HOCHKOEPPLER, ALEJANDRO
HOCHKOEPPLER, ALEJANDRO
FABIT - DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Docenti di ruolo di IIa fascia
The catalytic action of enzymes exposed to charged substrates outperforms the activity exerted on their neutral counterparts
2025 Stefan, A.; Hochkoeppler, A.
Lactate-Induced HBEGF Shedding and EGFR Activation: Paving the Way to a New Anticancer Therapeutic Opportunity
2024 Rossi, V.; Hochkoeppler, A.; Govoni, M.; Di Stefano, G.
Peptides inhibiting the assembly of monomeric human l‐lactate dehydrogenase into catalytically active homotetramer decrease the synthesis of lactate in cultured cells
2024 Stefan, Alessandra; Gentilucci, Luca; Ruffolo, Francesca; Rossi, Valentina; Sordi, Sofia; He, Tingting; di Stefano, Giuseppina; Santino, Federica; Brigotti, Maurizio; Scotti, Claudia; Iamele, Luisa; de Jonge, Hugo; Piaz, Fabrizio Dal; Santarcangelo, Danilo Rocco; Hochkoeppler, Alejandro
The catalytic action of human D-lactate dehydrogenase is severely inhibited by oxalate and is impaired by mutations triggering D-lactate acidosis
2024 Stefan, A.; Mucchi, A.; Hochkoeppler, A.
The four subunits of rabbit skeletal muscle lactate dehydrogenase do not exert their catalytic action additively
2024 Rossi M.; Tomaselli F.; Hochkoeppler A.
Amberlite XAD-4 is a convenient tool for removing Triton X-100 and Sarkosyl from protein solutions
2023 Scutteri L.; Maltoni G.; Hochkoeppler A.
The Mycobacterium tuberculosis protein tyrosine phosphatase MptpA features a pH dependent activity overlapping the bacterium sensitivity to acidic conditions
2023 Kovermann M.; Stefan A.; Palazzetti C.; Immler F.; Dal Piaz F.; Bernardi L.; Cimone V.; Bellone M.L.; Hochkoeppler A.
Trehalose counteracts the dissociation of tetrameric rabbit lactate dehydrogenase induced by acidic pH conditions
2023 Simongini M.; Puglisi A.; Genovese F.; Hochkoeppler A.
Tyrosine inhibits the Mycobacterium tuberculosis protein tyrosine phosphatase MptpA
2023 Alessandra Stefan; Chiara Palazzetti; Alejandro Hochkoeppler
Allosteric transitions of rabbit skeletal muscle lactate dehydrogenase induced by pH-dependent dissociation of the tetrameric enzyme
2022 Iacovino, L. G.; Rossi, M.; Di Stefano, G.; Rossi, V.; Binda, C.; Brigotti, M.; Tomaselli, F.; Pasti, A. P.; Dal Piaz, F.; Cerini, S.; Hochkoeppler, A.
High-yield production in Escherichia coli and convenient purification of a candidate vaccine against SARS-CoV-2
2022 Maltoni G.; Scutteri L.; Mensitieri F.; Piaz F.D.; Hochkoeppler A.
Human lactate dehydrogenase A undergoes allosteric transitions under pH conditions inducing the dissociation of the tetrameric enzyme
2022 Pasti A.P.; Rossi V.; Di Stefano G.; Brigotti M.; Hochkoeppler A.
ASFV DNA polymerase extends recessed DNAs with catalytic efficiencies outperforming those exerted on gapped DNA substrates
2021 Lapenna A.; Stefan A.; Hochkoeppler A.
Production in Escherichia coli of recombinant COVID-19 spike protein fragments fused to CRM197
2021 Bellone M.L.; Puglisi A.; Dal Piaz F.; Hochkoeppler A.
Antibacterial activity of a new class of tris homoleptic Ru (II)-complexes with alkyl-tetrazoles as diimine-type ligands
2020 Monti N.; Zacchini S.; Massi M.; Hochkoeppler A.; Giorgini L.; Fiorini V.; Stefan A.; Stagni S.
Purification from Deinococcus radiodurans of a 66 kDa ABC transporter acting on peptides containing at least 3 amino acids
2020 Stefan A.; Gentilucci L.; Piaz F.D.; D'Alessio F.; Santino F.; Hochkoeppler A.
Substrate Activation of the Low-Molecular Weight Protein Tyrosine Phosphatase from Mycobacterium tuberculosis
2020 Stefan A.; Dal Piaz F.; Girella A.; Hochkoeppler A.
Synthesis and Photochemical Properties of Manganese(I) Tricarbonyl Diimine Complexes Bound to Tetrazolato Ligands
2020 Stout M.J.; Stefan A.; Skelton B.W.; Sobolev A.N.; Massi M.; Hochkoeppler A.; Stagni S.; Simpson P.V.
Structural and catalytic insights into HoLaMa, a derivative of Klenow DNA polymerase lacking the proofreading domain
2019 Kovermann M.; Stefan A.; Castaldo A.; Caramia S.; Hochkoeppler A.
Luminescent protein staining with Re(i) tetrazolato complexes
2018 Fiorini, Valentina*; Bergamini, Linda; Monti, Nicola; Zacchini, Stefano; Plush, Sally E.; Massi, Massimiliano; Hochkoeppler, Alejandro; Stefan, Alessandra; Stagni, Stefano