MENOTTI, LAURA
MENOTTI, LAURA
DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Docenti di ruolo di IIa fascia
A heptad repeat in herpes simplex virus-1 gH, located downstream of the α-helix with attributes of a fusion peptide, is critical for virus entry and fusion.
2005 GIANNI T.; MENOTTI L.; CAMPADELLI-FIUME G.
A herpes simplex virus recombinant that exhibits a single-chain antibody to HER2/neu enters cells through the mammary tumor receptor, independently of the gD receptors.
2006 Menotti L.; Cerretani A.; Campadelli-Fiume G.
A murine model for virotherapy of malignant brain tumors.
2011 Gambini E.; Reisoli E.; Appolloni I.; Menotti L.; Malatesta P.
Cell-to-cell spread of wild-type herpes simplex virus type 1, but not of syncytial strains, is mediated by the immunoglobulin-like receptors that mediate virion entry, Nectin1 (PRR1/HveC/HIgR) and Nectin2 (PRR2/HveB)
2000 Cocchi F.; Menotti L.; Dubreuil P.; Lopez M.; Campadelli-Fiume G.
Chimeric nectin1-poliovirus receptor molecules identify a nectin1 region functional in herpes simplex virus entry
2001 Cocchi F.; Lopez M.; Dubreuil P.; Campadelli Fiume G.; Menotti L.
Comparison of murine and human nectin1 binding to herpes simplex virus glycoprotein D (gD) reveals a weak interaction of murine nectin1 to gD and a gD-dependent pathway of entry
2001 Menotti L.; Avitabile E.; Dubreuil P.; Lopez M.; Campadelli-Fiume G.
Construction of a fully retargeted herpes simplex virus 1 recombinant capable of entering cells solely via human epidermal growth factor receptor 2
2008 Menotti L.; Cerretani A.; Hengel H.; Campadelli-Fiume G.
Critical residues in the CC′ ridge of the human nectin1 receptor V domain enable herpes simplex virus entry into the cell and act synergistically with the downstream region
2002 Menotti L.; Cocchi F.; Campadelli-Fiume G.
Efficacy of HER2 retargeted herpes simplex virus as therapy for high-grade glioma in immunocompetent mice.
2012 Reisoli E.; Gambini E.; Appolloni I.; Gatta V.; Barilari M.; Menotti L.; Malatesta P.
Entry of alphaherpesviruses into the cell
2007 G. Campadelli-Fiume; L. Menotti
Entry of herpes simplex virus mediated by chimeric forms of nectin1 retargeted to endosomes or to lipid rafts occurs through acidic endosomes.
2004 GIANNI T.; CAMPADELLI-FIUME G.; MENOTTI L.
Eradication of glioblastoma by immuno-virotherapy with a retargeted oncolytic HSV in a preclinical model
2019 Alessandrini, Francesco; Menotti, Laura; Avitabile, Elisa; Appolloni, Irene; Ceresa, Davide; Marubbi, Daniela; Campadelli-Fiume, Gabriella; Malatesta, Paolo
Herpes simplex virus (HSV) with modified tropism, uses and process of preparation thereof.
2008 Campadelli-Fiume G.; Menotti L.
Herpes simplex virus oncolytic immunovirotherapy: The blossoming branch of multimodal therapy
2020 Menotti L.; Avitabile E.
Herpesviruses as oncolytic agents
2012 Campadelli-Fiume G.; Menotti L.; Zhou G.; De Giovanni C.; Nanni P.; Lollini P.-L.
HSV as A Platform for the Generation of Retargeted, Armed, and Reporter-Expressing Oncolytic Viruses
2018 Menotti, Laura; Avitabile, Elisa; Gatta, Valentina; Malatesta, Paolo; Petrovic, Biljana; Campadelli-Fiume, Gabriella
Human herpesvirus 6: An emerging pathogen
1999 Campadelli-Fiume G.; Mirandola P.; Menotti L.
Inhibition of human tumor growth in mice by an oncolytic herpes simplex virus designed to target solely HER-2-positive cells.
2009 Menotti L.; Nicoletti G.; Gatta V.; Croci S.; Landuzzi L.; De Giovanni C.; Nanni P.; Lollini P.L.; Campadelli-Fiume G.
MODIFICAZIONE DEL TROPISMO DEL VIRUS HERPES SIMPLEX VERSO RECETTORI SELEZIONATI
2005 Campadelli-Fiume G.; Menotti L.
Nectin2α (PRR2α or HveB) and nectin2δ are low-efficiency mediators for entry of herpes simplex virus mutants carrying the Leu25Pro substitution in glycoprotein D
2000 Lopez M.; Cocchi F.; Menotti L.; Avitabile E.; Dubreuil P.; Campadelli-Fiume G.