CHIARINI, FRANCESCA
CHIARINI, FRANCESCA
DIPARTIMENTO DI SCIENZE BIOMEDICHE E NEUROMOTORIE
Personale esterno ed autonomi
A role of PI-PLCb1 in G1/S transition in human erythroleukemia k562 cells
2012-01-01 Alessandro Poli; Irene Faenza; Alessandro Matteucci; Francesca Chiarini; Lucio Cocco
Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235, against T-cell acute lymphoblastic leukemia.
2010-01-01 F. Chiarini; C. Grimaldi; F. Ricci; P. L. Tazzari; C.Evangelisti; A. Ognibene; M.Battistelli; E. Falcieri; F. Melchionda; A. Pession; P. Pagliaro; J.A. McCubrey; A.M. Martelli.
Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy
2008-01-01 McCubrey J.A.; Sokolosky M.L.; Lehmann B.D.; Taylor J.R.; Navolanic P.M.; Chappell W.H.; Abrams S.L.; Stadelman K.M.; Wong E.W.; Misaghian N.; Horn S.; Bäsecke J.; Libra M.; Stivala F.; Ligresti G.; Tafuri A.; Milella M.; Zarzycki M.; Dzugaj A.; Chiarini F.; Evangelisti C.; Martelli A.M.; Terrian D.M.; Franklin R.A.; Steelman L.S.
AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications.
2012-01-01 Grimaldi C.; Chiarini F.; Tabellini G.; Ricci F.; Tazzari P.L.; Battistelli M.; Falcieri E.; Bortul R.; Melchionda F.; Iacobucci I.; Pagliaro P.; Martinelli G.; Pession A.; Barata J.T.; McCubrey J.A.; Martelli A.M.
ASSESSMENT OF THE EFFECT OF SPHINGOSINE KINASE INHIBITORS ON APOPTOSIS, UNFOLDED PROTEIN RESPONSE AND AUTOPHAGY OF T-ACUTE LYMPHOBLASTIC LEUKEMIA CELLS: INDICATIONS FOR NOVEL THERAPEUTICS
2014-01-01 Evangelisti, C; Evangelisti, C; Teti, G; Falconi, M; Cappellini, A; Chiarini, F; Buontempo, F; Bressanin, D; Lonetti, A; Spartà, A; Bittman, R; Pyne, S; Pyne, N; Martelli, Am
Assessment of the structural and functional characteristics of human mesenchymal stem cells associated with a prolonged exposure of morphine
2021-01-01 Carano F.; Teti G.; Ruggeri A.; Chiarini F.; Giorgetti A.; Mazzotti M.C.; Fais P.; Falconi M.
Cellular senescence in vascular wall mesenchymal stromal cells, a possible contribution to the development of aortic aneurysm
2021-01-01 Teti G.; Chiarini F.; Mazzotti E.; Ruggeri A.; Carano F.; Falconi M.
A COMBINATION OF BORTEZOMIB WITH CX-4945, A CASEIN KINASE 2 (CK2) INHIBITOR, HAS SYNERGISTIC CYTOTOXIC EFFECTS IN ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) CELL LINES
2014-01-01 Buontempo, Francesca; Orsini, E; Cappellini, Alessandra; Lonetti, Annalisa; Evangelisti, C; Chiarini, Francesca; Spartà, Am; Bressanin, D; Evangelisti, C; Martelli, Am
Dual inhibition of class IA phoshatidylinositol 3-kinase and mTOR as a new therapeutic option for T-cell acute lymphoblastic leukemia.
2009-01-01 F. Chiarini; F. Falà; P. L. Tazzari; F. Ricci; A. Astolfi; A. Pession; P. Pagliaro; J.A. McCubrey; A.M. Martelli.
Effect of Erythropoietin Treatment on Lipid Signalling Pathways in Low-Risk MDS Patients.
2009-01-01 Matilde Y Follo; Sara Mongiorgi; Cristina Clissa; Francesca Chiarini; Stefania Paolini; Michele Baccarani; Giovanni Martinelli; Lucia Manzoli; Alberto M. Martelli; Carlo Finelli; Lucio Cocco
Effect of Lenalidomide Treatment on Lipid Signalling Pathways in Low-Risk MDS Patients
2011-01-01 Matilde Y Follo; Cristina Clissa; Sara Mongiorgi; Francesca Chiarini; Michele Baccarani; Giovanni Martinelli; Lucia Manzoli; Alberto M Martelli; Carlo Finelli; Lucio Cocco
The Emerging Role of the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin Signaling Network in Cancer Stem Cell Biology.
2010-01-01 A.M. Martelli; C. Evangelisti; F. Chiarini; C. Grimaldi; J.A. McCubrey.
Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms.
2010-01-01 A.M. Martelli; V. Papa; P.L. Tazzari; F. Ricci; C. Evangelisti; F. Chiarini; C. Grimaldi; A. Cappellini; G. Martinelli; E. Ottaviani; P. Pagliaro; S. Horn; J. Bäsecke; L.H. Lindner; H. Eibl; J.A. McCubrey.
Inhibition of methyltransferase dot1l sensitizes to sorafenib treatment aml cells irrespective of mll-rearrangements: A novel therapeutic strategy for pediatric aml
2020-01-01 Lonetti A.; Indio V.; Laginestra M.A.; Tarantino G.; Chiarini F.; Astolfi A.; Bertuccio S.N.; Martelli A.M.; Locatelli F.; Pession A.; Masetti R.
Involvement of nuclear PLC{beta}1 in lamin B1 phosphorylation and G2/M cell cycle progression.
2009-01-01 Fiume R; Ramazzotti G; Teti G; Chiarini F; Faenza I; Mazzotti G; Billi AM; Cocco L
Lamin A acts a tumor suppressor in Ewing sarcoma promoting neural differentiation and reducing cell migration and invasion
2019-01-01 Chiarini F, Balestra T, Fazio A, Paganelli F, Maltarello MC, Evangelisti C, Capanni C, Petrini S, Martelli AM, Lattanzi G, Scotlandi K
Lamin A and prelamin A counteract invasiveness of osteosarcoma cells
2020-01-01 Camilla Evangelisti, Francesca Paganelli, Gaia Giuntini, Elisabetta Mattioli, Alessandra Cappellini, Giulia Ramazzotti, Irene Faenza, Maria Cristina Maltarello, Alberto M. Martelli, Katia Scotlandi, Francesca Chiarini, Giovanna Lattanzi
PI3K pan-inhibition impairs more efficiently proliferation and survival of T-cell acute lymphoblastic leukemia cell lines when compared to isoform-selective PI3K inhibitors.
2015-01-01 Annalisa Lonetti, Alessandra Cappellini, Antonino Maria Spartà, Francesca Chiarini, Francesca Buontempo, Camilla Evangelisti, Cecilia Evangelisti, Ester Orsini, James A. McCubrey, Alberto Maria Martelli
Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-ami ne (A443654) in T-cell acute lymphoblastic leukemia.
2008-01-01 Falà F; Blalock WL; Tazzari PL; Cappellini A; Chiarini F; Martinelli G; Tafuri A; McCubrey JA; Cocco L; Martelli AM
Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells
2008-01-01 V. Papa; P.L. Tazzari; F. Chiarini; A. Cappellini; F. Ricci; A.M. Billi; C. Evangelisti; E. Ottaviani; G. Martinelli; N. Testoni; J.A. McCubrey; A.M. Martelli
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| A role of PI-PLCb1 in G1/S transition in human erythroleukemia k562 cells | Alessandro Poli; Irene Faenza; Alessandro Matteucci; Francesca Chiarini; Lucio Cocco | 2012-01-01 | - | - | 4.03 Poster | - |
| Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235, against T-cell acute lymphoblastic leukemia. | F. Chiarini; C. Grimaldi; F. Ricci; P. L. Tazzari; C.Evangelisti; A. Ognibene; M.Battistelli; E. Falcieri; F. Melchionda; A. Pession; P. Pagliaro; J.A. McCubrey; A.M. Martelli. | 2010-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy | McCubrey J.A.; Sokolosky M.L.; Lehmann B.D.; Taylor J.R.; Navolanic P.M.; Chappell W.H.; Abrams S.L.; Stadelman K.M.; Wong E.W.; Misaghian N.; Horn S.; Bäsecke J.; Libra M.; Stivala F.; Ligresti G.; Tafuri A.; Milella M.; Zarzycki M.; Dzugaj A.; Chiarini F.; Evangelisti C.; Martelli A.M.; Terrian D.M.; Franklin R.A.; Steelman L.S. | 2008-01-01 | - | Elsevier Ltd. | 2.01 Capitolo / saggio in libro | - |
| AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications. | Grimaldi C.; Chiarini F.; Tabellini G.; Ricci F.; Tazzari P.L.; Battistelli M.; Falcieri E.; Bortul R.; Melchionda F.; Iacobucci I.; Pagliaro P.; Martinelli G.; Pession A.; Barata J.T.; McCubrey J.A.; Martelli A.M. | 2012-01-01 | LEUKEMIA | - | 1.01 Articolo in rivista | - |
| ASSESSMENT OF THE EFFECT OF SPHINGOSINE KINASE INHIBITORS ON APOPTOSIS, UNFOLDED PROTEIN RESPONSE AND AUTOPHAGY OF T-ACUTE LYMPHOBLASTIC LEUKEMIA CELLS: INDICATIONS FOR NOVEL THERAPEUTICS | Evangelisti, C; Evangelisti, C; Teti, G; Falconi, M; Cappellini, A; Chiarini, F; Buontempo, F; Bressanin, D; Lonetti, A; Spartà, A; Bittman, R; Pyne, S; Pyne, N; Martelli, Am | 2014-01-01 | HAEMATOLOGICA | - | 4.02 Riassunto (Abstract) | - |
| Assessment of the structural and functional characteristics of human mesenchymal stem cells associated with a prolonged exposure of morphine | Carano F.; Teti G.; Ruggeri A.; Chiarini F.; Giorgetti A.; Mazzotti M.C.; Fais P.; Falconi M. | 2021-01-01 | SCIENTIFIC REPORTS | - | 1.01 Articolo in rivista | - |
| Cellular senescence in vascular wall mesenchymal stromal cells, a possible contribution to the development of aortic aneurysm | Teti G.; Chiarini F.; Mazzotti E.; Ruggeri A.; Carano F.; Falconi M. | 2021-01-01 | MECHANISMS OF AGEING AND DEVELOPMENT | - | 1.01 Articolo in rivista | - |
| A COMBINATION OF BORTEZOMIB WITH CX-4945, A CASEIN KINASE 2 (CK2) INHIBITOR, HAS SYNERGISTIC CYTOTOXIC EFFECTS IN ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) CELL LINES | Buontempo, Francesca; Orsini, E; Cappellini, Alessandra; Lonetti, Annalisa; Evangelisti, C; Chiarini, Francesca; Spartà, Am; Bressanin, D; Evangelisti, C; Martelli, Am | 2014-01-01 | HAEMATOLOGICA | - | 4.02 Riassunto (Abstract) | - |
| Dual inhibition of class IA phoshatidylinositol 3-kinase and mTOR as a new therapeutic option for T-cell acute lymphoblastic leukemia. | F. Chiarini; F. Falà; P. L. Tazzari; F. Ricci; A. Astolfi; A. Pession; P. Pagliaro; J.A. McCubrey; A.M. Martelli. | 2009-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| Effect of Erythropoietin Treatment on Lipid Signalling Pathways in Low-Risk MDS Patients. | Matilde Y Follo; Sara Mongiorgi; Cristina Clissa; Francesca Chiarini; Stefania Paolini; Michele Baccarani; Giovanni Martinelli; Lucia Manzoli; Alberto M. Martelli; Carlo Finelli; Lucio Cocco | 2009-01-01 | BLOOD | - | 4.01 Contributo in Atti di convegno | - |
| Effect of Lenalidomide Treatment on Lipid Signalling Pathways in Low-Risk MDS Patients | Matilde Y Follo; Cristina Clissa; Sara Mongiorgi; Francesca Chiarini; Michele Baccarani; Giovanni Martinelli; Lucia Manzoli; Alberto M Martelli; Carlo Finelli; Lucio Cocco | 2011-01-01 | BLOOD | - | 4.01 Contributo in Atti di convegno | - |
| The Emerging Role of the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin Signaling Network in Cancer Stem Cell Biology. | A.M. Martelli; C. Evangelisti; F. Chiarini; C. Grimaldi; J.A. McCubrey. | 2010-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-02-01576.pdf |
| Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms. | A.M. Martelli; V. Papa; P.L. Tazzari; F. Ricci; C. Evangelisti; F. Chiarini; C. Grimaldi; A. Cappellini; G. Martinelli; E. Ottaviani; P. Pagliaro; S. Horn; J. Bäsecke; L.H. Lindner; H. Eibl; J.A. McCubrey. | 2010-01-01 | LEUKEMIA | - | 1.01 Articolo in rivista | - |
| Inhibition of methyltransferase dot1l sensitizes to sorafenib treatment aml cells irrespective of mll-rearrangements: A novel therapeutic strategy for pediatric aml | Lonetti A.; Indio V.; Laginestra M.A.; Tarantino G.; Chiarini F.; Astolfi A.; Bertuccio S.N.; Martelli A.M.; Locatelli F.; Pession A.; Masetti R. | 2020-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-12-01972.pdf; cancers-12-01972-s001.zip |
| Involvement of nuclear PLC{beta}1 in lamin B1 phosphorylation and G2/M cell cycle progression. | Fiume R; Ramazzotti G; Teti G; Chiarini F; Faenza I; Mazzotti G; Billi AM; Cocco L | 2009-01-01 | THE FASEB JOURNAL | - | 1.01 Articolo in rivista | - |
| Lamin A acts a tumor suppressor in Ewing sarcoma promoting neural differentiation and reducing cell migration and invasion | Chiarini F, Balestra T, Fazio A, Paganelli F, Maltarello MC, Evangelisti C, Capanni C, Petrini S, Martelli AM, Lattanzi G, Scotlandi K | 2019-01-01 | - | - | 4.03 Poster | - |
| Lamin A and prelamin A counteract invasiveness of osteosarcoma cells | Camilla Evangelisti, Francesca Paganelli, Gaia Giuntini, Elisabetta Mattioli, Alessandra Cappellini, Giulia Ramazzotti, Irene Faenza, Maria Cristina Maltarello, Alberto M. Martelli, Katia Scotlandi, Francesca Chiarini, Giovanna Lattanzi | 2020-01-01 | CELLS | - | 1.01 Articolo in rivista | cells-09-00774.pdf; cells-09-00774-s001.zip |
| PI3K pan-inhibition impairs more efficiently proliferation and survival of T-cell acute lymphoblastic leukemia cell lines when compared to isoform-selective PI3K inhibitors. | Annalisa Lonetti, Alessandra Cappellini, Antonino Maria Spartà, Francesca Chiarini, Francesca Buontempo, Camilla Evangelisti, Cecilia Evangelisti, Ester Orsini, James A. McCubrey, Alberto Maria Martelli | 2015-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | PI3K pan inhibition impairs more efficiently proliferation and survival of T cell acute lymphoblastic leukemia cell lines when compared to isoform selective PI3K inhibitors..pdf |
| Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-ami ne (A443654) in T-cell acute lymphoblastic leukemia. | Falà F; Blalock WL; Tazzari PL; Cappellini A; Chiarini F; Martinelli G; Tafuri A; McCubrey JA; Cocco L; Martelli AM | 2008-01-01 | MOLECULAR PHARMACOLOGY | - | 1.01 Articolo in rivista | - |
| Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells | V. Papa; P.L. Tazzari; F. Chiarini; A. Cappellini; F. Ricci; A.M. Billi; C. Evangelisti; E. Ottaviani; G. Martinelli; N. Testoni; J.A. McCubrey; A.M. Martelli | 2008-01-01 | LEUKEMIA | - | 1.01 Articolo in rivista | - |