RAMBALDI, MIRELLA
RAMBALDI, MIRELLA
ARAG - AREA FINANZA E CONTABILITA'
Collaboratori
Synthesis of 3-(Imidazo[2,1-b]thiazol-6-yl)-2H-chromen-2-one derivatives and study of their antiviral activity against parvovirus B19
2019 Conti, Ilaria; Morigi, Rita; Locatelli, Alessandra*; Rambaldi, Mirella; Bua, Gloria; Gallinella, Giorgio; Leoni, Alberto
Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents
2019 Morigi, R., Locatelli, A., Leoni, A., Rambaldi, M., Bortolozzi, R., Mattiuzzo, E., Ronca, R., Maccarinelli, F., Hamel, E., Bai, R., Brancale, A., Viola, G.
Investigation on the effects of antimicrobial imidazo[2,1-b]thiazole derivatives on the genitourinary microflora
2018 Morigi, Rita; Vitali, Beatrice; Prata, Cecilia; Palomino, Rogers A. A; Graziadio, Alessandra; Locatelli, Alessandra; Rambaldi, Mirella; Leoni, Alberto
Targeting human telomeric and promoter G-quardruplexes: synthesis, biophysical and biological studies of new guanylhydrazones as potential antitumor agents
2018 R. Morigi, J. Amato, N. Iaccarino, B. Pagano, A. Locatelli, A. Leoni, M. Rambaldi, G. Miglietta, J. Marinello, G. Capranico, E. Novellino, A. Randazzo
A Patent Review on Thiazole Derivatives (2008-2013)
2017 Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella
G-quadruplex binders cause DNA damage by inducing R loops in human cancer cells.
2017 A. De Magis, S. G. Manzo, J. Marinello, R. Morigi, M. Rambaldi, O. Sodet, G. Capranico.
Imidazo[2,1-b] Thiazole: Introduction, Current and Perspective
2017 Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella
Toward the development of specific G-quadruplex binders: biophysical studies of new hydrazone derivatives.
2017 N. Iaccarino, J. Amato, R. Morigi, A. Pagano, A. De Magis, G. Capranico, A. Locatelli, A. Graziadio, A. Leoni, M. Rambaldi, E. Novellino, S. Neidle, B. Pagano, A. Randazzo.
2-Indolinone a versatile scaffold for treatment of cancer: A patent review (2008-2014)
2016 Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella
Small-Molecules Targeting Kinases Involved in Pulmonary Hypertension: a Patent Review (2010-2015)
2016 Morigi, Rita; Rambaldi, Mirella; Locatelli, Alessandra; Leoni, Alberto
Small-Molecules Targeting Sirtuin 1: A Patent Review (2012-2015)
2016 Graziadio, Alessandra; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella
Toward the Development of Specific G‑Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives
2016 Amato, Jussara; Morigi, Rita; Pagano, Bruno; Pagano, Alessia; Ohnmacht, Stephan; De Magis Alessio; Tiang, Yee-Peng; Capranico, Giovanni; Locatelli, Alessandra; Graziadio, Alessandra; Leoni, Alberto; Rambaldi, Mirella; Novellino, Ettore; Neidle, Stephen; Randazzo, Antonio
An Unexpected Pathway to Enantiomerization of Hemithioketals in Toluene Involving a Dimeric Transition State: A Combined Experimental and Computational Study
2015 Bottoni, Andrea; Calvaresi, Matteo; Cosimelli, Barbara; Mazzanti, Andrea; Rambaldi, Mirella; Spinelli, Domenico
P53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells
2015 Cappadone, C; Stefanelli, C.; Malucelli, E.; Zini, M.; Onofrillo, C.; Locatelli, A.; Rambaldi, M.; Sargenti, A.; Merolle, L.; Farruggia, G.; Graziadio, A.; Montanaro, L.; Iotti, S.
p53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells
2015 Graziadio, Alessandra; Locatelli, Alessandra; Leoni, Alberto; Morigi, Rita; Rambaldi, Mirella; Cappadone, Concettina; Merolle, Lucia; Sargenti, Azzurra
Recent Patents on Thiazole Derivatives Endowed with Antitumor Activity
2015 Morigi Rita; Locatelli Alessandra; Leoni Alberto; Mirella Rambaldi
Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplex.
2014 Jussara Amato; Nunzia Iaccarino; Bruno Pagano; Rita Morigi; Alessandra Locatelli; Alberto Leoni; Mirella Rambaldi; Pasquale Zizza; Annamaria Biroccio; Ettore Novellino; Antonio Randazzo
Identification of a new benzoindol-2-one derivative as a potential modulator of p53 pathway in cancer cells
2014 Graziadio A.; Locatelli A.; Leoni A.; Morigi R.; Rambaldi M.; Cappadone C.; Merolle L.; Sargenti A.
Novel thiazole derivatives: a patent review (2008 – 2012; Part 1)
2014 Alberto Leoni;Alessandra Locatelli;Rita Morigi;Mirella Rambaldi
Novel thiazole derivatives: a patent review (2008-2012. Part.2)
2014 Alberto Leoni; Alessandra Locatelli; Rita Morigi; Mirella Rambaldi
Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
---|---|---|---|---|---|---|
Synthesis of 3-(Imidazo[2,1-b]thiazol-6-yl)-2H-chromen-2-one derivatives and study of their antiviral activity against parvovirus B19 | Conti, Ilaria; Morigi, Rita; Locatelli, Alessandra*; Rambaldi, Mirella; Bua, Gloria; Gallinella, ...Giorgio; Leoni, Alberto | 2019-01-01 | MOLECULES | - | 1.01 Articolo in rivista | molecules-24-01037.pdf |
Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents | Morigi, R., Locatelli, A., Leoni, A., Rambaldi, M., Bortolozzi, R., Mattiuzzo, E., Ronca, R., Mac...carinelli, F., Hamel, E., Bai, R., Brancale, A., Viola, G. | 2019-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | EJMC 166, 2019, 514 530 Post print .pdf |
Investigation on the effects of antimicrobial imidazo[2,1-b]thiazole derivatives on the genitourinary microflora | Morigi, Rita; Vitali, Beatrice; Prata, Cecilia; Palomino, Rogers A. A; Graziadio, Alessandra; Loc...atelli, Alessandra; Rambaldi, Mirella; Leoni, Alberto | 2018-01-01 | MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Targeting human telomeric and promoter G-quardruplexes: synthesis, biophysical and biological studies of new guanylhydrazones as potential antitumor agents | R. Morigi, J. Amato, N. Iaccarino, B. Pagano, A. Locatelli, A. Leoni, M. Rambaldi, G. Miglietta, ...J. Marinello, G. Capranico, E. Novellino, A. Randazzo | 2018-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
A Patent Review on Thiazole Derivatives (2008-2013) | Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella | 2017-01-01 | ACTA CHIMICA & PHARMACEUTICA INDICA | - | 1.01 Articolo in rivista | - |
G-quadruplex binders cause DNA damage by inducing R loops in human cancer cells. | A. De Magis, S. G. Manzo, J. Marinello, R. Morigi, M. Rambaldi, O. Sodet, G. Capranico. | 2017-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
Imidazo[2,1-b] Thiazole: Introduction, Current and Perspective | Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella | 2017-01-01 | BIOENERGETICS | - | 1.01 Articolo in rivista | - |
Toward the development of specific G-quadruplex binders: biophysical studies of new hydrazone derivatives. | N. Iaccarino, J. Amato, R. Morigi, A. Pagano, A. De Magis, G. Capranico, A. Locatelli, A. Graziad...io, A. Leoni, M. Rambaldi, E. Novellino, S. Neidle, B. Pagano, A. Randazzo. | 2017-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
2-Indolinone a versatile scaffold for treatment of cancer: A patent review (2008-2014) | Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella | 2016-01-01 | EXPERT OPINION ON THERAPEUTIC PATENTS | - | 1.01 Articolo in rivista | - |
Small-Molecules Targeting Kinases Involved in Pulmonary Hypertension: a Patent Review (2010-2015) | Morigi, Rita; Rambaldi, Mirella; Locatelli, Alessandra; Leoni, Alberto | 2016-01-01 | CURRENT MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Small-Molecules Targeting Sirtuin 1: A Patent Review (2012-2015) | Graziadio, Alessandra; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella | 2016-01-01 | MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Toward the Development of Specific G‑Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives | Amato, Jussara; Morigi, Rita; Pagano, Bruno; Pagano, Alessia; Ohnmacht, Stephan; De Magis Alessio...; Tiang, Yee-Peng; Capranico, Giovanni; Locatelli, Alessandra; Graziadio, Alessandra; Leoni, Alberto; Rambaldi, Mirella; Novellino, Ettore; Neidle, Stephen; Randazzo, Antonio | 2016-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | J Med Chem, 2016, 59 (12), 5706–5720 post print(3).pdf |
An Unexpected Pathway to Enantiomerization of Hemithioketals in Toluene Involving a Dimeric Transition State: A Combined Experimental and Computational Study | Bottoni, Andrea; Calvaresi, Matteo; Cosimelli, Barbara; Mazzanti, Andrea; Rambaldi, Mirella; Spin...elli, Domenico | 2015-01-01 | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | - | 1.01 Articolo in rivista | - |
P53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells | Cappadone, C; Stefanelli, C.; Malucelli, E.; Zini, M.; Onofrillo, C.; Locatelli, A.; Rambaldi, M....; Sargenti, A.; Merolle, L.; Farruggia, G.; Graziadio, A.; Montanaro, L.; Iotti, S. | 2015-01-01 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | - | 1.01 Articolo in rivista | - |
p53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells | Graziadio, Alessandra; Locatelli, Alessandra; Leoni, Alberto; Morigi, Rita; Rambaldi, Mirella; Ca...ppadone, Concettina; Merolle, Lucia; Sargenti, Azzurra | 2015-01-01 | - | Società Chimica Italiana | 4.02 Riassunto (Abstract) | - |
Recent Patents on Thiazole Derivatives Endowed with Antitumor Activity | Morigi Rita; Locatelli Alessandra; Leoni Alberto; Mirella Rambaldi | 2015-01-01 | RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY | - | 1.01 Articolo in rivista | - |
Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplex. |
Jussara Amato; Nunzia Iaccarino; Bruno Pagano; Rita Morigi; Alessandra Locatelli; Alberto Leoni;... Mirella Rambaldi; Pasquale Zizza; Annamaria Biroccio; Ettore Novellino; Antonio Randazzo |
2014-01-01 | FRONTIERS IN CHEMISTRY | - | 1.01 Articolo in rivista | - |
Identification of a new benzoindol-2-one derivative as a potential modulator of p53 pathway in cancer cells | Graziadio A.; Locatelli A.; Leoni A.; Morigi R.; Rambaldi M.; Cappadone C.; Merolle L.; Sargenti A. | 2014-01-01 | - | SCI | 4.02 Riassunto (Abstract) | - |
Novel thiazole derivatives: a patent review (2008 – 2012; Part 1) | Alberto Leoni;Alessandra Locatelli;Rita Morigi;Mirella Rambaldi | 2014-01-01 | EXPERT OPINION ON THERAPEUTIC PATENTS | - | 1.01 Articolo in rivista | - |
Novel thiazole derivatives: a patent review (2008-2012. Part.2) | Alberto Leoni; Alessandra Locatelli; Rita Morigi; Mirella Rambaldi | 2014-01-01 | EXPERT OPINION ON THERAPEUTIC PATENTS | - | 1.01 Articolo in rivista | - |