BRUNO, SAMANTHA
BRUNO, SAMANTHA
DIPARTIMENTO DI SCIENZE MEDICHE E CHIRURGICHE
Assegnisti
Bitter Taste Receptor Agonist Denatonium Inhibits Stemness Characteristics in Hematopoietic Stem/Progenitor Cells
2024 Pensato V.; Laginestra M.A.; Falvo P.; Orecchioni S.; Talarico G.; De Marchi E.; Bruno S.; Mongiorgi S.; Mitola G.; Bertolini F.; Adinolfi E.; Cavo M.; Curti A.; Salvestrini V.
SETD2 non genomic loss of function in advanced systemic mastocytosis is mediated by an Aurora kinase A/MDM2 axis and can be therapeutically targeted
2023 Mancini M.; Monaldi C.; De Santis S.; Papayannidis C.; Rondoni M.; Sartor C.; Bruno S.; Pagano L.; Criscuolo M.; Zanotti R.; Bonifacio M.; Tosi P.; Arock M.; Valent P.; Cavo M.; Soverini S.
CDC20 in and out of mitosis: a prognostic factor and therapeutic target in hematological malignancies
2022 Bruno S.; Ghelli Luserna di Rora A.; Napolitano R.; Soverini S.; Martinelli G.; Simonetti G.
CML-184 A Novel Droplet Digital PCR Strategy for Rapid and Sensitive Detection of BCR::ABL1 Kinase Domain Mutations Conferring Resistance to Second-Generation Tyrosine Kinase Inhibitors
2022 de Santis S.; Monaldi C.; Martelli M.; Mancini M.; Bruno S.; Castagnetti F.; Gugliotta G.; Polakova K.M.; Ernst T.; Maar D.; Corner A.; Cavo M.; Soverini S.
Combined Inhibition of Polo-like Kinase-1 and Wee1 as a New Therapeutic Strategy to Induce Apoptotic Cell Death in Neoplastic Mast Cells
2022 Mancini M.; Monaldi C.; De Santis S.; Rondoni M.; Papayannidis C.; Sartor C.; Curti A.; Bruno S.; Cavo M.; Soverini S.
Droplet digital PCR for the detection of second-generation tyrosine kinase inhibitor-resistant BCR::ABL1 kinase domain mutations in chronic myeloid leukemia
2022 Soverini, S.; De Santis, S.; Martelli, M.; Monaldi, C.; Castagnetti, F.; Gugliotta, G.; Papayannidis, C.; Mancini, M.; Bruno, S.; Venturi, C.; Machova Polakova, K.; Ernst, T.; Maar, D.; Corner, A.; Cavo, M.
MPN-182 Droplet Digital PCR for Non-Invasive Detection of the KIT D816V Mutation in the Peripheral Blood of Patients With Suspected Systemic Mastocytosis
2022 Monaldi C.; de Santis S.; Mancini M.; Papayannidis C.; Sartor C.; Rondoni M.; Bruno S.; Cavo M.; Soverini S.
Overcoming Resistance to Kinase Inhibitors: The Paradigm of Chronic Myeloid Leukemia
2022 De Santis, S.; Monaldi, C.; Mancini, M.; Bruno, S.; Cavo, M.; Soverini, S.
Polo-like kinase-1, Aurora kinase A and WEE1 kinase are promising druggable targets in CML cells displaying BCR::ABL1-independent resistance to tyrosine kinase inhibitors
2022 Mancini M.; De Santis S.; Monaldi C.; Castagnetti F.; Lonetti A.; Bruno S.; Dan E.; Sinigaglia B.; Rosti G.; Cavo M.; Gugliotta G.; Soverini S.
Case Report: A Novel Activating FLT3 Mutation in Acute Myeloid Leukemia
2021 Bruno S.; Bandini L.; Patuelli A.; Robustelli V.; Venturi C.; Mancini M.; Forte D.; De Santis S.; Monaldi C.; Grassi A.; Chiurumbolo G.; Paolini S.; Cristiano G.; Papayannidis C.; Sartor C.; Nanni J.; Ottaviani E.; Curti A.; Cavo M.; Soverini S.
Corrigendum: Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells (Front. Oncol, (2020), 10, (1225), 10.3389/fonc.2020.01225)
2021 Salvestrini V.; Ciciarello M.; Pensato V.; Simonetti G.; Laginestra M.A.; Bruno S.; Pazzaglia M.; De Marchi E.; Forte D.; Orecchioni S.; Martinelli G.; Bertolini F.; Mendez-Ferrer S.; Adinolfi E.; Di Virgilio F.; Cavo M.; Curti A.
Distinct profile of CD34+ cells and plasma-derived extracellular vesicles from triple-negative patients with Myelofibrosis reveals potential markers of aggressive disease
2021 Forte D.; Barone M.; Morsiani C.; Simonetti G.; Fabbri F.; Bruno S.; Bandini E.; Sollazzo D.; Collura S.; Deregibus M.C.; Auteri G.; Ottaviani E.; Vianelli N.; Camussi G.; Franceschi C.; Capri M.; Palandri F.; Cavo M.; Catani L.
Integrated genomic-metabolic classification of acute myeloid leukemia defines a subgroup with NPM1 and cohesin/DNA damage mutations
2021 Simonetti G.; Mengucci C.; Padella A.; Fonzi E.; Picone G.; Delpino C.; Nanni J.; De Tommaso R.; Franchini E.; Papayannidis C.; Marconi G.; Pazzaglia M.; Perricone M.; Scarpi E.; Fontana M.C.; Bruno S.; Tebaldi M.; Ferrari A.; Bochicchio M.T.; Ghelli Luserna Di Rora A.; Ghetti M.; Napolitano R.; Astolfi A.; Baldazzi C.; Guadagnuolo V.; Ottaviani E.; Iacobucci I.; Cavo M.; Castellani G.; Haferlach T.; Remondini D.; Capozzi F.; Martinelli G.
Synthesis of Novel Tryptamine Derivatives and Their Biological Activity as Antitumor Agents
2021 Simonetti G.; Boga C.; Durante J.; Micheletti G.; Telese D.; Caruana P.; Ghelli Luserna di Rora A.; Mantellini F.; Bruno S.; Martinelli G.; Calonghi N.
Systemic mastocytosis: Molecular landscape and implications for treatment
2021 Monaldi C.; de Santis S.; Mancini M.; Bruno S.; Cavo M.; Soverini S.
Targeting leukemic stem cells in chronic myeloid leukemia: Is it worth the effort?
2021 Soverini S.; De Santis S.; Monaldi C.; Bruno S.; Mancini M.
The role of hypoxic bone marrow microenvironment in acute myeloid leukemia and future therapeutic opportunities
2021 Bruno S.; Mancini M.; De Santis S.; Monaldi C.; Cavo M.; Soverini S.
Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells
2020 Salvestrini V.; Ciciarello M.; Pensato V.; Simonetti G.; Laginestra M.A.; Bruno S.; Pazzaglia M.; De Marchi E.; Forte D.; Orecchioni S.; Martinelli G.; Bertolini F.; Mendez-Ferrer S.; Adinolfi E.; Di Virgilio F.; Cavo M.; Curti A.
Kevetrin induces apoptosis in TP53 wild-type and mutant acute myeloid leukemia cells
2020 Napolitano R.; de Matteis S.; Carloni S.; Bruno S.; Abbati G.; Capelli L.; Ghetti M.; Bochicchio M.T.; Liverani C.; Mercatali L.; Calistri D.; Cuneo A.; Menon K.; Musuraca G.; Martinelli G.; Simonetti G.
Recent advances in the molecular biology of systemic mastocytosis: Implications for diagnosis, prognosis, and therapy
2020 Martelli M.; Monaldi C.; De Santis S.; Bruno S.; Mancini M.; Cavo M.; Soverini S.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Bitter Taste Receptor Agonist Denatonium Inhibits Stemness Characteristics in Hematopoietic Stem/Progenitor Cells | Pensato V.; Laginestra M.A.; Falvo P.; Orecchioni S.; Talarico G.; De Marchi E.; Bruno S.; Mongio...rgi S.; Mitola G.; Bertolini F.; Adinolfi E.; Cavo M.; Curti A.; Salvestrini V. | 2024-01-01 | STEM CELLS | - | 1.01 Articolo in rivista | Pensato-2024_compressed.pdf |
| SETD2 non genomic loss of function in advanced systemic mastocytosis is mediated by an Aurora kinase A/MDM2 axis and can be therapeutically targeted | Mancini M.; Monaldi C.; De Santis S.; Papayannidis C.; Rondoni M.; Sartor C.; Bruno S.; Pagano L....; Criscuolo M.; Zanotti R.; Bonifacio M.; Tosi P.; Arock M.; Valent P.; Cavo M.; Soverini S. | 2023-01-01 | BIOMARKER RESEARCH | - | 1.01 Articolo in rivista | Mancini_2023.pdf; 40364_2023_468_MOESM1_ESM.docx |
| CDC20 in and out of mitosis: a prognostic factor and therapeutic target in hematological malignancies | Bruno S.; Ghelli Luserna di Rora A.; Napolitano R.; Soverini S.; Martinelli G.; Simonetti G. | 2022-01-01 | JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH | - | 1.01 Articolo in rivista | Bruno_JECCR_2022.pdf; 13046_2022_2363_MOESM1_ESM.docx |
| CML-184 A Novel Droplet Digital PCR Strategy for Rapid and Sensitive Detection of BCR::ABL1 Kinase Domain Mutations Conferring Resistance to Second-Generation Tyrosine Kinase Inhibitors | de Santis S.; Monaldi C.; Martelli M.; Mancini M.; Bruno S.; Castagnetti F.; Gugliotta G.; Polako...va K.M.; Ernst T.; Maar D.; Corner A.; Cavo M.; Soverini S. | 2022-01-01 | CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | - | 1.01 Articolo in rivista | - |
| Combined Inhibition of Polo-like Kinase-1 and Wee1 as a New Therapeutic Strategy to Induce Apoptotic Cell Death in Neoplastic Mast Cells | Mancini M.; Monaldi C.; De Santis S.; Rondoni M.; Papayannidis C.; Sartor C.; Curti A.; Bruno S.;... Cavo M.; Soverini S. | 2022-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-14-00738.pdf; cancers-14-00738-s001.zip |
| Droplet digital PCR for the detection of second-generation tyrosine kinase inhibitor-resistant BCR::ABL1 kinase domain mutations in chronic myeloid leukemia | Soverini, S.; De Santis, S.; Martelli, M.; Monaldi, C.; Castagnetti, F.; Gugliotta, G.; Papayanni...dis, C.; Mancini, M.; Bruno, S.; Venturi, C.; Machova Polakova, K.; Ernst, T.; Maar, D.; Corner, A.; Cavo, M. | 2022-01-01 | LEUKEMIA | - | 1.01 Articolo in rivista | - |
| MPN-182 Droplet Digital PCR for Non-Invasive Detection of the KIT D816V Mutation in the Peripheral Blood of Patients With Suspected Systemic Mastocytosis | Monaldi C.; de Santis S.; Mancini M.; Papayannidis C.; Sartor C.; Rondoni M.; Bruno S.; Cavo M.; ...Soverini S. | 2022-01-01 | CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | - | 1.01 Articolo in rivista | - |
| Overcoming Resistance to Kinase Inhibitors: The Paradigm of Chronic Myeloid Leukemia | De Santis, S.; Monaldi, C.; Mancini, M.; Bruno, S.; Cavo, M.; Soverini, S. | 2022-01-01 | ONCOTARGETS AND THERAPY | - | 1.01 Articolo in rivista | OTT-289306-overcoming-resistance-to-kinase-inhibitors--the-paradigm-of-.pdf |
| Polo-like kinase-1, Aurora kinase A and WEE1 kinase are promising druggable targets in CML cells displaying BCR::ABL1-independent resistance to tyrosine kinase inhibitors | Mancini M.; De Santis S.; Monaldi C.; Castagnetti F.; Lonetti A.; Bruno S.; Dan E.; Sinigaglia B....; Rosti G.; Cavo M.; Gugliotta G.; Soverini S. | 2022-01-01 | FRONTIERS IN ONCOLOGY | - | 1.01 Articolo in rivista | fonc-12-901132.pdf; file supplementari.zip |
| Case Report: A Novel Activating FLT3 Mutation in Acute Myeloid Leukemia | Bruno S.; Bandini L.; Patuelli A.; Robustelli V.; Venturi C.; Mancini M.; Forte D.; De Santis S.;... Monaldi C.; Grassi A.; Chiurumbolo G.; Paolini S.; Cristiano G.; Papayannidis C.; Sartor C.; Nanni J.; Ottaviani E.; Curti A.; Cavo M.; Soverini S. | 2021-01-01 | FRONTIERS IN ONCOLOGY | - | 1.01 Articolo in rivista | fonc-11-728613.pdf |
| Corrigendum: Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells (Front. Oncol, (2020), 10, (1225), 10.3389/fonc.2020.01225) | Salvestrini V.; Ciciarello M.; Pensato V.; Simonetti G.; Laginestra M.A.; Bruno S.; Pazzaglia M.;... De Marchi E.; Forte D.; Orecchioni S.; Martinelli G.; Bertolini F.; Mendez-Ferrer S.; Adinolfi E.; Di Virgilio F.; Cavo M.; Curti A. | 2021-01-01 | FRONTIERS IN ONCOLOGY | - | 1.01 Articolo in rivista | fonc-11-668460 (1).pdf |
| Distinct profile of CD34+ cells and plasma-derived extracellular vesicles from triple-negative patients with Myelofibrosis reveals potential markers of aggressive disease | Forte D.; Barone M.; Morsiani C.; Simonetti G.; Fabbri F.; Bruno S.; Bandini E.; Sollazzo D.; Col...lura S.; Deregibus M.C.; Auteri G.; Ottaviani E.; Vianelli N.; Camussi G.; Franceschi C.; Capri M.; Palandri F.; Cavo M.; Catani L. | 2021-01-01 | JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH | - | 1.01 Articolo in rivista | s13046-020-01776-8.pdf; 13046_2020_1776_MOESM1_ESM.pdf |
| Integrated genomic-metabolic classification of acute myeloid leukemia defines a subgroup with NPM1 and cohesin/DNA damage mutations | Simonetti G.; Mengucci C.; Padella A.; Fonzi E.; Picone G.; Delpino C.; Nanni J.; De Tommaso R.; ...Franchini E.; Papayannidis C.; Marconi G.; Pazzaglia M.; Perricone M.; Scarpi E.; Fontana M.C.; Bruno S.; Tebaldi M.; Ferrari A.; Bochicchio M.T.; Ghelli Luserna Di Rora A.; Ghetti M.; Napolitano R.; Astolfi A.; Baldazzi C.; Guadagnuolo V.; Ottaviani E.; Iacobucci I.; Cavo M.; Castellani G.; Haferlach T.; Remondini D.; Capozzi F.; Martinelli G. | 2021-01-01 | LEUKEMIA | - | 1.01 Articolo in rivista | s41375-021-01318-x.pdf |
| Synthesis of Novel Tryptamine Derivatives and Their Biological Activity as Antitumor Agents | Simonetti G.; Boga C.; Durante J.; Micheletti G.; Telese D.; Caruana P.; Ghelli Luserna di Rora A....; Mantellini F.; Bruno S.; Martinelli G.; Calonghi N. | 2021-01-01 | MOLECULES | - | 1.01 Articolo in rivista | molecules-26-00683 (1).pdf |
| Systemic mastocytosis: Molecular landscape and implications for treatment | Monaldi C.; de Santis S.; Mancini M.; Bruno S.; Cavo M.; Soverini S. | 2021-01-01 | MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES | - | 1.01 Articolo in rivista | mjhid-13-1-e2021046.pdf |
| Targeting leukemic stem cells in chronic myeloid leukemia: Is it worth the effort? | Soverini S.; De Santis S.; Monaldi C.; Bruno S.; Mancini M. | 2021-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-22-07093-v2.pdf |
| The role of hypoxic bone marrow microenvironment in acute myeloid leukemia and future therapeutic opportunities | Bruno S.; Mancini M.; De Santis S.; Monaldi C.; Cavo M.; Soverini S. | 2021-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-22-06857-v2.pdf |
| Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells | Salvestrini V.; Ciciarello M.; Pensato V.; Simonetti G.; Laginestra M.A.; Bruno S.; Pazzaglia M.;... De Marchi E.; Forte D.; Orecchioni S.; Martinelli G.; Bertolini F.; Mendez-Ferrer S.; Adinolfi E.; Di Virgilio F.; Cavo M.; Curti A. | 2020-01-01 | FRONTIERS IN ONCOLOGY | - | 1.01 Articolo in rivista | Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells.pdf; 5072249.zip |
| Kevetrin induces apoptosis in TP53 wild-type and mutant acute myeloid leukemia cells | Napolitano R.; de Matteis S.; Carloni S.; Bruno S.; Abbati G.; Capelli L.; Ghetti M.; Bochicchio ...M.T.; Liverani C.; Mercatali L.; Calistri D.; Cuneo A.; Menon K.; Musuraca G.; Martinelli G.; Simonetti G. | 2020-01-01 | ONCOLOGY REPORTS | - | 1.01 Articolo in rivista | or-44-04-1561.pdf; Supplementary_Data.pdf |
| Recent advances in the molecular biology of systemic mastocytosis: Implications for diagnosis, prognosis, and therapy | Martelli M.; Monaldi C.; De Santis S.; Bruno S.; Mancini M.; Cavo M.; Soverini S. | 2020-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | Martelli_ijms_2020.pdf |