TRAZZI, STEFANIA
TRAZZI, STEFANIA
DIPARTIMENTO DI SCIENZE BIOMEDICHE E NEUROMOTORIE
Ricercatori a tempo determinato
Age-related cognitive and motor decline in a mouse model of CDKL5 deficiency disorder is associated with increased neuronal senescence and death
2021-01-01 Gennaccaro L.; Fuchs C.; Loi M.; Pizzo R.; Alvente S.; Berteotti C.; Lupori L.; Sagona G.; Galvani G.; Gurgone A.; Raspanti A.; Medici G.; Tassinari M.; Trazzi S.; Ren E.; Rimondini R.; Pizzorusso T.; Zoccoli G.; Giustetto M.; Ciani E.
Age-related impairment of olfactory bulb neurogenesis in the Ts65Dn mouse model of Down syndrome
2014-01-01 Bianchi P; Bettini S; Guidi S; Ciani E; Trazzi S; Stagni F; Ragazzi E; Franceschini V; Bartesaghi R.
APP-dependent alteration of GSK3β activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome.
2014-01-01 Trazzi S;Fuchs C;De Franceschi M;Mitrugno VM;Bartesaghi R;Ciani E
APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.
2011-01-01 Trazzi S.; Mitrugno V.M.; Valli E.; Fuchs C.; Rizzi S.; Guidi S.; Perini G.; Bartesaghi R.; Ciani E.
The C-Terminal Domain of CENP-C Displays Multiple and Critical Functions for Mammalian Centromere Formation.
2009-01-01 Trazzi S.; Perini G.; Bernardoni R.; Zoli M.; Reese J. C.; Musacchio A.; Della Valle G.
CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/GSK-3{beta}/{beta}-catenin signaling
2010-01-01 TRAZZI S.; STEGER M.; MITRUGNO V.M.; BARTESAGHI R.;CIANI E.
CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling (vol 29, pg 658, 2019)
2019-01-01 Fuchs C.; Medici G.; Trazzi S.; Gennaccaro L.; Galvani G.; Berteotti C.; Ren E.; Loi M.; Ciani E.
CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder
2018-01-01 Trazzi, Stefania; De Franceschi, Marianna; Fuchs, Claudia; Bastianini, Stefano; Viggiano, Rocchina; Lupori, Leonardo; Mazziotti, Raffaele; Medici, Giorgio; Martire, Viviana Lo; Ren, Elisa; Rimondini, Roberto; Zoccoli, Giovanna; Bartesaghi, Renata; Pizzorusso, Tommaso; Ciani, Elisabetta*
CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells
2012-01-01 VALLI E; TRAZZI S; FUCHS C; ERRIQUEZ D; BARTESAGHI R; PERINI G; CIANI E
CENP-C binds the alpha-satellite DNA in vivo at specific centromere domains
2004-01-01 Politi, V; Perini, G; Trazzi, S; Pliss, A; Raska, I; Earnshaw, Wc; Della Valle, G
DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions
2009-01-01 Gopalakrishnan S.; Sullivan B. A.; Trazzi S.; Della Valle G.; Robertson K. D.
Early Pharmacotherapy Restores Neurogenesis and Cognitive Performance in the Ts65Dn Mouse Model for Down Syndrome
2010-01-01 P. Bianchi; E. Ciani; S. Guidi; S. Trazzi; D. Felice; G. Grossi; M. Fernandez; A. Giuliani; L. Calza'; R. Bartesaghi
Early Pharmacotherapy with Fluoxetine Rescues Dendritic Pathology in the Ts65Dn Mouse Model of Down Syndrome
2013-01-01 Sandra Guidi;Fiorenza Stagni;Patrizia Bianchi;Elisabetta Ciani;Elena Ragazzi;Stefania Trazzi;Gabriele Grossi;Chiara Mangano;Laura Calzà;Renata Bartesaghi
Early-occurring proliferation defects in peripheral tissues of the Ts65Dn mouse model of Down syndrome are associated with patched1 over expression
2012-01-01 Fuchs C; Ciani E; Guidi S; Trazzi S; Bartesaghi R
Expression of a Secretable, Cell-Penetrating CDKL5 Protein Enhances the Efficacy of Gene Therapy for CDKL5 Deficiency Disorder
2022-01-01 Medici, Giorgio; Tassinari, Marianna; Galvani, Giuseppe; Bastianini, Stefano; Gennaccaro, Laura; Loi, Manuela; Mottolese, Nicola; Alvente, Sara; Berteotti, Chiara; Sagona, Giulia; Lupori, Leonardo; Candini, Giulia; Baggett, Helen Rappe; Zoccoli, Giovanna; Giustetto, Maurizio; Muotri, Alysson; Pizzorusso, Tommaso; Nakai, Hiroyuki; Trazzi, Stefania; Ciani, Elisabetta
Functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are rescued by a TrkB agonist
2019-01-01 Ren E.; Roncace V.; Trazzi S.; Fuchs C.; Medici G.; Gennaccaro L.; Loi M.; Galvani G.; Ye K.; Rimondini R.; Aicardi G.; Ciani E.
Functional cooperation between TrkA and p75NTR accelerates neuronal differentiation by increased transcription of GAP-43 and p21(CIP/WAF) genes via ERK1/2 and AP-1 activities
2007-01-01 Daniel Diolaiti; Roberto Bernardoni; Stefania Trazzi; Antonella Papa; Antonio Porro; Françoise Bono; Jean-Marc Herbert; Giovanni Perini; Giuliano Della Valle
Functional impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are ameliorated by a GABAB receptor antagonist
2020-01-01 Anna Cecilia Berardi, Claudia Fuchs, Laura Gennaccaro, Vincenzo Roncacè, Yassine Aitbali, Elisa Ren, Stefania Trazzi, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani
A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder
2021-01-01 Laura Gennaccaro, Claudia Fuchs, Manuela Loi, Vincenzo Roncacè, Stefania Trazzi, Yassine Ait-Bali, Giuseppe Galvani, Anna Cecilia Berardi, Giorgio Medici, Marianna Tassinari, Elisa Ren, Roberto Rimondini, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani
HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder
2016-01-01 Trazzi, Stefania; Fuchs, Claudia; Viggiano, Rocchina; De Franceschi, Marianna; Valli, Emanuele; Jedynak, Paulina; Hansen, Finn K; Perini, Giovanni; Rimondini, Roberto; Kurz, Thomas; Bartesaghi, Renata; Ciani, Elisabetta
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Age-related cognitive and motor decline in a mouse model of CDKL5 deficiency disorder is associated with increased neuronal senescence and death | Gennaccaro L.; Fuchs C.; Loi M.; Pizzo R.; Alvente S.; Berteotti C.; Lupori L.; Sagona G.; Galvan...i G.; Gurgone A.; Raspanti A.; Medici G.; Tassinari M.; Trazzi S.; Ren E.; Rimondini R.; Pizzorusso T.; Zoccoli G.; Giustetto M.; Ciani E. | 2021-01-01 | AGING AND DISEASE | - | 1.01 Articolo in rivista | Gennaccaro et al 2021Age.pdf |
| Age-related impairment of olfactory bulb neurogenesis in the Ts65Dn mouse model of Down syndrome | Bianchi P; Bettini S; Guidi S; Ciani E; Trazzi S; Stagni F; Ragazzi E; Franceschini V; Bartesaghi R. | 2014-01-01 | EXPERIMENTAL NEUROLOGY | - | 1.01 Articolo in rivista | - |
| APP-dependent alteration of GSK3β activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome. | Trazzi S;Fuchs C;De Franceschi M;Mitrugno VM;Bartesaghi R;Ciani E | 2014-01-01 | NEUROBIOLOGY OF DISEASE | - | 1.01 Articolo in rivista | - |
| APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome. | Trazzi S.; Mitrugno V.M.; Valli E.; Fuchs C.; Rizzi S.; Guidi S.; Perini G.; Bartesaghi R.; Ciani E. | 2011-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
| The C-Terminal Domain of CENP-C Displays Multiple and Critical Functions for Mammalian Centromere Formation. | Trazzi S.; Perini G.; Bernardoni R.; Zoli M.; Reese J. C.; Musacchio A.; Della Valle G. | 2009-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | journal.pone.0005832.pdf |
| CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/GSK-3{beta}/{beta}-catenin signaling | TRAZZI S.; STEGER M.; MITRUGNO V.M.; BARTESAGHI R.;CIANI E. | 2010-01-01 | THE JOURNAL OF BIOLOGICAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling (vol 29, pg 658, 2019) | Fuchs C.; Medici G.; Trazzi S.; Gennaccaro L.; Galvani G.; Berteotti C.; Ren E.; Loi M.; Ciani E. | 2019-01-01 | BRAIN PATHOLOGY | - | 1.01 Articolo in rivista | - |
| CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder | Trazzi, Stefania; De Franceschi, Marianna; Fuchs, Claudia; Bastianini, Stefano; Viggiano, Rocchin...a; Lupori, Leonardo; Mazziotti, Raffaele; Medici, Giorgio; Martire, Viviana Lo; Ren, Elisa; Rimondini, Roberto; Zoccoli, Giovanna; Bartesaghi, Renata; Pizzorusso, Tommaso; Ciani, Elisabetta* | 2018-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | trazzi2018 .pdf |
| CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells | VALLI E; TRAZZI S; FUCHS C; ERRIQUEZ D; BARTESAGHI R; PERINI G; CIANI E | 2012-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA. GENE REGULATORY MECHANISMS | - | 1.01 Articolo in rivista | - |
| CENP-C binds the alpha-satellite DNA in vivo at specific centromere domains | Politi, V; Perini, G; Trazzi, S; Pliss, A; Raska, I; Earnshaw, Wc; Della Valle, G | 2004-01-01 | JOURNAL OF CELL SCIENCE | - | 1.01 Articolo in rivista | - |
| DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions | Gopalakrishnan S.; Sullivan B. A.; Trazzi S.; Della Valle G.; Robertson K. D. | 2009-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
| Early Pharmacotherapy Restores Neurogenesis and Cognitive Performance in the Ts65Dn Mouse Model for Down Syndrome | P. Bianchi; E. Ciani; S. Guidi; S. Trazzi; D. Felice; G. Grossi; M. Fernandez; A. Giuliani; L. Ca...lza'; R. Bartesaghi | 2010-01-01 | THE JOURNAL OF NEUROSCIENCE | - | 1.01 Articolo in rivista | - |
| Early Pharmacotherapy with Fluoxetine Rescues Dendritic Pathology in the Ts65Dn Mouse Model of Down Syndrome | Sandra Guidi;Fiorenza Stagni;Patrizia Bianchi;Elisabetta Ciani;Elena Ragazzi;Stefania Trazzi;Gabr...iele Grossi;Chiara Mangano;Laura Calzà;Renata Bartesaghi | 2013-01-01 | BRAIN PATHOLOGY | - | 1.01 Articolo in rivista | - |
| Early-occurring proliferation defects in peripheral tissues of the Ts65Dn mouse model of Down syndrome are associated with patched1 over expression | Fuchs C; Ciani E; Guidi S; Trazzi S; Bartesaghi R | 2012-01-01 | LABORATORY INVESTIGATION | - | 1.01 Articolo in rivista | - |
| Expression of a Secretable, Cell-Penetrating CDKL5 Protein Enhances the Efficacy of Gene Therapy for CDKL5 Deficiency Disorder | Medici, Giorgio; Tassinari, Marianna; Galvani, Giuseppe; Bastianini, Stefano; Gennaccaro, Laura; ...Loi, Manuela; Mottolese, Nicola; Alvente, Sara; Berteotti, Chiara; Sagona, Giulia; Lupori, Leonardo; Candini, Giulia; Baggett, Helen Rappe; Zoccoli, Giovanna; Giustetto, Maurizio; Muotri, Alysson; Pizzorusso, Tommaso; Nakai, Hiroyuki; Trazzi, Stefania; Ciani, Elisabetta | 2022-01-01 | NEUROTHERAPEUTICS | - | 1.01 Articolo in rivista | - |
| Functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are rescued by a TrkB agonist | Ren E.; Roncace V.; Trazzi S.; Fuchs C.; Medici G.; Gennaccaro L.; Loi M.; Galvani G.; Ye K.; Rim...ondini R.; Aicardi G.; Ciani E. | 2019-01-01 | FRONTIERS IN CELLULAR NEUROSCIENCE | - | 1.01 Articolo in rivista | fncel-13-00169.pdf |
| Functional cooperation between TrkA and p75NTR accelerates neuronal differentiation by increased transcription of GAP-43 and p21(CIP/WAF) genes via ERK1/2 and AP-1 activities | Daniel Diolaiti; Roberto Bernardoni; Stefania Trazzi; Antonella Papa; Antonio Porro; Françoise Bo...no; Jean-Marc Herbert; Giovanni Perini; Giuliano Della Valle | 2007-01-01 | EXPERIMENTAL CELL RESEARCH | - | 1.01 Articolo in rivista | - |
| Functional impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are ameliorated by a GABAB receptor antagonist |
Anna Cecilia Berardi, Claudia Fuchs, Laura Gennaccaro, Vincenzo Roncacè, Yassine Aitbali, Elisa ...Ren, Stefania Trazzi, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani |
2020-01-01 | - | - | 4.03 Poster | - |
| A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder | Laura Gennaccaro, Claudia Fuchs, Manuela Loi, Vincenzo Roncacè, Stefania Trazzi, Yassine Ait-Bali..., Giuseppe Galvani, Anna Cecilia Berardi, Giorgio Medici, Marianna Tassinari, Elisa Ren, Roberto Rimondini, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani | 2021-01-01 | NEUROBIOLOGY OF DISEASE | - | 1.01 Articolo in rivista | Gennaccaro et al 2021GABA.pdf; Supplementary data.docx |
| HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder | Trazzi, Stefania; Fuchs, Claudia; Viggiano, Rocchina; De Franceschi, Marianna; Valli, Emanuele; J...edynak, Paulina; Hansen, Finn K; Perini, Giovanni; Rimondini, Roberto; Kurz, Thomas; Bartesaghi, Renata; Ciani, Elisabetta | 2016-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |