 AGING AND DISEASE - 1.01 Articolo in rivista Gennaccaro et al 2021Age.pdf
Inhibition of microglia over-activation restores neuronal survival and maturation in a mouse model of CDKL5 deficiency disorder Nicola Mottolese, Giuseppe Galvani, Laura Gennaccaro, Manuela Loi, Giorgio Medici, Marianna Tassi...nari, Stefania Trazzi, Elisabetta Ciani 2021-01-01 - - 4.03 Poster -
Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder Galvani, Giuseppe; Mottolese, Nicola; Gennaccaro, Laura; Loi, Manuela; Medici, Giorgio; Tassinari..., Marianna; Fuchs, Claudia; Ciani, Elisabetta; Trazzi, Stefania 2021-01-01 JOURNAL OF NEUROINFLAMMATION - 1.01 Articolo in rivista Galvani et al 2021.pdf
Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder Loi, Manuela; Gennaccaro, Laura; Fuchs, Claudia; Trazzi, Stefania; Medici, Giorgio; Galvani, Gius...eppe; Mottolese, Nicola; Tassinari, Marianna; Giorgini, Roberto Rimondini; Milelli, Andrea; Ciani, Elisabetta 2021-01-01 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 1.01 Articolo in rivista Loi et al 2021.pdf; ijms-1212824-supplementary.pdf
Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons Loi, M.; Trazzi, S.; Fuchs, C.; Galvani, G.; Medici, G.; Gennaccaro, L.; Tassinari, M.; Ciani, E. 2020-01-01 MOLECULAR NEUROBIOLOGY - 1.01 Articolo in rivista Loi et al.pdf; 12035_2020_1884_MOESM1_ESM.pdf
Long term breeding of the Lmna G609G progeric mouse: Characterization of homozygous and heterozygous models Zaghini A.; Sarli G.; Barboni C.; Sanapo M.; Pellegrino V.; Diana A.; Linta N.; Rambaldi J.; D'Ap...ice M.R.; Murdocca M.; Baleani M.; Baruffaldi F.; Fognani R.; Mecca R.; Festa A.; Papparella S.; Paciello O.; Prisco F.; Capanni C.; Loi M.; Schena E.; Lattanzi G.; Squarzoni S. 2020-01-01 EXPERIMENTAL GERONTOLOGY - 1.01 Articolo in rivista Progerie - lavoro colonie.pdf