ROBERTI, MARINELLA

ROBERTI, MARINELLA  

DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE  

Docenti di ruolo di IIa fascia  

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Risultati 1 - 20 di 80 (tempo di esecuzione: 0.037 secondi).
Titolo Autore(i) Anno Periodico Editore Tipo File
A journey through targeting BRCA2-RAD51 protein-protein interaction to establish synthetic lethality as paradigm for anticancer drug discovery Bagnolini G., Poppi L., Previtali V., Ferrandi G., Rinaldi F., Girotto S., Hirsch A.K.H., Roberti... M., Cavalli A. 2024-01-01 - - 4.01 Contributo in Atti di convegno -
A RAD51/BRCA2 small molecule inhibitor enhances the antineoplastic effect of the PARPi talazoparib in pancreatic cancer Laura Poppi, Samuel H Myers, Viola Previtali, Francesco Rinaldi, Fulvia Farabegoli, Giuseppina Di... Stefano, Naomi Walsh, Marinella Roberti, Andrea Cavalli 2023-01-01 - FEBS PRESS 4.03 Poster -
An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer Myers S. H., Poppi L., Rinaldi F., Veronesi M., Ciamarone A., Previtali V., Bagnolini G., Schipan...i F., Ortega Martínez J. A., Girotto S., Di Stefano G., Farabegoli F., Walsh N., De Franco F., Roberti M., Cavalli A. 2023-01-01 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 1.01 Articolo in rivista AN19FN~1.PDF1-s2.0-S0223523423010814-mmc1.docx
Application of an “inhalation by design” approach to the identification and in-vitro evaluation of novel purine based PI3Kδ inhibitors Mazzucato R.; Roberti M.; Capelli A.M.; Rancati F.; Biagetti M.; Fiorelli C.; Bruno P.; Ronchi P....; Bertolini S.; Corsi M.; Pala D. 2023-01-01 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 1.01 Articolo in rivista -
Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5 Brusa, Irene; Sondo, Elvira; Pesce, Emanuela; Tomati, Valeria; Gioia, Dario; Falchi, Federico; Ba...lboni, Beatrice; Ortega Martínez, Jose Antonio; Veronesi, Marina; Romeo, Elisa; Margaroli, Natasha; Recanatini, Maurizio; Girotto, Stefania; Pedemonte, Nicoletta; Roberti, Marinella; Cavalli, Andrea 2023-01-01 JOURNAL OF MEDICINAL CHEMISTRY - 1.01 Articolo in rivista brusa-et-al-2023-innovative-strategy-toward-mutant-cftr-rescue-in-cystic-fibrosis-design-and-synthesis-of-thiadiazole.pdf
Preomic profile of BxPC-3 cells after treatment with BRC4 Previtali V.; Myers S.H.; Poppi L.; Wynne K.; Casamassima I.; Girotto S.; Di Stefano G.; Farabego...li F.; Roberti M.; Oliviero G.; Cavalli A. 2023-01-01 JOURNAL OF PROTEOMICS - 1.01 Articolo in rivista -
Proteomic profile of BxPC-3 cells after treatment with BRC4 Viola Previtali, Samuel H. Myers, Laura Poppi, Kieran Wynne, Irene Casamassima Stefania Girotto, ...Giuseppina Di Stefano, Fulvia Farabegoli, Marinella Roberti, Giorgio Oliviero, Andrea Cavalli 2023-01-01 JOURNAL OF PROTEOMICS - 1.01 Articolo in rivista -
Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One Salerno, Alessandra; Seghetti, Francesca; Caciolla, Jessica; Uliassi, Elisa; Testi, Eleonora; Gua...rdigni, Melissa; Roberti, Marinella; Milelli, Andrea; Bolognesi, Maria Laura 2022-01-01 JOURNAL OF MEDICINAL CHEMISTRY - 1.01 Articolo in rivista acs.jmedchem.2c00302.pdf
Identification and subsequent development of RAD51-BRCA2 disruptors through a fragment-based approach Samuel Harry Myers , Viola Previtali, Laura Poppi, Francesco Rinaldi, Fabrizio Schipani, Jose Ant...onio Ortega, Francesca De Franco, Marina Veronesi, Roberto Pellicciari, Marinella Roberti, Stefania Girotto, Giuseppina Di Stefano, Andrea Cavalli 2022-01-01 - - 4.02 Riassunto (Abstract) -
Identification of RAD51-BRCA2 Inhibitors Using N-Acylhydrazone-Based Dynamic Combinatorial Chemistry Bagnolini, G.; Balboni, B.; Schipani, F.; Gioia, D.; Veronesi, M.; De Franco, F.; Kaya, C.; Jumde..., R. P.; Ortega, J. A.; Girotto, S.; Hirsch, A. K. H.; Roberti, M.; Cavalli, A. 2022-01-01 ACS MEDICINAL CHEMISTRY LETTERS - 1.01 Articolo in rivista acsmedchemlett._2022.pdf
Insights into the activity of ARN24089, a new RAD51-BRCA2 disruptor that inhibits homologous recombination and achieves synthetic lethality in pancreatic cancer Previtali V., Myers S. H., Bagnolini G., Poppi L., Rinaldi F., Schipani F., Ortega J. A., De Fran...co F., Pellicciari R., Girotto S., Oliviero G., Walsh N., Valenti G., Tirelli N., Di Stefano G., Roberti M., Cavalli A. 2022-01-01 - - 4.02 Riassunto (Abstract) -
Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives Brusa I.; Sondo E.; Falchi F.; Pedemonte N.; Roberti M.; Cavalli A. 2022-01-01 JOURNAL OF MEDICINAL CHEMISTRY - 1.01 Articolo in rivista acs.jmedchem.1c01897.pdf
The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination Schipani, Fabrizio; Manerba, Marcella; Marotta, Roberto; Poppi, Laura; Gennari, Arianna; Rinaldi,... Francesco; Armirotti, Andrea; Farabegoli, Fulvia; Roberti, Marinella; Di Stefano, Giuseppina; Rocchia, Walter; Girotto, Stefania; Tirelli, Nicola; Cavalli, Andrea 2022-01-01 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 1.01 Articolo in rivista ijms-23-08338-v3 (1).pdf
Antiparasitic effect of stilbene and terphenyl compounds against trypanosoma cruzi parasites Bruno F.; Castelli G.; Vitale F.; Catanzaro S.; Badaco V.V.; Roberti M.; Colomba C.; Cascio A.; T...olomeo M. 2021-01-01 PHARMACEUTICALS - 1.01 Articolo in rivista pharmaceuticals 2020.pdf
Inhibition of Urease, a Ni-Enzyme: The Reactivity of a Key Thiol With Mono- and Di-Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies Mazzei L.; Contaldo U.; Musiani F.; Cianci M.; Bagnolini G.; Roberti M.; Ciurli S. 2021-01-01 ANGEWANDTE CHEMIE. INTERNATIONAL EDITION - 1.01 Articolo in rivista Manuscript.pdfSupplementary Information.pdf
Lactate dehydrogenase inhibition affects homologous recombination repair independently of cell metabolic asset; implications for anticancer treatment Balboni A.; Govoni M.; Rossi V.; Roberti M.; Cavalli A.; Di Stefano G.; Manerba M. 2021-01-01 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS - 1.01 Articolo in rivista -
RAD51 nuclear recruitment and inhibition towards innovative strategies against pancreatic cancer Schipani, Fabrizio; Manerba, Marcella; Marotta, Roberto; Gennari, Arianna; Rinaldi, Francesco; Ar...mirotti, Andrea; Roberti, Marinella; Di Stefano, Giuseppina; Rocchia, Walter; Tirelli, Nicola; Girotto, Stefania; Cavalli, Andrea 2021-01-01 bioRxiv - 1.01 Articolo in rivista -
Free-radical-mediated formation of trans-cardiolipin isomers, analytical approaches for lipidomics and consequences of the structural organization of membranes Vetica F.; Sansone A.; Meliota C.; Batani G.; Roberti M.; Chatgilialoglu C.; Ferreri C. 2020-01-01 BIOMOLECULES - 1.01 Articolo in rivista biomolecules-10-01189 (1).pdf
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign Linciano P.; Cullia G.; Borsari C.; Santucci M.; Ferrari S.; Witt G.; Gul S.; Kuzikov M.; Ellinge...r B.; Santarem N.; Cordeiro da Silva A.; Conti P.; Bolognesi M.L.; Roberti M.; Prati F.; Bartoccini F.; Retini M.; Piersanti G.; Cavalli A.; Goldoni L.; Bertozzi S.M.; Bertozzi F.; Brambilla E.; Rizzo V.; Piomelli D.; Pinto A.; Bandiera T.; Costi M.P. 2020-01-01 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 1.01 Articolo in rivista -
Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib Bagnolini G.; Milano D.; Manerba M.; Schipani F.; Ortega J.A.; Gioia D.; Falchi F.; Balboni A.; F...arabegoli F.; De Franco F.; Robertson J.; Pellicciari R.; Pallavicini I.; Peri S.; Minucci S.; Girotto S.; Di Stefano G.; Roberti M.; Cavalli A. 2020-01-01 JOURNAL OF MEDICINAL CHEMISTRY - 1.01 Articolo in rivista ASAP_acs.jmedchem.9b01526.pdf