CHIARINI, FRANCESCA
CHIARINI, FRANCESCA
DIPARTIMENTO DI SCIENZE BIOMEDICHE E NEUROMOTORIE
Personale esterno ed autonomi
Antigene MYCN Silencing by BGA002 Inhibits SCLC Progression Blocking mTOR Pathway and Overcomes Multidrug Resistance
2023 Bortolotti, Sonia; Angelucci, Silvia; Montemurro, Luca; Bartolucci, Damiano; Raieli, Salvatore; Lampis, Silvia; Amadesi, Camilla; Scardovi, Annalisa; Nieddu, Giammario; Cerisoli, Lucia; Paganelli, Francesca; Chiarini, Francesca; Teti, Gabriella; Falconi, Mirella; Pession, Andrea; Hrelia, Patrizia; Tonelli, Roberto
Assessment of the structural and functional characteristics of human mesenchymal stem cells associated with a prolonged exposure of morphine
2021 Carano F.; Teti G.; Ruggeri A.; Chiarini F.; Giorgetti A.; Mazzotti M.C.; Fais P.; Falconi M.
Cellular senescence in vascular wall mesenchymal stromal cells, a possible contribution to the development of aortic aneurysm
2021 Teti G.; Chiarini F.; Mazzotti E.; Ruggeri A.; Carano F.; Falconi M.
Inhibition of methyltransferase dot1l sensitizes to sorafenib treatment aml cells irrespective of mll-rearrangements: A novel therapeutic strategy for pediatric aml
2020 Lonetti A.; Indio V.; Laginestra M.A.; Tarantino G.; Chiarini F.; Astolfi A.; Bertuccio S.N.; Martelli A.M.; Locatelli F.; Pession A.; Masetti R.
Lamin A and prelamin A counteract invasiveness of osteosarcoma cells
2020 Camilla Evangelisti, Francesca Paganelli, Gaia Giuntini, Elisabetta Mattioli, Alessandra Cappellini, Giulia Ramazzotti, Irene Faenza, Maria Cristina Maltarello, Alberto M. Martelli, Katia Scotlandi, Francesca Chiarini, Giovanna Lattanzi
The role played by Wnt/beta-catenin signaling pathway in acute lymphoblastic leukemia.
2020 Francesca Chiarini, Francesca Paganelli, Alberto M Martelli, Camilla Evangelisti.
The unfolded protein response: a novel therapeutic target in acute leukemias.
2020 A.M. Martelli, F. Paganelli, F. Chiarini, C. Evangelisti, J. J.A. McCubrey.
Lamin A acts a tumor suppressor in Ewing sarcoma promoting neural differentiation and reducing cell migration and invasion
2019 Chiarini F, Balestra T, Fazio A, Paganelli F, Maltarello MC, Evangelisti C, Capanni C, Petrini S, Martelli AM, Lattanzi G, Scotlandi K
Targeting metabolic vulnerabilities and aberrant signal transduction pathways in paediatric T-cell Acute Lymphoblastic Leukaemia (T-ALL)
2019 Laura Anselmi, Benedetta Accordi, Valentina Serafin, Manuela Zavatti, Luca Braglia, Maddalena Paganin, Francesca Chiarini, Silvia Bresolin, Shaun Patterson, Maria Ruzzene, Alberto Maria Martelli, Giuseppe Basso, Xu Huang, Sandra Marmiroli
PI3K pan-inhibition impairs more efficiently proliferation and survival of T-cell acute lymphoblastic leukemia cell lines when compared to isoform-selective PI3K inhibitors.
2015 Annalisa Lonetti, Alessandra Cappellini, Antonino Maria Spartà, Francesca Chiarini, Francesca Buontempo, Camilla Evangelisti, Cecilia Evangelisti, Ester Orsini, James A. McCubrey, Alberto Maria Martelli
A COMBINATION OF BORTEZOMIB WITH CX-4945, A CASEIN KINASE 2 (CK2) INHIBITOR, HAS SYNERGISTIC CYTOTOXIC EFFECTS IN ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) CELL LINES
2014 Buontempo, Francesca; Orsini, E; Cappellini, Alessandra; Lonetti, Annalisa; Evangelisti, C; Chiarini, Francesca; Spartà, Am; Bressanin, D; Evangelisti, C; Martelli, Am
ASSESSMENT OF THE EFFECT OF SPHINGOSINE KINASE INHIBITORS ON APOPTOSIS, UNFOLDED PROTEIN RESPONSE AND AUTOPHAGY OF T-ACUTE LYMPHOBLASTIC LEUKEMIA CELLS: INDICATIONS FOR NOVEL THERAPEUTICS
2014 Evangelisti, C; Evangelisti, C; Teti, G; Falconi, M; Cappellini, A; Chiarini, F; Buontempo, F; Bressanin, D; Lonetti, A; Spartà, A; Bittman, R; Pyne, S; Pyne, N; Martelli, Am
A role of PI-PLCb1 in G1/S transition in human erythroleukemia k562 cells
2012 Alessandro Poli; Irene Faenza; Alessandro Matteucci; Francesca Chiarini; Lucio Cocco
AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications.
2012 Grimaldi C.; Chiarini F.; Tabellini G.; Ricci F.; Tazzari P.L.; Battistelli M.; Falcieri E.; Bortul R.; Melchionda F.; Iacobucci I.; Pagliaro P.; Martinelli G.; Pession A.; Barata J.T.; McCubrey J.A.; Martelli A.M.
Temsirolimus, an mTOR inhibitor, in combination with lower-dose clofarabine as salvage therapy for older patients with acute myeloid leukaemia: results of a phase II GIMEMA study (AML-1107).
2012 Amadori S.; Stasi R.; Martelli A.M.; Venditti A.; Meloni G.; Pane F.; Martinelli G.; Lunghi M.; Pagano L.; Cilloni D.; Rossetti E.; Di Raimondo F.; Fozza C.; Annino L.; Chiarini F.; Ricci F.; Ammatuna E.; La Sala E.; Fazi P.; Vignetti M.
Effect of Lenalidomide Treatment on Lipid Signalling Pathways in Low-Risk MDS Patients
2011 Matilde Y Follo; Cristina Clissa; Sara Mongiorgi; Francesca Chiarini; Michele Baccarani; Giovanni Martinelli; Lucia Manzoli; Alberto M Martelli; Carlo Finelli; Lucio Cocco
Preclinical testing of the Akt inhibitor triciribine in T-cell acute lymphoblastic leukemia
2011 Evangelisti C; Ricci F; Tazzari P; Chiarini F; Battistelli M; Falcieri E; Ognibene A; Pagliaro P; Cocco L; McCubrey JA; Martelli AM
Synergistic induction of PI-PLCbeta1 signaling by azacitidine and valproic acid in high-risk myelodysplastic syndromes
2011 Follo MY; Finelli C; Mongiorgi S; Clissa C; Chiarini F; Ramazzotti G; Paolini S; Martinelli G; Martelli AM; Cocco L
Targeted inhibition of mTORC1 and mTORC2 by active-site mTOR inhibitors has cytotoxic effects in T-cell acute lymphoblastic leukemia.
2011 Evangelisti C.; Ricci F.; Tazzari P.; Tabellini G.; Battistelli M.; Falcieri E.; Chiarini F.; Bortul R.; Melchionda F.; Pagliaro P.; Pession A.; McCubrey J.A.; Martelli A.M.
Temsirolimus, An Allosteric mTORC1 Inhibitor, Is Synergistic with Clofarabine in AML and AML Leukemia Initiating Cells
2011 CHIARINI F; GRIMALDI C; RICCI F; TAZZARI PL; IACOBUCCI I; MARTINELLI G; PAGLIARO P; MCCUBREY J; AMADORI S; MARTELLI AM
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Antigene MYCN Silencing by BGA002 Inhibits SCLC Progression Blocking mTOR Pathway and Overcomes Multidrug Resistance | Bortolotti, Sonia; Angelucci, Silvia; Montemurro, Luca; Bartolucci, Damiano; Raieli, Salvatore; L...ampis, Silvia; Amadesi, Camilla; Scardovi, Annalisa; Nieddu, Giammario; Cerisoli, Lucia; Paganelli, Francesca; Chiarini, Francesca; Teti, Gabriella; Falconi, Mirella; Pession, Andrea; Hrelia, Patrizia; Tonelli, Roberto | 2023-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-15-00990.pdf |
| Assessment of the structural and functional characteristics of human mesenchymal stem cells associated with a prolonged exposure of morphine | Carano F.; Teti G.; Ruggeri A.; Chiarini F.; Giorgetti A.; Mazzotti M.C.; Fais P.; Falconi M. | 2021-01-01 | SCIENTIFIC REPORTS | - | 1.01 Articolo in rivista | 41598_2021_Article_98682.pdf; 41598_2021_98682_MOESM1_ESM.pdf |
| Cellular senescence in vascular wall mesenchymal stromal cells, a possible contribution to the development of aortic aneurysm | Teti G.; Chiarini F.; Mazzotti E.; Ruggeri A.; Carano F.; Falconi M. | 2021-01-01 | MECHANISMS OF AGEING AND DEVELOPMENT | - | 1.01 Articolo in rivista | 1-s2.0-S0047637421000877-main.pdf; 1-s2.0-S0047637421000877-mmc1.docx |
| Inhibition of methyltransferase dot1l sensitizes to sorafenib treatment aml cells irrespective of mll-rearrangements: A novel therapeutic strategy for pediatric aml | Lonetti A.; Indio V.; Laginestra M.A.; Tarantino G.; Chiarini F.; Astolfi A.; Bertuccio S.N.; Mar...telli A.M.; Locatelli F.; Pession A.; Masetti R. | 2020-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-12-01972.pdf; cancers-12-01972-s001.zip |
| Lamin A and prelamin A counteract invasiveness of osteosarcoma cells | Camilla Evangelisti, Francesca Paganelli, Gaia Giuntini, Elisabetta Mattioli, Alessandra Cappelli...ni, Giulia Ramazzotti, Irene Faenza, Maria Cristina Maltarello, Alberto M. Martelli, Katia Scotlandi, Francesca Chiarini, Giovanna Lattanzi | 2020-01-01 | CELLS | - | 1.01 Articolo in rivista | cells-09-00774.pdf; cells-09-00774-s001.zip |
| The role played by Wnt/beta-catenin signaling pathway in acute lymphoblastic leukemia. | Francesca Chiarini, Francesca Paganelli, Alberto M Martelli, Camilla Evangelisti. | 2020-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-21-01098.pdf |
| The unfolded protein response: a novel therapeutic target in acute leukemias. | A.M. Martelli, F. Paganelli, F. Chiarini, C. Evangelisti, J. J.A. McCubrey. | 2020-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-12-00333-v2.pdf |
| Lamin A acts a tumor suppressor in Ewing sarcoma promoting neural differentiation and reducing cell migration and invasion | Chiarini F, Balestra T, Fazio A, Paganelli F, Maltarello MC, Evangelisti C, Capanni C, Petrini S,... Martelli AM, Lattanzi G, Scotlandi K | 2019-01-01 | - | - | 4.03 Poster | - |
| Targeting metabolic vulnerabilities and aberrant signal transduction pathways in paediatric T-cell Acute Lymphoblastic Leukaemia (T-ALL) |
Laura Anselmi, Benedetta Accordi, Valentina Serafin, Manuela Zavatti, Luca Braglia, Maddalena Pag...anin, Francesca Chiarini, Silvia Bresolin, Shaun Patterson, Maria Ruzzene, Alberto Maria Martelli, Giuseppe Basso, Xu Huang, Sandra Marmiroli |
2019-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| PI3K pan-inhibition impairs more efficiently proliferation and survival of T-cell acute lymphoblastic leukemia cell lines when compared to isoform-selective PI3K inhibitors. | Annalisa Lonetti, Alessandra Cappellini, Antonino Maria Spartà, Francesca Chiarini, Francesca Buo...ntempo, Camilla Evangelisti, Cecilia Evangelisti, Ester Orsini, James A. McCubrey, Alberto Maria Martelli | 2015-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | PI3K pan inhibition impairs more efficiently proliferation and survival of T cell acute lymphoblastic leukemia cell lines when compared to isoform selective PI3K inhibitors..pdf |
| A COMBINATION OF BORTEZOMIB WITH CX-4945, A CASEIN KINASE 2 (CK2) INHIBITOR, HAS SYNERGISTIC CYTOTOXIC EFFECTS IN ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) CELL LINES | Buontempo, Francesca; Orsini, E; Cappellini, Alessandra; Lonetti, Annalisa; Evangelisti, C; Chiar...ini, Francesca; Spartà, Am; Bressanin, D; Evangelisti, C; Martelli, Am | 2014-01-01 | HAEMATOLOGICA | - | 4.02 Riassunto (Abstract) | - |
| ASSESSMENT OF THE EFFECT OF SPHINGOSINE KINASE INHIBITORS ON APOPTOSIS, UNFOLDED PROTEIN RESPONSE AND AUTOPHAGY OF T-ACUTE LYMPHOBLASTIC LEUKEMIA CELLS: INDICATIONS FOR NOVEL THERAPEUTICS | Evangelisti, C; Evangelisti, C; Teti, G; Falconi, M; Cappellini, A; Chiarini, F; Buontempo, F; Br...essanin, D; Lonetti, A; Spartà, A; Bittman, R; Pyne, S; Pyne, N; Martelli, Am | 2014-01-01 | HAEMATOLOGICA | - | 4.02 Riassunto (Abstract) | - |
| A role of PI-PLCb1 in G1/S transition in human erythroleukemia k562 cells | Alessandro Poli; Irene Faenza; Alessandro Matteucci; Francesca Chiarini; Lucio Cocco | 2012-01-01 | - | - | 4.03 Poster | - |
| AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications. | Grimaldi C.; Chiarini F.; Tabellini G.; Ricci F.; Tazzari P.L.; Battistelli M.; Falcieri E.; Bort...ul R.; Melchionda F.; Iacobucci I.; Pagliaro P.; Martinelli G.; Pession A.; Barata J.T.; McCubrey J.A.; Martelli A.M. | 2012-01-01 | LEUKEMIA | - | 1.01 Articolo in rivista | - |
| Temsirolimus, an mTOR inhibitor, in combination with lower-dose clofarabine as salvage therapy for older patients with acute myeloid leukaemia: results of a phase II GIMEMA study (AML-1107). | Amadori S.; Stasi R.; Martelli A.M.; Venditti A.; Meloni G.; Pane F.; Martinelli G.; Lunghi M.; P...agano L.; Cilloni D.; Rossetti E.; Di Raimondo F.; Fozza C.; Annino L.; Chiarini F.; Ricci F.; Ammatuna E.; La Sala E.; Fazi P.; Vignetti M. | 2012-01-01 | BRITISH JOURNAL OF HAEMATOLOGY | - | 1.01 Articolo in rivista | - |
| Effect of Lenalidomide Treatment on Lipid Signalling Pathways in Low-Risk MDS Patients | Matilde Y Follo; Cristina Clissa; Sara Mongiorgi; Francesca Chiarini; Michele Baccarani; Giovanni... Martinelli; Lucia Manzoli; Alberto M Martelli; Carlo Finelli; Lucio Cocco | 2011-01-01 | BLOOD | - | 4.01 Contributo in Atti di convegno | - |
| Preclinical testing of the Akt inhibitor triciribine in T-cell acute lymphoblastic leukemia |
Evangelisti C; Ricci F; Tazzari P; Chiarini F; Battistelli M; Falcieri E; Ognibene A; Pagliaro P;... Cocco L; McCubrey JA; Martelli AM |
2011-01-01 | JOURNAL OF CELLULAR PHYSIOLOGY | - | 1.01 Articolo in rivista | - |
| Synergistic induction of PI-PLCbeta1 signaling by azacitidine and valproic acid in high-risk myelodysplastic syndromes | Follo MY; Finelli C; Mongiorgi S; Clissa C; Chiarini F; Ramazzotti G; Paolini S; Martinelli G; Ma...rtelli AM; Cocco L | 2011-01-01 | LEUKEMIA | - | 1.01 Articolo in rivista | - |
| Targeted inhibition of mTORC1 and mTORC2 by active-site mTOR inhibitors has cytotoxic effects in T-cell acute lymphoblastic leukemia. | Evangelisti C.; Ricci F.; Tazzari P.; Tabellini G.; Battistelli M.; Falcieri E.; Chiarini F.; Bor...tul R.; Melchionda F.; Pagliaro P.; Pession A.; McCubrey J.A.; Martelli A.M. | 2011-01-01 | LEUKEMIA | - | 1.01 Articolo in rivista | - |
| Temsirolimus, An Allosteric mTORC1 Inhibitor, Is Synergistic with Clofarabine in AML and AML Leukemia Initiating Cells | CHIARINI F; GRIMALDI C; RICCI F; TAZZARI PL; IACOBUCCI I; MARTINELLI G; PAGLIARO P; MCCUBREY J; A...MADORI S; MARTELLI AM | 2011-01-01 | BLOOD | - | 4.02 Riassunto (Abstract) | - |